Scientific Publications Database
Article Title: Surface-enhanced Raman scattering for the detection of polycystic ovary syndromeAuthors: Momenpour, Ali; Lima, Patricia D. A.; Chen, Yi-An; Tzeng, Chii-Ruey; Tsang, Benjamin K.; Anis, Hanan
Journal: BIOMEDICAL OPTICS EXPRESS Volume 9 Issue 2
Date of Publication:2018
Abstract:
Polycystic ovary syndrome (PCOS) is a multi-factorial heterogeneous syndrome that affects many women of reproductive age. This work demonstrates how the surface-enhanced Raman scattering (SERS) technique can be used to differentiate between PCOS and non-PCOS patients. We determine that the use of SERS, in conjunction with partial least squares (PLS) and principal component analysis (PCA), allows us to detect PCOS in patient samples. Although the role of chemerin in the pathogenesis of PCOS patients is not clear, this work enables us to measure their chemerin levels using the PLS regression method. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.