Scientific Publications Database

Article Title: Diagnosis of Venous Thromboembolism: 20 Years of Progress
Authors: Wells, Philip S.; Ihaddadene, Ryma; Reilly, Aoife; Forgie, Melissa Anne
Journal: ANNALS OF INTERNAL MEDICINE Volume 168 Issue 2
Date of Publication:2018
Abstract:
Many guidelines suggest incorporating clinical assessment, imaging, and D-dimer testing into diagnostic algorithms in patients with suspected deep venous thrombosis (DVT) and pulmonary embolism (PE). This special article reviews the evidence supporting the use of algorithms and their individual components for diagnosis of upper- and lower-extremity DVT and PE in adults, including pregnant women. The authors identified evidence through several electronic database searches to April 2017, evaluated the robustness of selected evidence, assessed whether diagnostic approaches that do not use algorithms are acceptable, and identified knowledge gaps that require further research.