Cancer Therapeutics Program


Startup company Virica Biotech aims to enhance production of viral medicines
October 4, 2021 - Virica Biotech, a startup company founded by Dr. Jean-Simon Diallo, announced a major funding milestone and the grand opening of its new process innovation facility this month.
Nothing about me, without me: Engaging patients in clinical trials
August 13, 2021 - It seems obvious – blindingly so – that patients, traditionally the subjects of clinical trials, should be involved as partners from the beginning. The benefits for patients are clear – an increased sense of control and the ability to learn about ...
Treatment while waiting for surgery for breast cancer - can it improve surgical outcomes?
June 23, 2021 - Drs. Angel Arnaout and Arif Awan are leading a clinical trial to determine if an experimental treatment can slow down the growth and spread of early stage breast cancer while activating the patient’s immune system before surgery
Cancer team awarded $5M for cell-based immunotherapy research
March 3, 2021 - Researchers at The Ottawa Hospital and the University of Ottawa are partnering with colleagues across the country to expand Canada’s capacity to develop new cell-based immunotherapies for cancer with a $5.2 million grant from the Canada ...
World-first clinical trial aims to protect cancer patients from COVID-19
December 9, 2020 - Our researchers are leading the way in a world-first clinical trial to protect vulnerable cancer patients during the COVID-19 pandemic.
Research reveals potential approach to make ovarian tumours ‘hot’
September 23, 2020 - In recent years, researchers have begun to recognize that some tumours are naturally “hot”, meaning they contain lots of immune cells that are actively fighting the cancer cells. Other tumours are “cold”, meaning, meaning they have little to no ...
Rock star researcher uses big data to answer big questions
September 18, 2020 - Growing up, David Cook knew he was going to be a rock star. Little did he know it would be as a researcher answering big questions with big data.
Protecting cancer patients from COVID-19
July 8, 2020 - In the race to find new ways to prevent and treat COVID-19, Canadian researchers have launched an innovative clinical trial focussed on strengthening the immune system for one of the most vulnerable populations – cancer patients.
Harnessing cancer-fighting viruses to develop a COVID-19 vaccine
June 25, 2020 - Drs. Carolina Ilkow, John Bell and colleagues are harnessing their expertise in making oncolytic (cancer-fighting) viruses to develop a vaccine against COVID-19, in partnership with scientists and clinicians in Canada and around the world.
The Ottawa Hospital awarded $4.7 million for COVID-19 research from the Canadian Institutes of Health Research
June 25, 2020 - Researchers at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $4.7 million from the Canadian Institutes of Health Research (CIHR) for four research projects that could transform our understanding of COVID-19 and ...


May 21, 2020 -  COVID-19 research on cell therapy, drug screening and marginalized populations funded through Ontario’s Rapid Research Fund
April 29, 2020 -  Researchers and research staff honoured for outstanding work in cancer clinical trials, emergency medicine, cell sorting and tissue collection
April 28, 2020 -  Cancer-killing viruses provide inspiration for COVID-19 vaccine
March 4, 2020 -  Dr. Barbara Vanderhyden wins uOttawa Award for Excellence in Research
February 20, 2020 -  Could biotherapeutics be the next revolution in cancer treatment?
February 20, 2020 -  Margaret's Gift
January 31, 2020 -  Can Type 2 diabetes be reversed? Research study available to Ottawa patients.
January 23, 2020 -  Prostate cancer study means more flexible treatment options for patients


December 3, 2019 -  How often should an incurable cancer be scanned? New evidence-based method shows the way
November 27, 2019 -  Researchers find potential biomarker to detect ovarian cancer earlier
November 27, 2019 -  Ottawa hosts hugely successful Canadian Cancer Research Conference
October 9, 2019 -  “Wild idea” opens possible new frontier for preventing ovarian cancer
October 1, 2019 -  Viral therapy for cancer: Frequently asked questions from patients and families
September 10, 2019 -  New research chair to lead cutting-edge work in liver and pancreatic cancer
July 26, 2019 -  The Ottawa Hospital awarded 13 grants worth $11.2 million from Canadian Institutes of Health Research
May 29, 2019 -  Researchers get $745,000 boost from NSERC
May 16, 2019 -  Clinical trials offer strong foundation for better patient care
April 15, 2019 -  Dr. John Bell wins public and patient engagement award
April 12, 2019 -  Dr. Barbara Vanderhyden receives international award for mentoring the scientists of tomorrow
March 22, 2019 -  Clinicians at The Ottawa Hospital launch 14 innovative projects to improve health-care delivery, thanks to funding from TOHAMO and The Ottawa Hospital’s Research Institute
March 1, 2019 -  Patients and clinical trial experts key to upcoming made-in-Canada CAR-T clinical trial
February 14, 2019 -  Researchers to advance science and improve health with new CIHR funding
January 17, 2019 -  TMIST - MAC.22
January 11, 2019 -  Award-winning immunology research shows how cancer surgery paralyzes part of the immune system


November 21, 2018 -  Researchers get $788,000 boost from NSERC
September 10, 2018 -  Often-overlooked Natural Killer cells may be key to cancer immunotherapy
August 30, 2018 -  Radioactive seeds for breast cancer surgery: better for patients and the health-care system
August 16, 2018 -  Targeting cancer stem cells improves survival in certain kinds of colorectal cancer
August 16, 2018 -  Using stem cells to treat brain cancer: pilot study highlights potential new approach
August 1, 2018 -  People with rare blood cancer live longer, healthier lives with new targeted treatment regimen
July 11, 2018 -  Estrogen and ovarian cancer: study provides first molecular link
July 11, 2018 -  Researchers uncover possible new mechanism to enhance cancer-killing viruses
May 17, 2018 -  Sex, viruses and cancer: Erectile dysfunction drugs and flu vaccine may work together to help immune system fight cancer after surgery
May 16, 2018 -  Colonoscopies save lives, but study finds room for improvement
May 3, 2018 -  Economics professor cancer-free after immunotherapy trial for skin cancer
April 19, 2018 -  Patients a “source of strength” for The Ottawa Hospital’s new head of cancer research
April 11, 2018 -  Exosomes open up exciting new avenue of leukemia research
March 29, 2018 -  Dr. Glen Goss recognized for lifetime achievement in lung cancer
March 19, 2018 -  Exploiting the Achilles’ heel of a severe form of childhood leukemia
February 7, 2018 -  MS drug makes cancer-fighting viruses more effective in lab models
January 30, 2018 -  The Ottawa Hospital awarded $12.7M for research, double the national CIHR success rate
January 19, 2018 -  Electromagnetic field therapy improves survival in brain cancer patients
January 3, 2018 -  Could viruses take cancer immunotherapy to the next level? Study shows viruses and checkpoint inhibitors work together to cure resistant breast cancer in mice


December 20, 2017 -  “Bait and switch” approach stimulates immune attack on cancer
November 6, 2017 -  Bolstering fat cells offers new hope for treating blood cancer
October 30, 2017 -  Dr. John Bell receives top award from Canadian Cancer Research Alliance
October 12, 2017 -  CFI provides $18-million boost to research on neuromuscular diseases, cancer-fighting viruses, the power of light and radioactive atoms
October 11, 2017 -  Ontario start-up makes major deal to develop cancer-fighting viruses
September 27, 2017 -  Cancer-fighting viruses: Canadian team to accelerate research with $7.4 million from Terry Fox Research Institute
September 6, 2017 -  Ottawa scientist wins Canada's top stem cell prize for multiple sclerosis trial
September 5, 2017 -  Innovative study brings next-generation genomic sequencing to more Ontario cancer patients
August 21, 2017 -  New Imaging Test Could Detect Heart Damage in Breast Cancer Patients Receiving Chemotherapy
July 18, 2017 -  Viral therapy effective against rare bone and muscle cancers in lab models
June 14, 2017 -  Trial opens door for new kind of drug for advanced breast cancer
June 14, 2017 -  Big data breakthrough: award-winning research helps scientists understand cancer gene expression
June 14, 2017 -  Dr. Michael McBurney recognized for leadership in cancer research
May 25, 2017 -  Ottawa cancer researchers to play lead role in new immunotherapy initiative, worth $4 million
May 19, 2017 -  The Ottawa Hospital awarded 18 research grants from the Canadian Institutes of Health Research, worth $10.7 million
May 18, 2017 -  Research on viral therapy for cancer research gets $6.5M boost
May 11, 2017 -  Awards honour those who make cancer clinical trials a reality
May 11, 2017 -  Study opens the door for targeted therapies for rare women’s cancer
May 4, 2017 -  Researcher’s activity gives teens new insights into cancer research
April 26, 2017 -  First cancer patient treated with a new experimental viral immunotherapy combination in a clinical trial
April 21, 2017 -  New calculator could reduce nausea and vomiting associated with cancer treatment
March 24, 2017 -  Cobra venom helps hybrid virus evade immune response and repeatedly attack tumours
March 2, 2017 -  Triple-threat viral vaccine cures abdominal cancer in animal models
March 1, 2017 -  Spit test helps diagnose some tongue and tonsil cancers
February 23, 2017 -  Could old drugs target lung cancer in a new way?
February 15, 2017 -  Ottawa researchers to play lead role in new cancer immunotherapy studies
February 8, 2017 -  Is 3D Mammography more effective in detecting breast cancer?
January 4, 2017 -  Information for patients: Chemo and blood stem cell transplantation for rare autoimmune diseases


December 14, 2016 -  Dr. David Stewart honoured for pioneering personalized medicine for cancer
November 2, 2016 -  Lung cancer breakthrough: 70% of patients with specific mutation respond to new therapy
November 2, 2016 -  Researchers find possible new molecular target for lung cancer treatment
November 2, 2016 -  Ontario start-up company secures US$41.4 million to advance cancer immunotherapy
October 11, 2016 -  $2-million project aims to bring personalized medicine to lung cancer care
September 7, 2016 -  Immediate hormone therapy for prostate cancer is better than delayed: study
August 24, 2016 -  Virus-chemo combination therapy shows promise in breast cancer models
July 6, 2016 -  Decision aid helps people with rectal cancer make tough choices
June 29, 2016 -  Surgery can prevent the immune system from attacking cancers
June 22, 2016 -  Trial compares targeted lung cancer treatments head-to-head
June 15, 2016 -  Experimental treatment gave new life to P.E.I. mother
June 14, 2016 -  Researchers find a way to supercharge cancer-fighting viruses
June 9, 2016 -  MS breakthrough: Replacing diseased immune system halts progression and allows repair
June 1, 2016 -  Lizzie’s lungs: New mother with lung cancer spreads hopeful story
May 18, 2016 -  Can a drug help prevent blood loss during bladder cancer surgery?
May 18, 2016 -  Immunotherapy harnesses our own immune system to fight cancer
April 26, 2016 -  Bench to bedside and back: basic and clinical scientists team up on potential cancer treatment
April 25, 2016 -  Researchers find potential new treatment target for deadly brain cancer
April 19, 2016 -  Unnecessary imaging for early stage breast cancer costs Ontario at least $4.4M over five years
April 13, 2016 -  Unexpected results lead to new breast cancer research direction
April 13, 2016 -  Dangerous infections slashed in cancer patients after implementation of electronic prescribing tool
March 30, 2016 -  When cancer comes back: Drug for mantle-cell lymphoma gives patients more time
March 2, 2016 -  Ottawa researchers find Achilles’ heel of a severe form of childhood leukemia
February 4, 2016 -  Terry Fox award helps Ottawa researcher develop next-generation cancer immunovirotherapy
February 3, 2016 -  Ottawa researcher lands spot in Canadian Cancer Society’s Top 10 Research Impact Stories of 2015
January 6, 2016 -  Electromagnetic field therapy improve survival in brain cancer patients


December 10, 2015 -  Controversial prostate cancer screening can be improved by repeating abnormal tests
December 8, 2015 -  Taking the Trojan horse to the next level: using fruit fly cells to deliver viral therapies for cancer
November 21, 2015 -  Applauding our Leading Researchers and Their Accomplishments at The Ottawa Hospital Gala
November 12, 2015 -  Personalized anti-nausea therapy better for cancer patients, Ottawa researchers
October 27, 2015 -  Countering the "Angelina effect": New study aims to understand and reduce fear of cancer recurrence
September 30, 2015 -  Virus vs. Prostate Cancer: Canadian Researchers Pioneer Next-generation Therapy -- Prostate Cancer Canada and the Movember Foundation partner to make innovative work possible
September 16, 2015 -  Clinical trial improved quality of life for cancer patient
September 16, 2015 -  Could a vaccine prevent cancer from spreading after surgery?
September 2, 2015 -  Targeted therapy improves survival in lung cancer patients
September 2, 2015 -  Tender Loving Research working to cure ovarian cancer
August 26, 2015 -  Tender Loving Research improves heart health for cancer survivors
August 19, 2015 -  Tender Loving Research drives passion for personalized medicine
August 19, 2015 -  Research reveals how cancer-fighting viruses infect tumour blood vessels
July 31, 2015 -  Former nurse receives experimental viral therapy for cancer at The Ottawa Hospital
July 28, 2015 -  The Ottawa Hospital awarded $28M from Canadian Institutes of Health Research for 22 research projects
July 22, 2015 -  Jean Maroun Scholarship recognizes resident’s research to help manage chemotherapy side effects
July 15, 2015 -  Ovarian cancer researcher recognized for excellence in education
July 10, 2015 -  Cancer patients treated in world-first clinical trial of Canadian viral therapy
July 8, 2015 -  Media advisory--Cancer patients treated in world-first clinical trial of Canadian viral therapy
June 22, 2015 -  Study reveals widespread over-imaging in early stage breast cancer patients in Ontario
June 17, 2015 -  Government of Ontario provides $10M boost for regenerative and biological therapeutics research in Ottawa
June 3, 2015 -  Breast cancer study among “Top 50 Most-Cited”
June 2, 2015 -  Local teacher with brain cancer beats the odds thanks to ‘bionic man’ therapy
May 20, 2015 -  Survey of health care providers and patients highlights need for standardization of use of the Breast Cancer drug, docetaxel.
May 13, 2015 -  Cancer clinical trial team receives prestigious award for the 2nd year in a row
May 4, 2015 -  Partners herald new cancer immunotherapy company
April 22, 2015 -  Ottawa Cardiac Oncology Program highlighted in the Report Card on Cancer in Canada
April 22, 2015 -  Viruses and drugs combine to form potent anti-cancer therapy
April 20, 2015 -  Pancreatic cancer loses viral defences when talking with supporting cells
April 15, 2015 -  Dr. Rebecca Auer awarded $450,000 to develop novel immunotherapy for pancreatic cancer
April 1, 2015 -  7 scientists at The Ottawa Hospital awarded uOttawa Faculty of Medicine Clinical Research Chairs
March 25, 2015 -  What controls the master controller of muscle development?
March 11, 2015 -  Could an oncolytic virus “melt” tumours?
March 11, 2015 -  Cancer-killing viruses featured by VICE on HBO, an international documentary show


December 15, 2014 -  The Ottawa Hospital to host $60M national research network for innovative cancer treatments
October 8, 2014 -  Using 3D imagery to improve breast cancer surgery
September 10, 2014 -  Is more exercise better for breast cancer patients undergoing chemotherapy?
April 15, 2014 -  Dr. Barbara Vanderhyden honoured by Governor General for volunteerism
March 26, 2014 -  Clinical trial shows benefit of new approach for metastatic breast cancer
January 23, 2014 -  Blasting blood clots to sic our natural killers on cancer
January 15, 2014 -  Genetic test could help tailor colorectal cancer therapy


December 18, 2013 -  Special recognition for research on viral and immune-based therapies for cancer
December 4, 2013 -  Regular exercise helps with side effects of chemotherapy
December 4, 2013 -  Experimental lung cancer drug shows promise
November 28, 2013 -  Ottawa researchers to play major role in $8.7M research project aimed at curing HIV
November 20, 2013 -  Prestigious U.S. grant to advance viral therapy for brain cancer
November 20, 2013 -  Research could solve prostate cancer controversy
November 9, 2013 -  The Ottawa Hospital fêtes three star researchers at annual Gala
September 4, 2013 -  Ottawa researchers contribute to Terry Fox Research Institute (TFRI)-led study that will improve lung cancer diagnosis
August 30, 2013 -  Dr. Ian Lorimer investigates approaches for converting brain cancer stem cells into a more treatable form
August 13, 2013 -  Virus-derived particles target blood cancer
August 8, 2013 -  New research led by Dr. Rebecca Auer suggests flu vaccine could help prevent the spread of cancer after surgery
June 14, 2013 -  Using math to kill cancer cells
March 19, 2013 -  Solving the mystery of how childhood brain cancer starts


October 11, 2012 -  The Terry Fox Foundation provides $13.4 million for world-class, novel research into fighting cancer with viruses and finding ways to treat acute leukemias
May 9, 2012 -  Dr. John Bell honoured for outstanding achievements with top Canadian Cancer Society research award
February 29, 2012 -  Major grant from Canadian Cancer Society supports Ottawa research on cancer surgery
January 24, 2012 -  Ottawa researchers discover new cancer-fighting virus


November 28, 2011 -  Study reveals novel approach to stop cancer cells from dividing
November 28, 2011 -  New research shows that second biopsy should be considered for some breast cancer patients
November 23, 2011 -  New research sheds light on molecular pathways involved in resistance to chemotherapy in ovarian cancer cells
November 5, 2011 -  The Ottawa Hospital Gala recognizes superstar researchers
October 26, 2011 -  New research sheds light on possible anti-cancer activity of FAK inhibitors
October 12, 2011 -  Early phase clinical trials shows promising results in advanced lung cancer
August 31, 2011 -  Results of world-first viral therapy trial in Ottawa cancer patients published in Nature
August 19, 2011 -  New research advances the development of personalized therapies for ovarian and breast cancer
June 29, 2011 -  The Ottawa Hospital’s new Centre for Innovative Cancer Research to reduce time between discovery and patient impact
May 26, 2011 -  The University of Ottawa and The Ottawa Hospital to use promising “blue light” in major clinical cancer study


November 15, 2010 -  New lead in the search for biomarkers for lung cancer treatment
September 15, 2010 -  The Ottawa Hospital Explores High-Tech Treatment for Pancreatic Tumours
May 28, 2010 -  Ontario invests $6.5M in regenerative medicine and cancer research in Ottawa
May 20, 2010 -  Viral therapy shows promise in ground-breaking clinical trial at The Ottawa Hospital Cancer Centre


June 24, 2009 -  OHRI cancer researcher Dr. John Bell profiled in The Ottawa Hospital's Annual Report
June 11, 2009 -  Ontario invests $18.5M in cancer and stem cell research at the Ottawa Hospital Research Institute and the University of Ottawa
June 2, 2009 -  OHRI / uOttawa scientist recognized with Y Women of Distinction Award
May 27, 2009 -  OHRI / uOttawa researcher recognized with CIHR Synapse Mentorship Award


November 17, 2008 -  Ontario researchers play key role in identifying new colorectal cancer genes
June 3, 2008 -  Dr. Doug Gray is investigating how lung cancer develops
May 22, 2008 -  Promising results with cancer-fighting virus


November 14, 2007 -  OHRI-led clinical trial demonstrates first evidence that new colorectal cancer drug saves lives
October 25, 2007 -  Top honours go to cancer and neuroscience researchers at the Ottawa Health Research Institute
October 20, 2007 -  OHRI researchers profiled in Ottawa Citizen breast cancer feature
May 24, 2007 -  $6.3M from Terry Fox Foundation to link researchers across Canada developing oncolytic virus therapies for cancer