Epigenetics

OCER Members

Kristen Baetz PhD Ottawa Institute of Systems Biology Characterization of the NuA4 acetyltransferase complex in Saccharomyces cerevisiae using function genomics and proteomics kbaetz@uottawa.ca Profile
Phil Berardi MD Ottawa Hospital Research Institute Chromatin remodeling during the normal cell cycle transition and how this changes through the multiple steps of oncogenic transformation in AML and MDS pberardi@toh.ca  
Alexandre Blais PhD Ottawa Institute of Systems Biology Formation and regeneration of skeletal muscle, and uses functional genomics approaches to reveal how transcription factors and the chromatin enzymes they interact with control these processes alexandre.blais@uottawa.ca Profile
Kym Boycott MD Children's Hospital of Eastern Ontario Research Institute Epigenetic modifications as disease biomarkers (Care for RARE) KBoycott@cheo.on.ca; KKernohan@cheo.on.ca (Kristin) Profile
Marjorie Brand PhD Ottawa Hospital Research Institute Characterizing the contribution of epigenetics enzymes to the development and maintenance of hematopoietic cancers mbrand@ohri.ca Profile
Patrick Burgon PhD University of Ottawa Heart Institute Epigenetics of perinatal heart development and cardiac adaptation pburgon@ottawaheart.ca Profile
Jocelyn Cote PhD University of Ottawa, Department of Cellular and Molecular Medicine The role(s) of Protein Arginine MethylTransferases and their Effectors/Readers in cancer and neuromuscular diseases jcote@uottawa.ca Profile
Jean-Francois Couture PhD Ottawa Institute of Systems Biology Structural characterization of epigenetic enymes and their interaction with chromatin Jean-Francois.Couture@uottawa.ca Profile
Jeff Dilworth PhD Ottawa Hospital Research Institute Epigenetics determinants of cell fate transitions during skeletal muscle regeneration jdilworth@ohri.ca Profile
Michael Downey PhD University of Ottawa, Department of Cellular and Molecular Medicine Non-canonical targets of post-translational modifications implicated in epigenetic control mdowne2@uottawa.ca Profile
Derrick Gibbings PhD University of Ottawa, Department of Cellular and Molecular Medicine Effects of changes in cell signaling, stress and biology on epigenetic control of gene expression focusing on models of cancer and neurodegenerative disease gibbings@uottawa.ca Profile
Ilya Ioshikhes PhD Ottawa Institute of Systems Biology Computational methods in epigenetics and gene regulation iioschik@uottawa.ca Profile
Bernard Jasmin PhD University of Ottawa, Department of Cellular and Molecular Medicine Epigenetic control of mRNA splicing jasmin@uottawa.ca Profile
Rashmi Kotahry PhD Ottawa Hospital Research Institute The use of small inhibitors targeting histone modifying enzymes to treat spinal muscular atrophy rkothary@ohri.ca Profile
David Lohnes PhD University of Ottawa, Department of Cellular and Molecular Medicine Epigenetic regulation of event in embyrogenesis that define early tissue lineages dlohnes@uottawa.ca Profile
Mike Organ PhD University of Ottawa, Centre for Catalysis Research and Innovation Medicinal chemistry approaches to develop novel molecules to inhibit epigenetic enzymes Organ@uottawa.ca Profile
Lynn Megeney PhD Ottawa Hospital Research Institute Role of DNA cleavage enzymes in regulating chromatin topology in muscle differentiation lmegeney@ohri.ca Profile
Keir Menzies PhD University of Ottawa, Interdisciplinary School of Health Sciences Metabolic control of epigentic enzymes in aging kmenzies@uottawa.ca Profile
Robin Parks PhD Ottawa Hospital Research Institute Epigenetic regulation of adenovirus replication rparks@ohri.ca Profile
Ted Perkins PhD Ottawa Hospital Research Institute Bioinformatics and machine learning-based analysis of high-throughput sequencing methodologies for studying epigenetic modifications and their transcriptional consequences tperkins@ohri.ca Profile
Dave Picketts PhD Ottawa Hospital Research Institute Understanding the role of ATP-dependent chromatin remodeling proteins in brain development and intellectual disability disorders. dpicketts@ohri.ca Profile
Katey Rayner PhD University of Ottawa Heart Institute Post-transcriptional mechanisms that control macrophage inflammatory responses in atherosclerosis, with a particular focus on microRNA- and lncRNA-based pathways KRayner@ottawaheart.ca Profile
Adam Rudner PhD Ottawa Institute of Systems Biology Mechanisms of heterochromatin assembly and epigenetic control of cell identity arudner@uottawa.ca Profile
Michael Rudnicki PhD Ottawa Hospital Research Institute Epigenetic control of myogenic specification for example during muscle stem cell asymmetric division mrudnicki@ohri.ca Profile
Mitchell Sabloff MD Ottawa Hospital Research Institute Epigenetic therapies for clinical treatment of leukemia MSABLOFF@toh.ca  
Ruth Slack PhD University of Ottawa, Department of Cellular and Molecular Medicine Epigenetic regulation of cell fate in neural stem cells rslack@uottawa.ca Profile
Bill Stanford PhD Ottawa Hospital Research Institute Epigenomic analysis of stem cell differentiation, development, and aging wstanford@ohri.ca Profile
Alexandre Stewart PhD University of Ottawa Heart Institute Epigenetics risk factors for cardiovascular disease astewart@ottawaheart.ca Profile
Duncan Stewart MD Ottawa Hospital Research Institute Role of miRNA in regulation of gene expression as well as the link between deficiency in the deacetylase, SIRT1 and PH, which appears to be regulate HIF-DNA interactions djstewart@ohri.ca Profile
Erik Suuronen PhD University of Ottawa Heart Institute Epigenetics that regulate communication between cells and their extracellular matrix environment esuuronen@ottawaheart.ca Profile
Mark Walker MD Ottawa Hospital Research Institute Clinical epidemiology of maternal nutrition on newborn health mwalker@toh.ca Profile
Jing Wang PhD Ottawa Hospital Research Institute Signaling-induced epigenetic pathway in brain regeneration during the normal adult brain development JIWang@ohri.ca Profile
Jodi Warman MD Children's Hospital of Eastern Ontario Research Institute Epigenetic basis of rare neuromuscular disorders jwarman@toh.on.ca Profile