Gonzalo G Alvarez profile picture

Contact Information

Gonzalo G Alvarez, MD, MPH, FRCPC
(613)737-8899 ext. 79294


ORCID logo https://orcid.org/0000-0003-1562-5305

Gonzalo G Alvarez

Scientist, Clinical Epidemiology Program
Ottawa Hospital Research Institute
Associate Professor, Faculty of Medicine, School of Epimediology, Public Health and Preventive Medicine
University of Ottawa
Staff Respirologist, Division of Respirology & Infections Disease; Department of Medicine
The Ottawa Hospital

Research Interests

Dr. Alvarez’s career aim is to study pulmonary health in disadvantaged populations specifically among Canadian Inuit and in new Canadians. He has concentrated his efforts on pulmonary tuberculosis (TB) research in these populations. He is currently leading the Taima TB program of research.. Taima (means stop in Inuktitut) TB is a group of research projects aimed at helping Inuit in Canada stop the transmission of TB in their communities. He has recently completed several studies in Nunavut with funding from the Public Health Agency of Canada, the Canadian Institutes for Health Research, the Canadian High Arctic Research Station, and the Ontario Thoracic Society focused on the implementation of innovative screening, diagnostic and education tools in the remote communities of Nunavut. These innovations have made a lasting improvement to TB care in Nunavut. At the moment, he is leading a study funded by the Public Health Agency of Canada (PHAC) and Health Canada to improve TB treatment capabilities for vulnerable people in Iqaluit, Nunavut and in Ottawa, Ontario.

Brief Biography

Dr. Alvarez is an Associate Professor of Medicine at The University of Ottawa and a Scientist at the Ottawa Hospital Research Institute (OHRI). He was appointed to the Division of Respirology in 2006 and cross appointed to the Division of Infectious Diseases at The Ottawa Hospital after completing 2 years as a clinical scholar during which he obtained his Masters of Public Health at Harvard University. In 2015, he was awarded the Clinical Research Chair in Tuberculosis in Aboriginal Communities at the University of Ottawa, Department of Medicine.

He has published 40 peer-reviewed journal articles and three book chapters. He has obtained over 1.6 million dollars in peer reviewed grants as either principle investigator or co-principle investigator, including 4 CIHR grants. His work has been featured on CBC TV and CBC radio as well as local, provincial and national newspapers.

In addition to his work serving the Ottawa region as a respirologist at The Ottawa Hospital, Dr. Alvarez is the respirology and tuberculosis consultant for the Nunavut Department of Health. Since 2007 he has been providing pulmonary care for Nunavummiut through the Qikiqtani General Hospital and in his Ottawa Hospital respirology and tuberculosis clinics.

Selected Publications

Efficacy and completion rates of rifapentine and isoniazid (3HP) compared to other treatment regimens for latent tuberculosis infection: a systematic review with network meta-analyses. Pease C, Hutton B, Yazdi F, Wolfe D, Hamel C, Quach P, Skidmore B, Moher D, and Alvarez GG.  BMC Infectious Diseases.  2017 Apr; 17:265

Developing and Field Testing a Community Based Youth Initiative to Increase Tuberculosis Awareness in Remote Arctic Inuit Communities. Alvarez GG, Van Dyk DD, Colquhoun H, Moreau KA, Mulpuru S, Graham ID. PLoS One. 2016 Jul 14;11(7):e0159241

Xpert®MTB/RIF for the Diagnosis of Tuberculosis in a Remote Arctic Setting: Impact on Cost and Time to Treatment Initiation. Oxlade O, Sugarman J, Alvarez GG, Pai M, Schwartzman K. PLoS One. 2016 Mar 18;11(3):e0150119

The feasibility, accuracy and impact of Xpert® MTB/RIF testing in a remote Aboriginal community in Canada. G.G. Alvarez, D.D.Van Dyk, M. Desjardins, A.S.Yasseen III, S.D. Aaron, D.W. Cameron, N.Obed, M.Baikie, S.Pakhale, C.M.Denkinger, H.Sohn, M.Pai. CHEST March 2015.

The feasibility of the interferon gamma release assay and predictors of discordance with the tuberculin skin test for the diagnosis of latent tuberculosis infection in a remote Aboriginal community. Alvarez GG, Van Dyk DD, Davies N, Aaron SD, Cameron DW, Desjardins M, Mallick R, Obed N, Baikie M. PLoS One. 2014 Nov 11;9(11)

TAIMA (Stop) TB: The Impact of a Multifaceted TB Awareness and Door-to-Door Campaign in Residential Areas of High Risk for TB in Iqaluit, Nunavut. Alvarez GG, VanDyk DD, Aaron SD, Cameron DW, Davies N, Stephen N, Mallick R, Mornoli F, Moreau K, Obed N, Baikie M, Osborne G. PLoS One. 2014 Jul 17;9(7)

Tuberculosis prevention and care in First Nations, Inuit and Métis Peoples. Alvarez GG, Orr P, Wobeser W, Cook V, Long R. Canadian Tuberculosis Standards 7th Edition. Canadian Respiratory Journal, July-Aug 2013.

Diseases, conditions and populations of interest

Research and clinical approaches