Kristopher Dennis profile picture

Contact Information

Kristopher Dennis, MD, FRCPC
613-737-7700x70212
krdennis@toh.on.ca

Kristopher Dennis

Clinician Investigator, Cancer Therapeutics Program
Ottawa Hospital Research Institute

Research Interests


My research interests include optimizing the quality and efficiency of common palliative radiation therapy treatments and understanding and preventing symptoms associated with advanced cancers and their treatments.

Brief Biography


Dr. Kristopher Dennis MD FRCPC is an assistant professor in the Division of Radiation Oncology at the University of Ottawa, Canada, and a radiation oncologist in the Radiation Medicine Program of The Ottawa Hospital where he leads the Rapid Palliative Radiation Therapy Program. Dr. Dennis is Chair of the Symptom Control Advisory Group of the Canadian Association of Radiation Oncology, Chair of the Canadian Palliative Radiation Oncology Group, a member of the Canadian Cancer Trials Group Symptom Control Executive Committee and an editor for the journal Supportive Care in Cancer.

Selected Publications


Dexamethasone in the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases: a double-blind, randomised placebo-controlled, phase 3 trial.
Chow E, Meyer RM, Ding K, Nabid A, Chabot P, Wong P, Ahmed S, Kuk J, Dar AR, Mahmud A, Fairchild A, Wilson CF, Wu JS, Dennis K, Brundage M, DeAngelis C, Wong RK.
Lancet Oncol. 2015 Nov;16(15):1463-72. doi: 10.1016/S1470-2045(15)00199-0. Epub 2015 Oct 18.
PMID: 26489389

Rapid access palliative radiation therapy programs: an efficient model of care.
Dennis K, Linden K, Balboni T, Chow E.
Future Oncol. 2015;11(17):2417-26. doi: 10.2217/FON.15.153. Epub 2015 Aug 13.
PMID: 26271002

Nausea and vomiting induced by gastrointestinal radiation therapy: current status and future directions.
Dennis K, Poon M, Chow E.
Curr Opin Support Palliat Care. 2015 Jun;9(2):182-8. doi: 10.1097/SPC.0000000000000130. Review.
PMID: 25872120

Single fraction conventional external beam radiation therapy for bone metastases: a systematic review of randomised controlled trials.
Dennis K, Makhani L, Zeng L, Lam H, Chow E.
Radiother Oncol. 2013 Jan;106(1):5-14. doi: 10.1016/j.radonc.2012.12.009. Epub 2013 Jan 13. Review.
PMID: 23321492 Free Article

International patterns of practice in the management of radiation therapy-induced nausea and vomiting.
Dennis K, Zhang L, Lutz S, van Baardwijk A, van der Linden Y, Holt T, Arnalot PF, Lagrange JL, Maranzano E, Liu R, Wong KH, Wong LC, Vassiliou V, Corn BW, De Angelis C, Holden L, Wong CS, Chow E.
Int J Radiat Oncol Biol Phys. 2012 Sep 1;84(1):e49-60. doi: 10.1016/j.ijrobp.2012.02.031. Epub 2012 Jun 15.
PMID: 22704982

Update on the systematic review of palliative radiotherapy trials for bone metastases.
Chow E, Zeng L, Salvo N, Dennis K, Tsao M, Lutz S.
Clin Oncol (R Coll Radiol). 2012 Mar;24(2):112-24. doi: 10.1016/j.clon.2011.11.004. Epub 2011 Nov 29. Review.
PMID: 22130630



Diseases, conditions and populations of interest


Cancer; Colorectal cancer; Other; Pain; Pancreatic cancer



Research and clinical approaches


Behaviour; Biomarkers; Biomarkers; Clinical research; Clinical trials; Health professional behaviour change; Palliative care; Qualitative methods