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Contact Information

Brian Hutton, MSc, PhD
7378899 ext 73842

Tina Hutchinson, Research Administrative Coordinator: 613-737-8899, ext 73920. Email:

Brian Hutton

Scientist, Clinical Epidemiology Program
Ottawa Hospital Research Institute
Director, Knowledge Synthesis Unit
Ottawa Hospital Research Institute
Assistant Professor, School of Epidemiology, Public Health and Preventive Medicine
University of Ottawa

Research Interests

Systematic reviews and meta-analysis network meta-analysis; technology assessment; statistical methods; oncology.

Brief Biography

Dr. Hutton is a Scientist with the OHRI's Clinical Epidemiology Program as well as an Assistant Professor within the University of Ottawa's Faculty of Epidemiology and Community Medicine. His primary research interests currently lie in the realm of network meta-analysis. He is a leader in the OHRI's CIHR-funded knowledge synthesis group which conducts network meta-analysis research projects for the Drug Safety and Effectiveness Network, with current topics including treatments for latent tuberculosis and allogeneic stem cell transplantation. Dr. Hutton was a 2013 recipient of a 5-year New Investigator Award from CIHR for his plans to expand applications of network meta-analysis in the area of drug safety. He has also led the development of the extension of the PRISMA statement for reporting of network meta-analyses. Dr. Hutton also contributes time to the Ottawa Hospital Methods Center and Ottawa Regional Cancer Center in the roles of methodologist and biostatistician. In these roles, he currently undertakes work related to the management of nausea and vomiting in patients undergoing chemotherapy, as well as assessing the benefits of complementary and s, and alternative forms of evidence synthesis products (see Teaching page for more detail).

Selected Publications

Access to many of the listed publications can be sought from

The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Hutton B, Salanti G, Caldwell DM, Chaimani A, Schmid CH, Cameron C, Ioannidis JP, Straus S, Thorlund K, Jansen JP, Mulrow C, Catalá-López F, Gøtzsche PC, Dickersin K, Boutron I, Altman DG, Moher D. Ann Intern Med. 2015 Jun 2;162(11):777-84.

Comparison of physical interventions, behavioral interventions, natural health products, and pharmacologics to manage hot flashes in patients with breast or prostate cancer: protocol for a systematic review incorporating network meta-analyses. Hutton B, Yazdi F, Bordeleau L, Morgan S, Cameron C, Kanji S, Fergusson D, Tricco A, Straus S, Skidmore B, Hersi M, Pratt M, Mazzarello S, Brouwers M, Moher D, Clemons M. Syst Rev. 2015 Aug 27;4(1):114

Network meta-analysis for comparing treatment effects of multiple interventions: an introduction. Catalá-López F, Tobías A, Cameron C, Moher D, Hutton B. Rheumatol International. 2014 Apr 2

The quality of reporting methods and results in network meta-analyses: an overview of reviews and suggestions for improvement. Hutton B, Salanti G, Chaimani A, Caldwell DM, Schmid C, Thorlund K, Mills E, Catalá-López F, Turner L, Altman DG, Moher D. PLoS One. 2014 Mar 26;9(3):e92508. doi: 10.1371/journal.pone.0092508. eCollection 2014.

Risks of harms using antifibrinolytics in cardiac surgery: systematic review and network meta-analysis of randomised and observational studies. Hutton B, Joseph L, Fergusson D, Mazer CD, Shapiro S, Tinmouth A. BMJ. 2012 Sep 11;345:e5798. doi: 10.1136/bmj.e5798.

Should de-escalation of bone-targeting agents be standard of care for patients with bone metastases from breast cancer? A systematic review and meta-analysis. Ibrahim MF, Mazzarello S, Shorr R, Vandermeer L, Jacobs C, Hilton J, Hutton B, Clemons M. Ann Oncol. 2015 Jun 28.

Diseases, conditions and populations of interest

Breast cancer; Cancer

Research and clinical approaches

Biostatistics; Clinical research; Clinical trials; Epidemiology; Health research methods; Public health; Rapid reviews; Systematic reviews