Addison Lab

Christina Addison profile picture

Contact Information

Christina Addison, PhD
613-737-7700 x70329
caddison@ohri.ca

Ottawa Hospital Research Institute
Centre for Cancer Therapeutics
501 Smyth Road
Box 926
Ottawa, ON
K1H 8L6

ORCID logo https://orcid.org/0000-0002-3492-475X

Publications

Selected Publications

*Howe, G., Xiao, B., Zhao, H., Al-Zahrani, K., Hasim, M.S., Villeneuve, J., Goss, G.D., Sekhon, H., Sabourin, L., Dimitroulakos, J., Addison, C.L. Enhanced anti-tumor activity of erlotinib in combination with focal adhesion kinase inhibitors in non-small cell lung cancer. In revision at PLoS One.

Addison, C.L., Ding, K., Seymour, L., Zhao, H., Laurie, S., Shepherd, F.A., Goss, G.D., Bradbury, P.A. 2015. Analysis of serum protein levels of angiogenic factors and their soluble receptors as markers of response to cediranib in the NCIC CTG BR.24 clinical trial. Lung Cancer, Nov; 90(2):288-95.

Addison, C.L., Pond, G.R, Cochrane, B., Zhao, H., Chia, S, Levine, M.N., Clemons, M. 2015. Correlation of Baseline K., Biomarkers with Clinical Outcomes and Response to Fulvestrant with Vandetanib or Placebo in Patients with Bone Predominant Metastatic Breast Cancer. An OCOG ZAMBONEY Sub-study. Journal of Bone Oncology. 4(2):47-53.

Addison, C.L., Bouganim, N., Kuchuk, I., Hilton, J., Vandermeer, L., Dent, S., Amir, E., Hopkins, S., Segal, R., Song, X., Gertler, S., Mazzarello, S., Dranitsaris, G., Ooi, D., Clemons, M. 2014. A Phase II, multicentre trial evaluating the efficacy of de-escalated bisphosphonate therapy in metastatic breast cancer patients at low-risk of skeletal related events. Breast Cancer Research and Treatment, Apr;144(3):615-24. doi: 10.1007/s10549-014-2906-x. Epub 2014 Mar 18.

*Honeywell, D.R., Cabrita, M.A., Zhao, H., Dimitroulakos, J., Addison, C.L. 2013. miR-105 Inhibits Prostate Tumor Growth by Suppressing CDK6 Levels. PLoS One, 8(8):e70515.doi:10.1371/journal.pone.0070515.

Al-Baimani K, Bazzarelli A, Clemons M, Robertson SJ, Addison C, Arnaout A. 2015. Invasive Pleomorphic Lobular Carcinoma of the Breast: Pathologic, Clinical, and Therapeutic Considerations. Clin Breast Cancer. pii: S1526-8209(15)00144-5. doi: 10.1016/j.clbc.2015.06.010.

Jacobs C, Ibrahim MF, Clemons M, Hutton B, Simos D, Caudrelier JM, Graham ID, Smith S, Addison C, Arnaout A. 2015. Treatment choices for patients with invasive lobular breast cancer: a doctor survey. J Eval Clin Pract., 21(4):740-8. doi: 10.1111/jep.12379.

Arnaout A, Robertson S, Kuchuk I, Simos D, Pond GR, Addison CL, Namazi M, Clemons M. 2015. Evaluating the feasibility of performing window of opportunity trials in breast cancer. Int J Surg Oncol. 2015:785793.

Addison CL, Pond GR, Zhao H, Mazzarello S, Vandermeer L, Goldstein R, Amir E, Clemons M. 2014. Effects of de-escalated bisphosphonate therapy on bone turnover biomarkers in breast cancer patients with bone metastases. Springerplus. 2014 Oct 1;3:577. doi: 10.1186/2193-1801-3-577.

Addison, C.L., Bouganim, N., Kuchuk, I., Hilton, J., Vandermeer, L., Dent, S., Amir, E., Hopkins, S., Segal, R., Song, X., Gertler, S., Mazzarello, S., Dranitsaris, G., Ooi, D., Clemons, M. 2014. A Phase II, multicentre trial evaluating the efficacy of de-escalated bisphosphonate therapy in metastatic breast cancer patients at low-risk of skeletal related events. Breast Cancer Research and Treatment, Apr;144(3):615-24. doi: 10.1007/s10549-014-2906-x. Epub 2014 Mar 18.


All Other Publications

Cabrita, MA, Jones, L., Quizi, JL, Sabourin, LA, McKay, BM and Addison, CL. 2011. Focal Adhesion Kinase Inhibitors are Potent Anti-angiogenic Agents. Molecular Oncology 5(6): 517-526.

Addison, C.L. Ding, K., Zhao, H., LeMaitre, A., Goss, G. D., Seymour L., Tsao, M-S., Shepherd F., Bradbury P.A. 2010. Evaluation of Plasma TGF-α and Amphiregulin Levels as Biomarkers of Response to Erlotinib in the NCIC Clinical Trials Group Study BR.21. Journal of Clinical Oncology. Dec 20, 28(36):5247-5256; published online on November 15, 2010.

Listings from The Ottawa Hospital Library

This lists the 5 most recent publications in The Ottawa Hospital's Library database from this lab.This database only starts tracking a researcher's publications once they start working at the Ottawa Hospital Research Institute.

Allen, Victoria; Coulombe, Josee; Zhao, Huijun; Kreps, Lauren M.; Cook, David P.; Pryce, Benjamin; Clemons, Mark; Vanderhyden, Barbara C.; Gray, Douglas A.; Addison, Christina L., 2022, VIVA1: a more invasive subclone of MDA-MB-134VI invasive lobular carcinoma cells with increased metastatic potential in xenograft models, BRITISH JOURNAL OF CANCER, 127, 1, 56-68 ➤ view abstract

Gunn, Scott A.; Kreps, Lauren M.; Zhao, Huijun; Landon, Katelyn; Ilacqua, Jacob S.; Addison, Christina L., 2022, Focal adhesion kinase inhibitors prevent osteoblast mineralization in part due to suppression of Akt-mediated stabilization of osterix, JOURNAL OF BONE ONCOLOGY, 34 ➤ view abstract

Kreps, Lauren M.; Addison, Christina L., 2021, Targeting Intercellular Communication in the Bone Microenvironment to Prevent Disseminated Tumor Cell Escape from Dormancy and Bone Metastatic Tumor Growth, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22, 6 ➤ view abstract

Brun, Emilie Marie Sophie Patit-Tha; Calvert, Nicholas David; Suchy, Mojmir; Kirby, Alexia; Melkus, Gerd; Garipov, Ruslan; Addison, Christina L.; Shuhendler, Adam J., 2021, Mapping vitamin B-6 metabolism by hydrazoCEST magnetic resonance imaging, CHEMICAL COMMUNICATIONS, 57, 83, 10867-10870 ➤ view abstract

Beltran-Bless, A.; Murshed, M.; Zakikhani, M.; Kuchuk, I; Bouganim, N.; Robertson, S.; Kekre, N.; Vandermeer, L.; Li, J.; Addison, C. L.; Rauch, F.; Clemons, M.; Kremer, R., 2021, Histomorphometric and microarchitectural analysis of bone in metastatic breast cancer patients, BONE REPORTS, 15 ➤ view abstract

More publications may be available in The Ottawa Hospital Library database.

PubMed Listings

For more publications use this PubMed ID link.