Caryn Ito profile picture

Contact Information

Caryn Ito, PhD
613 737 8899 73354
cito@ohri.ca

ORCID logo https://orcid.org/0000-0003-1611-6596

Caryn Ito

Senior Investigator, Regenerative Medicine Program
Ottawa Hospital Research Institute

Research Interests

Brief Biography

Selected Publications

Selected Publications:
1.     Csaszar E, Kirouac DC, Yu M, Wang W, Qiao W, Cooke MP, Boitano AE, Ito C and Zandstra PW. (2012)  Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling.  Cell Stem Cell 10(2):218-29
2.     Kirouac DC, Ito C, Csaszar E, Roch A, Yu M, Sykes EA, Bader GD and Zandstra PW. (2010).  Dynamic interaction networks in a hierarchically organized tissue.  Mol Syst Biol 6:417
3.     Ito CY, Kirouac DC, Madlambayan GJ, Yu M, Rogers I and Zandstra PW. (2010) The AC133+CD38-, but not the rhodamine-low, phenotype tracks LTC-IC and SRC function in human cord blood ex vivo expansion cultures.  Blood 115(2):257-60
4.     Kirouac DC, Madlambayan GJ, Yu M, Sykes E, Ito C and Zandstra PW.  (2009) Cell0cell interaction nteworks regulate blood stem and projenitor cell fate. Mol Syst Biol 5:293
5.     Madlambayan GJ, Rogers I, Purpura KA, Ito C, Yu M, Kirouac D, Casper RF and Zandstra PW.  (2006) Clinically relevant expansion of hematopoietic stem cells with conserved function in a single-use, closed-system bioprocess. Biol Blood Marrow Transplant.  12(10):1020-30

Diseases, conditions and populations of interest


Blood cancer; Cancer



Research and clinical approaches


Basic research; Bioinformatics; Biomarkers; Drug development; Epigenetics; Molecular and cellular biology; Proteomics; Regenerative medicine; Stem cells; Systems biology; Translational research