David Allan profile picture

Contact Information

David Allan, MD FRCPC
75055
daallan@ohri.ca

Publications

Selected Publications

Top Publications

Cell-based Regenerative Therapy


1. Damien P*, Allan DS. Use of umbilical cord blood cells in regenerative therapy. Biol Blood Marrow Transplant, 2015; 21:1545-1554. [PMID 26079441]

2. Akyurekli C*, Le Y*, Richardson R, Fergusson D, Tay J, Allan DS. A systematic review of preclinical studies on the therapeutic potential of mesenchymal stromal cell-derived microvesicles. Stem Cell Rev & Reports, 2015; 11:150-160. [PMID 25091427]

3. Palii C, Vulesevic B, Fraineau S, Pranckeviciene E, Griffith AJ, Chu A, Faralli H, Li Y, McNeill B, Sun J, Perkins TJ, Dilworth FJ, Perez-Iratxeta C, Suuronen EJ+, Allan DS+, Brand M+. Trichostatin A enhances the vascular repair function of injected human endothelial progenitors by increasing the expression of TAL1-dependent genes. Cell Stem Cell, 2014; 14:644-657. [PMID 24792117]

Hematopoietic Stem Cells & Transplantation

4. Le Y*, Fraineau S*, Chandran P*, Brand M, Sabloff M, Richardson R, Allan DS. Adipogenic mesenchymal stromal cells from bone marrow and their hematopoietic supportive role: towards an understanding of a permissive marrow microenvironment in acute myeloid leukemia. Stem Cell Rev & Rep, 2015 (accepted).

5. Chandran P*, Le Y*, Li Y, Sabloff M, Mehic J, Rosu-Myles M, Allan DS. Mesenchymal stromal cells from patients with acute myeloid leukemia have altered capacity to expand differentiated hematopoietic progenitors. Leuk Res, 2015; 39:486-493. [PMID 25703353]



Selected Peer-reviewed Publications [past 4 years]

Trainees under my supervision are marked with (*); supervisor or PI listed last.

Cell-based Regenerative Therapy: Discovery & Translational Research

1. Damien P*, Allan DS. Use of umbilical cord blood cells in regenerative therapy. Biol Blood Marrow Transplant, 2015; 21:1545-1554. [PMID 26079441]

2. Burger D, Viñas JL, Akbari S, Dehak H, Knoll W, Gutsol A, Allan DS, Touyz R, Burns KD. Human cord blood-derived endothelial colony forming cells are protective in ischemic acute kidney injury in mice. Am J Path, 2015; 185:2309-2323. [PMID 26073035]

3. Fraineau S*, Palii CG, Allan DS, Brand M. Epigenetic Regulation of Endothelial Stem/Progenitor Cell-mediated Vascular Repair. FEBS J, 2015; 282:1605-1629. [PMID 25546332]

4. Akyurekli C*, Le Y*, Richardson R, Fergusson D, Tay J, Allan DS. A systematic review of preclinical studies on the therapeutic potential of mesenchymal stromal cell-derived microvesicles. Stem Cell Rev & Reports, 2015; 11:150-160. [PMID 25091427]

5. Palii C, Vulesevic B, Fraineau S, Pranckeviciene E, Griffith AJ, Chu A, Faralli H, Li Y, McNeill B, Sun J, Perkins TJ, Dilworth FJ, Perez-Iratxeta C, Suuronen EJ+, Allan DS+, Brand M+. Trichostatin A enhances the vascular repair function of injected human endothelial progenitors by increasing the expression of TAL1-dependent genes. Cell Stem Cell, 2014; 14:644-657. [PMID 24792117]

6. Javidnia H*, Hanna M*, Li Y, Scheer A, Filion L, Eapen L, Carrier M, Auer R, Corsten M, Allan DS. Vascular progenitor clusters from peripheral blood in cancer patients following oncologic surgery. Journal of Surgical Oncology 2014; 109:151-157. [PMID 24449173].

7. Iafolla MAJ*, Tay J, Allan DS. Transplantation of umbilical cord blood-derived cells for novel indications in regenerative or immunomodulatory therapy: a scoping review of clinical studies. Biol Blood Marrow Transplant, 2014; 20:20-25. [PMID 24067504]

8. Sun J*, Li Y, Graziani GM, Filion L, Allan DS. E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1α/CXCR4 . PLoS ONE, 2013; 8:e60890. [PMID 23565284]

9. Burger D, Gutsol A, Carter A, Allan DS, Touyz RM, Burns KD. Human umbilical cord blood CD133(+) cells exacerbate acute kidney injury in NOD/SCID mice. Neph Dialysis Transplant, 2012; 27: 3781-9.

10. Labonté L*, Li Y, Addison CL, Brand M, Javidnia H, Cortsen M, Burns KD, Allan DS. Integrin-mediated binding of angiogenic precursors to extracellular matrix proteins is altered in cancer patients. Clinical & Investigative Medicine, 2012; 35:E86-95.

Hematopoietic Stem Cell Donation, Transplantation & Biology

11. Le Y*, Fraineau S*, Chandran P*, Brand M, Sabloff M, Richardson R, Allan DS. Adipogenic mesenchymal stromal cells from bone marrow and their hematopoietic supportive role: towards an understanding of a permissive marrow microenvironment in acute myeloid leukemia. Stem Cell Rev & Rep, 2015 (accepted).

12. Allan DS, Scrivens N, Lawless T, Mostert K, Oppenheimer L, Walker M, Petraszko T, Elmoazzen H. Delayed clamping of the umbilical cord following delivery and implications for public cord blood banking. Transfusion, 2015 (epub ahead of print, Nov 20, 2015. doi: 10.1111/trf.13424.) [PMID: 26585667]

13. Armson A, Allan DS, Casper R. Umbilical cord blood: counselling, collection and banking.J Obs Gyn Can, 2015; 37:832-844.

14. Chandran P*, Le Y*, Li Y, Sabloff M, Mehic J, Rosu-Myles M, Allan DS. Mesenchymal stromal cells from patients with acute myeloid leukemia have altered capacity to expand differentiated hematopoietic progenitors. Leuk Res, 2015; 39:486-493. [PMID 25703353]

15. Pilon S*, Jedrysiak D, Sheppard D, Bredeson C, Tay J, Allan DS. Current trends in clinical studies of allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant, 2015; 21:364-370. [PMID 25445635]

16. Christou G*, Kekre N*, Petrich W, Tokessy M, Neurath D, Giulivi A, Saidenberg E, McDiarmid S, Atkins H, Bence-Bruckler I, Bredeson C, Huebsch L, Sabloff M, Tay J, Tinmouth A, Allan DS. Impact of Platelet Transfusion on Toxicity and Mortality Following Hematopoietic Progenitor Cell Transplantation. Transfusion, 2015; 55:253-8. [PMID 25125085]

17. Sheppard D, Bredeson C, Huebsch LB, Allan D, Tay J. A plerixafor-based strategy allows adequate hematopoietic stem cell collection in poor mobilizers: Results from the Canadian Special Access Program. Bone Marrow Transplant, 2014; 49:751-755. [PMID 24614838]

18. Akyurekli C*, Chan JYS*, Elmoazzen H, Tay J, Allan DS. Impact of ethnicity on human umbilical cord blood banking: a systematic review. Transfusion, 2014; 54:2122-2127. [PMID 24697816]

19. Allan DS, Petraszko T, Elmoazzen H, Smith S. A review of factors influencing the banking of collected umbilical cord blood. Stem Cells International, 2013; 2013:463031. [PMID 23533442]

20. Kekre N*, Phillippe J, Mallick R, Smith S, Allan DS. Modelling improvements in cell yield of banked umbilical cord blood and the impact on availability of donor units for transplantation into adults. Stem Cells International, 2013; 2013:124834. [PMID 23509469]

21. Sheppard D, Bredeson C, Allan DS, Tay J. Systematic review of randomized controlled trials of hematopoietic stem cell mobilization strategies for autologous transplantation for hematologic malignancies. Biol Blood Marrow Transplant, 2012; 18:1191-203.

22. Wu L*, Al-Hejazi A*, Filion L, Ben R, Halpenny M, Yang L, Giulivi A, Allan DS. Increased apoptosis in cryopreserved PBSCs and delayed neutrophil recovery after transplantation: a nested case-control study. Cytotherapy, 2012; 205-214.

23. Kekre N*, Chou A*, Tokessy M, Doucette S, Tinmouth A, Tay J, Allan DS. Storage time of transfused red blood cells and impact on clinical outcomes in hematopoietic stem cell transplantation. Transfusion, 2011; 51:2488-94.

PubMed Listings

For more publications use this PubMed ID link.