Duane Hickling profile picture

Contact Information

Duane Hickling, M.D.,M.SCI., FRCSC
613-761-4500

Ms. Terri van Gulik
613-737-8899 x 72807

Duane Hickling

Associate Scientist, Chronic Disease Program
Ottawa Hospital Research Institute
Greta and John Hansen Chair in Men's Health and Basic Science Research, Division of Urology, Department of Surgery
Ottawa Hospital Research Institute
Assistant Professor, Divison of Urology, Department of Surgery
University of Ottawa

Research Interests

Research Interests:

 1.  Host Defense Mechanisms in Urinary Tract Infection The overall goal of our research is to better understand UTI pathogenesis as it relates to the host.  Specifically, we are interested in studying constitutive and inducible expression of antimicrobial peptides/host defense proteins in the lower urinary tract.   At the present time, our program integrates in vitro, in vivo and clinical approaches to better understand the roles of LL-37 in UTI pathogenesis.   This important work will lay the foundation for future translational projects pertaining to the UTI and catheter biofilm prevention.  

 2. Recurrent Urinary Tract Infections This research program is focused primarily on uncovering those clinical factors that make some individuals prone to recurrent UTI.  By studying patient demographics and select biomarkers we hope to gain a better understanding of susceptibility to UTI in certain at risk populations and in those who are otherwise seemingly healthy.

Brief Biography

Dr. Duane Hickling has recently joined the Ottawa Hospital Research Institute as an Associate Scientist in the Chronic Disease Program. His research focuses on urinary tract infections and understanding how the body defends against these at the molecular level. Dr. Hickling is also a urologist at The Ottawa Hospital and Assistant Professor in the Division of Urology, Department of Surgery, Faculty of Medicine at the University of Ottawa. After obtaining his MD at Western University, he completed his residency training at The Ottawa Hospital/University of Ottawa and then went on to do a three-year combined clinical and research fellowship at New York University. There he trained in female pelvic medicine and reconstructive surgery, receiving a Master’s degree in Clinical Investigation – Translational Research. 

Selected Publications

1. Thermal Bladder Injury at Laparoscopic Hysterectomy. Clancy AA, Hickling D. J Minim Invasive Gynecol. 2017 Aug 10. pii: S1553-4650(17)30449-1. doi: 10.1016/j.jmig.2017.08.010. [Epub ahead of print] No abstract available.  

2. Patient-targeted websites on overactive bladder: What are our patients reading? Clancy AA, Hickling D, Didomizio L, Sanaee M, Shehata F, Zee R, Khalil H. Neurourol Urodyn. 2017 Aug 1. doi: 10.1002/nau.23359. [Epub ahead of print]  

3. The role of preoperative urodynamics in stress urinary incontinence surgery. Hickling DR, Steele SS. Can Urol Assoc J. 2017 Jun;11(6Suppl2):S113-S115. doi: 10.5489/cuaj.4581. Review.  

4. Canadian Urological Association position statement on the use of transvaginal mesh. Welk B, Carlson KV, Baverstock RJ, Steele SS, Bailly GG, Hickling DR. Can Urol Assoc J. 2017 Jun;11(6Suppl2):S105-S107. doi: 10.5489/cuaj.4579. Review.  

5. Appendix: Executive summary of CUA guideline on adult overactive bladder. Corcos J, Przydacz M, Campeau L, Gray G, Hickling D, Honeine C, Radomski SB, Stothers L, Wagg A. Can Urol Assoc J. 2017 May;11(5):E248-E249. Epub 2017 May 9. No abstract available. Erratum in: Can Urol Assoc J. 2017 Jul;11(7):E323.  

6. CUA guideline on adult overactive bladder. Corcos J, Przydacz M, Campeau L, Gray G, Hickling D, Honeine C, Radomski SB, Stothers L, Wagg A, Lond F. Can Urol Assoc J. 2017 May;11(5):E142-E173. doi: 10.5489/cuaj.4586. Epub 2017 May 9. No abstract available. Erratum in: Can Urol Assoc J. 2017 May;11(5):E250. Can Urol Assoc J. 2017 Jul;11(7):E323.  

7. Risk Factors for Urinary Tract Infection following Mid Urethral Sling Surgery. Vigil HR, Mallick R, Nitti VW, Lavallée LT, Breau RH, Hickling DR. J Urol. 2017 May;197(5):1268-1273. doi: 10.1016/j.juro.2016.12.093. Epub 2016 Dec 27.