Dylan Burger profile picture

Contact Information

Dylan Burger, PhD
613-562-5800 x 8241
dburger@uottawa.ca

2513-451 Smyth Rd.
Ottawa, ON
K1H 7N9



ORCID logo https://orcid.org/0000-0003-3951-2911

Publications

Selected Publications

1. Burger D+*, Turner M, Xiao F, Munkonda M, Akbari S, Burns KD* (2017) “High glucose increases the formation and pro-oxidative activity of endothelial microparticles”. Diabetologia (Epub ahead of print).

2. Akbari S, Abou-Arkoub R, Sun S, Hiremath S, Reunov A, McCormick B*, Ruzicka M*, Burger D*+ (2017) “Microparticle formation in peritoneal dialysis: a proof of concept study”. Can J Kid Health Dis 4: 1-8.

3. Lytvyn Y, Xiao F, Perkins BA, Kennedy CR, Reich HN, Scholey JW, Cherney DZ, Burger D+ (2017) “Assessment of Urinary Microparticles in Normotensive Patients with Type 1 Diabetes”. Diabetologia, 60(3) 581-584.

4. Olsen MH, Angell SY, Asma S, Boutouyrie P, Burger D, Chirinos JA, Damasceno A, Delles C, Giminez-Roqueplo A, Hering D, López-Jaramillo P, Martinez F, Perkovic V, Rietzschel ER, Schillaci G, Schutte AE, Scuteri A, Sharman JE, Wachtell K, Wang JG (2016) “A call to action and a life-course strategy to address the global burden of raised blood pressure on current and future generations: The Lancet Commission on Hypertension”. Lancet 26;388(10060):2665-2712.

5. Burger D, Thibodeau JF, Holterman CE, Burns KD, Touyz RM, Kennedy CRJ (2014) “Urinary podocyte microparticles identify pre-albuminuric diabetic glomerular injury”. J Am Soc Nephrol 25(7) 1401-1407

6. Burger D+, Schock S, Thompson CS, Montezano AC, Hakim AM, Touyz RM (2013) “Microparticles: Biomarkers and Beyond”. Clin Sci 124(7) 423-441

All Other Publications

1. Burger D+*, Turner M, Xiao F, Munkonda M, Akbari S, Burns KD* (2017) “High glucose increases the formation and pro-oxidative activity of endothelial microparticles”. Diabetologia (Epub ahead of print).

2. Akbari S, Abou-Arkoub R, Sun S, Hiremath S, Reunov A, McCormick B*, Ruzicka M*, Burger D*+ (2017) “Microparticle formation in peritoneal dialysis: a proof of concept study”. Can J Kid Health Dis 4: 1-8.

3. Lytvyn Y, Xiao F, Perkins BA, Kennedy CR, Reich HN, Scholey JW, Cherney DZ, Burger D+ (2017) “Assessment of Urinary Microparticles in Normotensive Patients with Type 1 Diabetes”. Diabetologia, 60(3) 581-584.

4. Olsen MH, Angell SY, Asma S, Boutouyrie P, Burger D, Chirinos JA, Damasceno A, Delles C, Giminez-Roqueplo A, Hering D, López-Jaramillo P, Martinez F, Perkovic V, Rietzschel ER, Schillaci G, Schutte AE, Scuteri A, Sharman JE, Wachtell K, Wang JG (2016) “A call to action and a life-course strategy to address the global burden of raised blood pressure on current and future generations: The Lancet Commission on Hypertension”. Lancet 26;388(10060):2665-2712.

5. Vinas JL, Burger D, Haneef R, Knoll W, Campbell P, Gutsol A, Carter A, Allan DS, Burns KD (2016) “Human endothelial colony forming cell-derived exosomes are enriched in microRNA-486-5p that inhibits hypoxic injury”. Kidney Int Epub ahead of print S0085-2538(16)30353-2).

6. Xiao F, Zimpelmann J, Burger D, Kennedy CRJ, Hebert RL, Burns KD (2016) “Protein kinase C-δ stimulates shedding of angiotensin-converting enzyme 2 from proximal tubular cells”. Front Pharmacol 1;7:146.

7. Burger D+, Turner M, He Y, Touyz RM (2016) “Endothelial microparticle-derived reactive oxygen species: Role in endothelial signaling and vascular function”. Oxidative Medicine and Cellular Longevity 2016:5047954.

8. Burger D+, Erdbrügger U, Burns KD (2015) “Re: Microparticles: markers and mediators of sepsis-induced microvascular dysfunction, immunosuppression, and acute kidney injury”. Kidney Int 88(4): 915. (IF: 8.5).

9. Silver SA, Cardinal H, Colwell K, Burger D, Dickhout J (2015) “Acute kidney injury: preclinical innovations, challenges, and opportunities for translation”. Can J Kidney Health Dis 1(2):30. (IF:NA).

10. Burger D, Viñas JL, Akbari S, Dehak H, Knoll W, Gutsol A, Touyz RM, Allan D, Burns KD (2015) “Human endothelial colony forming cells protect against acute kidney injury”. Am J Pathol 185(8) 2309-2323. (IF: 4.6)
- Article was selected as an editor’s choice for July 2015

11. Nasrallah R, Hassouneh R, Zimpelmann J, Karam AJ, Thibodeau JF, Burger D, Burns KD, Kennedy CR, Hébert RL (2015) “Prostaglandin E2 increases proximal tubule fluid reabsorption, and modulates cultured proximal tubule cell responses via EP1 and EP4 receptors”. Lab Invest 95(9):1044-1055 (IF: 3.7).

12. Veerabhadrappa P, Burger D, Brouwers S, Christofidou P, El Bikai R, Hannah-Schmouni F, Kruger R, Marques FZ, Mian MOR, Montezano AC, Romero CA, Pena-Silva RA, Wainford RD, Charchar FJ, Schutte AE, Tomaszewski M (2015) “Across the globe in four months- two international society of hypertension new investigator symposia in 2014”. J Hypertens 33(4): 891-893. (IF: 4.2)

13. Burger D, Gagnon A, Lochnan HA, Mahzari M, Sorisky A (2015) “In vivo administration of thyroid-stimulating hormone increases levels of circulating microparticles and pro-coagulant activity”. Clin Endocrinol 83(2): 285-287 (IF: 3.4).

14. Thibodeau JF, Holterman CE, Burger D, Read NC, Reudelhuber TL, Kennedy CR (2014) “A novel model of advanced diabetic kidney disease”. PLoS One 16;9(12)e113459 (IF: 3.53).

15. Burger D, Veerabhadrappa P, Charchar F, Schutte AE, Tomaszewski M (2014) “Report of the 3rd Annual International Society of Hypertension New Investigator Symposium”. J Hypertens 32(2):448-449 (IF: 4.2).

16. Schock SC, Edrissi H, Burger D, Cadonic R, Hakim A, Thompson C (2014) “Microparticles generated during chronic cerebral ischemia deliver proapoptotic signals to cultured endothelial cells”. Biochem Biophys Res Commun 451(1) 912-917 (IF: 2.3).

17. Burger D, Reudelhuber TL, Mahajan A, Chibale K, Touyz RM, Sturrock ED (2014) “Effects of a domain selective ACE inhibitor in a mouse model of chronic angiotensin II-dependent hypertension”. Clin Sci 127(1) 57-63 (IF: 5.6).

18. Burger D, Thibodeau JF, Holterman CE, Burns KD, Touyz RM, Kennedy CRJ (2014) “Urinary podocyte microparticles identify pre-albuminuric diabetic glomerular injury”. J Am Soc Nephrol 25(7) 1401-1407 (IF: 9.7).
- Article was highlighted in an editorial by Dr. Kumar Sharma J Am Soc Nephrol (2014).

19. Burger D, Levin A (2013) “ ‘Shedding’ Light on Mechanisms of Hyperphosphatemic Vascular Dysfunction”. Kidney Int 83(2) 187-189 (IF: 8.5).

20. Burger D+, Schock S, Thompson CS, Montezano AC, Hakim AM, Touyz RM (2013) “Microparticles: Biomarkers and Beyond”. Clin Sci 124(7) 423-441 (IF: 5.6).
- Article was featured on the cover of the April 2013 issue

21. Sedeek M, Gutsol A, Montezano AC, Burger D, Nguyen Dinh Cat A, Kennedy C.R.J, Burns KD, Cooper M, Jandeleit-Dahm K, Page P, Szyndralewiez C, Heitz F, Hebert RL, Touyz RM (2012) “Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of type 2 diabetes”. Clin Sci 124(3) 191-202 (IF: 5.6).

22. Briones AM *, Nguyen Dinh Cat A *, Callera GE, Yogi A, Burger D, He Y, Correa JW, Gagnon AM, Gomez-Sanchez CE, Gomez-Sanchez EP, Sorisky A, Ooi TC, Ruzicka M, Burns KD, Touyz RM (2012) “Adipocytes Produce Aldosterone Through Calcineurin/NFAT-Dependent Signaling Pathway – Implications in Diabetes-Associated Obesity”. Hypertension 59(5) 1069-1078 (IF: 7.6). *Equal contribution to this work.

23. Burger D*, Kwart DG*, Montezano AC, Read NC, Kennedy CRJ, Thompson CS, Touyz RM (2012) “Microparticles Induce Cell Cycle Arrest Through Redox-Sensitive Processes in Endothelial Cells: Implications in Vascular Senescence”. J Am Heart Assoc 1:e001842 (IF: 4.3). * Equal contribution to this work .
- Article was identified the 5th most read original research article in J Am Heart Assoc (May 2012)

24. Burger D, Gutsol A, Carter A, Allan D, Touyz RM, Burns KD (2012) “Human Cord Blood CD133+ Cells Exacerbate Ischemic Acute Kidney Injury in Mice”. Nephrology Dialysis Transplantation 27(10) 3781-3789 (IF: 3.5).
- Article was featured in an editorial by Dr. Duska Dragun: Nephrol Dial Transplant (2012) 27: 3683–3685

25. Veerabhadrappa P, Charchar F, Burger D, Tomaszewski M, Carlberg B (2012) “Leading the Change: Second International Society of Hypertension New Investigators’ Symposium”. J Hypertens 31(2) 429-430 (IF: 4.2).

26. Nguyen Dinh Cat A, Montezano AC, Burger D, Touyz RM (2012) “Angiotensin II, NADPH Oxidase and Redox Signaling in the Vasculature”. Antioxid Redox Signal 19 (10) 1110-1120 (IF: 7.7).

27. Burger D+, Veerabhadrappa P, Carlberg B, Charchar F, Tomaszewski M, Harrap S, Touyz RM (2012) “Report of the 1st ISH Trainee/New Investigator Symposium- A Global Hypertension Initiative”. J Hypertens 30 (3) 631-632 (IF: 4.2).

28. Veerabhadrappa P, Burger D, Carlberg B, Charchar F, Tomaszewski M, Harrap S, Touyz RM (2012) “Council for High Blood Pressure Research/InterAmerican Society of Hypertension/International Society of Hypertension-First New Investigators Symposium at the High Blood Pressure Research 2011 Scientific Sessions”. Hypertension 59(2) 382-383 (IF: 7.6).

29. Burger D+, Touyz RM (2012) “Cellular Biomarkers of Endothelial Health: Microparticles, Endothelial Progenitor Cells, and Circulating Endothelial Cells”. J Am Soc Hypertens 6(2) 85-99 (IF: 2.7).
- Article was highlighted in an editorial by Dr. Myron H. Weinberger

30. Burger D, Montezano AC, Nishigaki N, Touyz RM (2011) “Endothelial Microparticle Formation by Ang II is Mediated by AT1R/NADPH oxidase/Rho kinase Pathways Targeted to Lipid Rafts”. Arterioscler Thromb Vasc Biol 31(8) 1898-1907 (IF: 5.5).

31. Burger D, Feng Q (2011) “Protective Role of Nitric Oxide Against Cardiac Arrhythmia- An Update”. The Open Nitric Oxide Journal 3(Suppl 1-M6) 38-47 (IF: NA).

32. Veerabhadrappa P, Burger D, Carlberg B, Charchar F, Tomaszewski M, Harrap S (2011) “ISH Hypertension Future Leaders Group: a Network for New Investigators Run by New Investigators”. J Hypertens 29(8) 1664-1665 (IF: 4.2).

33. Savoia C, Burger D, Nishigaki N, Montezano AC, Touyz RM (2011) “Angiotensin II and the Vascular Phenotype in Hypertension”. Expert Rev Mol Med (13) e11 (IF: 5.9).

34. Montezano AC, Zimmerman D, Yusuf H, Burger D, Chignalia AZ, Wadhera V, Van Leeuwen FN, Touyz RM (2010) “Vascular Smooth Muscle Cell Differentiation to an Osteogenic Phenotype Involves TRPM7 - Modulation by Magnesium”. Hypertension 56(3) 453-462 (IF: 7.6).

35. Montezano AC, Burger D, Paravicini TM, Chignalia AZ, Yusuf H, Almasri M, He Y, Callera GE, He G, Krause KH, Lambeth D, Quinn MT, Touyz RM (2010) “Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 5 (Nox5) Regulation by Angiotensin II and Endothelin-1 is Mediated via Calcium/Calmodulin-dependent, Rac-1-Independent Pathways in Human Endothelial Cells”. Circ Res 106(8) 1363-1373 (IF: 11.1).

36. Touyz RM, Briones AM, Sedeek M, Burger D, Montezano AC (2010) “Nox Isoforms and Reactive Oxygen Species in Vascular Health”. Mol Interv (1) 27-35 (IF: NA).

37. Montezano AC, Burger D, Ceravolo GS, Yusuf H, Montero M, Touyz RM (2010) “Novel Nox Homologues in the Vasculature: Focusing on Nox4 and Nox5”. Clin Sci 120 (4) 131-141 (IF: 5.6).

38. Burger D, Nishigaki N, Touyz RM (2010) “New Insights into Molecular Mechanisms of Hypertension”. Curr Opin Nephrol Hypertens 19(2) 160-162 (IF: 4.23).

39. Burger DE*, Lu X*, Lei M, Xiang F, Hammoud L, Jiang M, Wang H, Jones DL, Sims SM, Feng Q (2009) “Neuronal Nitric Oxide Synthase Protects Against Myocardial Infarction-Induced Ventricular Arrhythmia and Mortality in Mice”. Circulation 120(14) 1345-1354 (IF: 15.3). *Equal contribution to this work.
- Article was selected as an Editor’s Choice in Circulation for 2009-2010.

40. Burger DE, Xiang FL, Hammoud L, Jones DL, Feng Q (2009) “Erythropoietin Protects the Heart from Ventricular Arrhythmia During Ischemia and Reperfusion via Neuronal Nitric Oxide Synthase”. J Pharmacol Exp Ther 329(3) 900-907 (IF: 3.9).

41. Hammoud L, Burger D, Lu X and Feng Q. (2009) “Tissue Inhibitor of Metalloproteinase-3 Inhibits Neonatal Mouse Cardiomyocyte Proliferation via EGFR/JNK/SP-1 signaling”. Am J Physiol Cell Physiol 296(4) C735-C745 (IF: 3.7).

42. Burger D, Xenocostas A, Feng Q (2009) “Molecular Basis of Cardioprotection by Erythropoietin”. Current Mol Pharm 2(1) 56-69 (IF: NA).

43. Burger DE, Xiang F, Hammoud L, Lu X, Feng Q (2009) “Role of Heme Oxygenase-1 in the Cardioprotective Effects of Erythropoietin during Myocardial Ischemia and Reperfusion”. Am J Physiol Heart Circ Physiol 296(1) H84-H93 (IF: 4.0).

44. Geoghegan-Morphet N*, Burger D*, Lu X, Satish V, Peng T, Sims SM, Feng Q (2007) “Role of Neuronal Nitric Oxide Synthase in Lipopolysaccharide-Induced Tumor Necrosis Factor-Alpha Expression in Neonatal Mouse Cardiomyocytes”. Cardiovasc Res 75(2) 408-416 (IF: 5.8). *Equal contribution to this work.

45. Burger D, Lei, M., Geoghegan-Morphet N, Lu X, Xenocostas A, Feng Q (2006) “Erythropoietin Protects Cardiomyocytes from Apoptosis via Up-regulation of Endothelial Nitric Oxide Synthase”. Cardiovasc Res 72(1):51-9 (IF: 5.8).
- Article was identified as one of the top 15 most downloaded manuscripts of 2006 in Cardiovasc Res.
- Article was highlighted in an editorial by Dr. Joachim Fandry Cardiovasc Res 72(1) 1-2.

46. Lepic E, Burger D, Lu X, Song W, Feng Q (2006) “Lack of Endothelial Nitric Oxide Synthase Decreases Cardiomyo'cyte Proliferation and Delays Cardiac Maturation”. Am J Physiol Cell Physiol 291:C1240-C1246 (IF: 3.7).

PubMed Listings

For more publications use this PubMed ID link.