Stuart Coupland
scoupland@ottawahospital.on.ca
Telephone: 613-737-8235
Fax: 613-737-8836
Clinical Investigator, Vision, Ottawa Hospital Research Institute
Associated Scientist Research, University of Ottawa Eye Institute, The Ottawa HospitalAssociate Professor, Department of Ophthalmology, Faculty of Medicine, University of Ottawa
Associate Professor, Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa
Director of Structural and Functional Retinal Imaging Unit, University of Ottawa Eye Institute, The Ottawa Hospital
Biographical Sketch
Stuart G. Coupland completed his PhD in Experimental Psychology at Simon Fraser University in Burnaby, British Columbia, in 1979. Following he was awarded the J.B.R. Cosgrove Research Fellowship at the Montreal Neurological Institute in the Department of Neuro-ophthalmology and with a cross-appointment in the Ophthalmology Department at McGill University. During that time, he was awarded a 3-year postdoctoral fellowship from the Multiple Sclerosis Society of Canada.
In 1982, Dr. Coupland moved to Calgary where he held academic appointments in the Departments of Pediatrics, Clinical Neurosciences and Surgery at the University of Calgary. Dr. Coupland was Director of Sensory Physiology Laboratory at Alberta Children's Hospital for the next 16 years. During that time, he established an active clinical service in auditory, visual and somatosensory evoked potential in assessing neonates and pediatric population in the Pediatric Neurology Department at Alberta Children's Hospital. He also established surgical intraoperative monitoring of patients in the operating room. At that time he had a funded clinical research program in auditory pathway development during the neonatal and perinatal period. He also had a research program in juvenile diabetic retinopathy. In 1994, he became Research Director at the Gimbel Eye Centre, and managed clinical trials activities there in cataract and laser refractive surgery.
In 1998, Dr. Coupland moved to Ottawa where he was appointed in the Department of Ophthalmology at the University of Ottawa and became the Director of Structural and Functional Retinal Imaging Unit at the University of Ottawa Eye Institute. Dr. Coupland's clinical research interests include the investigation of structural and functional correlates in age related macular degeneration and diabetic retinopathy using multifocal electroretinography and optical coherence tomography imaging techniques. His basic research laboratory investigates retinal function in animal models of retinal degeneration and in gene therapy treatment for retinal diseases. Dr. Coupland has had medical research funding from the Canadian Institutes of Health Research (CIHR), Foundation for Fighting Blindness (FFB), Canadian National Institute for the Blind (CNIB), Juvenile Diabetes Foundation, Multiple Sclerosis Society of Canada, and the Alberta Heritage Foundation for Medical Research. Dr. Coupland has had numerous grants and contract support from pharmaceutical companies and biomedical instrument manufacturers and is consulting in international multicentre clinical trials. Dr. Coupland has developed the first North American reading centre for visual electrodiagnostics at the University of Ottawa Eye Institute, which has provided ERG reading for numerous US and international clinical trials.
Research Interests
- Imaging of retinal structure and function in patients undergoing clinical trials to assess new treatments and monitor retinal safety
- Imaging of retinal structure and function in animal models to investigate novel compounds for treating eye disease
1979 - The J.B.R. Cosgrove Research Fellowship, Montreal Neurological Institute
1980-1982 - The Multiple Sclerosis Society of Canada Fellowship
2005 - The American Academy of Ophthalmology Achievement Award
Current Funding
CIHR
Diagnosys LLC
Most Recent Publications (provided by The Ottawa Hospital Library Database)
Coupland SG;, (2010), Pattern Electroretinogram and Psychophysical Tests of Visual Function for Discriminating between Healthy and Glaucoma Eyes., Evidence-Based Ophthalmology, Vol.11, Issue 4, 204-205
Brodbaker E;Al Karmi R;Hurley B;Coupland SG;, (2010), The Novel Use of Bevacizumab and Photodynamic Therapy in the Treatment of Best Disease., Retinal Cases & Brief Reports, Vol.4, 194-197
Medina CF;Mazerolle C;Wang Y;Berube NG;Coupland S;Gibbons RJ;Wallace VA;Picketts DJ;, (2009 Mar 1), Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome, Human Molecular Genetics, Vol.18, Issue 5, 966-977 -> view abstract
Cordell WH;Maturi RK;Costigan TM;Marmor MF;Weleber RG;Coupland SG;Danis RP;McGettigan JW;Antoszyk AN;Klise S;Sides GD;ERG Testing During Chronic PDE;, (2009 Apr), Retinal effects of 6 months of daily use of tadalafil or sildenafil, Archives of Ophthalmology, Vol.127, Issue 4, 367-373 -> view abstract
Costello F;Hodge W;Pan YI;Eggenberger E;Coupland S;Kardon RH;, (2008 Aug), Tracking retinal nerve fiber layer loss after optic neuritis: a prospective study using optical coherence tomography, Mult Scler , Vol.14, Issue 7, 893-905 -> view abstract
Campbell RJ;Coupland SG;Buhrmann RR;Kertes PJ;, (2007 May), Optimal optical coherence tomography-based measures in the diagnosis of clinically significant macular edema: retinal volume vs foveal thickness, Archives of Ophthalmology, Vol.125, Issue 5, 619-623
Campbell RJ;Coupland SG;Buhrmann RR;Kertes PJ;, (2007 May), Effect of eccentric and inconsistent fixation on retinal optical coherence tomography measures, Archives of Ophthalmology, Vol.125, Issue 5, 624-627
Sheikh A;Hodge W;Coupland S;, (2007 Jul), Diode laser-induced uveitis and visual field defect, Ophthalmic Plastic & Reconstructive Surgery, Vol.23, Issue 4, 321-323 -> view abstract
Leonard KC;Petrin D;Coupland SG;Baker AN;Leonard BC;LaCasse EC;Hauswirth WW;Korneluk RG;Tsilfidis C;, (2007), XIAP protection of photoreceptors in animal models of retinitis pigmentosa, PLoS ONE [Electronic Resource], Vol.2, e314
Costello F;Coupland S;Hodge W;Lorello GR;Koroluk J;Pan YI;Freedman MS;Zackon DH;Kardon RH;, (2006 Jun), Quantifying axonal loss after optic neuritis with optical coherence tomography, Annals of Neurology, Vol.59, Issue 6, 963-969 -> view abstract
