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Associate Scientist, Regenerative Medicine, Ottawa Hospital Research Institute
Biographical Sketch (or Research)
My research interest is in data mining and computational genomic analysis applied to human disease.
Selected Publications
Pratt MA, Tibbo E, Robertson SJ, Jansson D, Hurst K, Perez-Iratxeta C, Lau R, Niu MY. The canonical NF-kappaB pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population. Oncogene. 2009 28(30):2710-22.
Perez-Iratxeta C, Andrade-Navarro MA. K2D2: estimation of protein secondary structure from circular dichroism spectra. BMC Struct Biol. 13; 8:25.
Perez-Iratxeta, C., Palidwor, G and Andrade-Navarro MA. 2007. Towards completion of the Earth's proteome. EMBO reports, 8, 12, 1135-1141. [PMID: 18059312]
Perez-Iratxeta, C., P. Bork and M.A. Andrade-Navarro. 2007. Update of the G2D tool for prioritization of gene candidates to inherited diseases. Nucleic Acids Research. 35:W212. [PMID: 17478516]
Perez-Iratxeta, C., M.A. Andrade-Navarro and J.D. Wren. 2006. Evolving research trends in bioinformatics. Briefings in Bioinformatics. 8:88-95. [PMID: 17077138]
Tiffin, N., E. Adie, F. Turner, H.G. Brunner, M.A. van Driel, M. Oti, N. Lopez-Bigas, C. Ouzounis, C. Perez-Iratxeta, M.A. Andrade-Navarro, A. Adeyemo, M.E. Patti, C. Semple and W. Hide. 2006. Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes. Nucleic Acids Research. 34:3067-3081 [PMID: 16757574]
Perez-Iratxeta, C. & Andrade, M.A. (2005).Inconsistencies over time in 5% of NetAffx probe-to-gene annotations. BMC Bioinformatics, 6, 183. [PMID: 16033654]
Perez-Iratxeta, C., Wjst, M., Bork, P. & Andrade, M.A. (2005). G2D: a tool for mining genes associated with disease. BMC Genetics, 6, 45. [PMID: 16115313]
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