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Senior Scientist, Regenerative Medicine, Ottawa Hospital Research Institute
Assistant Professor, Biochemistry,
University of Ottawa
Research Interests
My research interests are 1. to
elucidate the molecular mechanisms underlying formation of the
epidermis of mouse skin, and 2. to understand how these processes
go awry in skin diseases.
Major Research Activities
1.how growth factors regulate the
commitment of epidermal progenitors in the differentiating
embryonic stem (R1) cells,
2. identifying and characterizing
genes that determine the pathway leading from very early
progenitors (K8-positive) to late epidermal progenitors
(K5/K14-positive), using the gene trap and differential display
techniques.
Recent Publications:
Most Recent Publications (provided by The Ottawa Hospital Library Database)
Jezierski A;Gruslin A;Tremblay R;Ly D;Smith C;Turksen K;Sikorska M;Bani-Yaghoub M;, (2010 Mar 11), Probing Stemness and Neural Commitment in Human Amniotic Fluid Cells, Stem Cell Rev, -> view abstract
Turksen K;, (2010 Jan), Wasted salts and wasted bodies: new insight into the role of claudin 7 in the kidney, American Journal of Physiology - Renal Physiology, Vol.298, Issue 1, F22
Arabzadeh A;Troy TC;Turksen K;, (2009 Nov), Insights into the role of the calcium sensing receptor in epidermal differentiation in vivo, Mol Biotechnol , Vol.43, Issue 3, 264-272 -> view abstract
Troy TC;Arabzadeh A;Lariviere NM;Enikanolaiye A;Turksen K;, (2009), Dermatitis and aging-related barrier dysfunction in transgenic mice overexpressing an epidermal-targeted claudin 6 tail deletion mutant, PLoS ONE, Vol.4, Issue 11, e7814 -> view abstract
Arabzadeh A;Troy TC;Turksen K;, (2008 Jan), Claudin expression modulations reflect an injury response in the murine epidermis, Journal of Investigative Dermatology, Vol.128, Issue 1, 237-240 -> view abstract
Turksen K;, (2008), Reviewing stem cells: a new day, Stem Cell Reviews, Vol.4, Issue 1, 1 -> view abstract
Troy TC;Arabzadeh A;Enikanolaiye A;Lariviere N;Turksen K;, (2008), Immunohistochemistry on paraffin sections of mouse epidermis using fluorescent antibodies, Journal of Visualized Experiments, Vol.-11, Issue 8-Jan, pii:552 -> view abstract
Troy TC;Arabzadeh A;Yerlikaya S;Turksen K;, (2007 Nov), Claudin immunolocalization in neonatal mouse epithelial tissues, Cell Tissue Res, Vol.330, Issue 2, 381-388 -> view abstract
Troy TC;Turksen K;, (2007 Jun), The targeted overexpression of a Claudin mutant in the epidermis of transgenic mice elicits striking epidermal and hair follicle abnormalities, Molecular Biotechnology, Vol.36, Issue 2, 166-174 -> view abstract
Troy TC;Li Y;O'Malley L;Turksen K;, (2007 Feb), The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice., Gene Expression Patterns, Vol.7, Issue 4, 423-430 -> view abstract
Books
Turksen, K. (Editor). Embryonic Stem Cell Protocols Volume I: Isolation And Characterization (Methods in Molecular Biology). 2006. Humana Press.
Turksen, K. (Editor). Embryonic Stem Cell Protocols Volume II: Differentiation Models (Methods in Molecular Biology). 2006. Humana Press.
Turksen, K. (Editor). Human Embryonic Stem Cell Protocols (Methods in Molecular Biology). 2006. Humana Press.
Note: This is not a complete list of publications. More publications may be available in The Ottawa Hospital Library database and Pubmed (search by last name and initials).
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