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Senior Scientist, Chronic Disease, Ottawa Hospital Research Institute
Assistant Professor, Biochemistry,
University of Ottawa
Research Interests
My research interests are 1. to
elucidate the molecular mechanisms underlying formation of the
epidermis of mouse skin, and 2. to understand how these processes
go awry in skin diseases.
Major Research Activities
1.how growth factors regulate the
commitment of epidermal progenitors in the differentiating
embryonic stem (R1) cells,
2. identifying and characterizing
genes that determine the pathway leading from very early
progenitors (K8-positive) to late epidermal progenitors
(K5/K14-positive), using the gene trap and differential display
techniques.
Recent Publications:
Most Recent Publications (provided by The Ottawa Hospital Library Database)
Arabzadeh A;Troy TC;Turksen K;, (2008 Jan), Claudin expression modulations reflect an injury response in the murine epidermis, Journal of Investigative Dermatology, Vol.128, Issue 1, 237-240 -> view abstract
Troy TC;Arabzadeh A;Enikanolaiye A;Lariviere N;Turksen K;, (2008), Immunohistochemistry on paraffin sections of mouse epidermis using fluorescent antibodies, Journal of Visualized Experiments, Vol.-11, Issue 8-Jan, pii:552 -> view abstract
Turksen K;, (2008), Reviewing stem cells: a new day, Stem Cell Reviews, Vol.4, Issue 1, 1 -> view abstract
Troy TC;Turksen K;, (2007 Jun), The targeted overexpression of a Claudin mutant in the epidermis of transgenic mice elicits striking epidermal and hair follicle abnormalities, Molecular Biotechnology, Vol.36, Issue 2, 166-174 -> view abstract
Troy TC;Li Y;O'Malley L;Turksen K;, (2007 Feb), The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice., Gene Expression Patterns, Vol.7, Issue 4, 423-430 -> view abstract
Troy TC;Turksen K;, (2006), Derivation of epidermal colony-forming progenitors from embryonic stem cell cultures, Methods in Molecular Biology, Vol.330, 93-104 -> view abstract
Troy TC;Turksen K;, (2006), Directing epidermal fate selection by a novel co-culture system, Methods in Molecular Biology, Vol.330, 105-11 -> view abstract
Turksen K;Troy TC;, (2006), Human embryonic stem cells: isolation, maintenance, and differentiation. [Review] [45 refs], Methods in Molecular Biology, Vol.331, 1-12 -> view abstract
Troy TC;Rahbar R;Arabzadeh A;Cheung RM;Turksen K;, (2005 Jun), Delayed epidermal permeability barrier formation and hair follicle aberrations in Inv-Cldn6 mice, Mech Dev , Vol.122, Issue 6, 805-819 -> view abstract
Troy TC;Turksen K;, (2005 Feb), Commitment of embryonic stem cells to an epidermal cell fate and differentiation in vitro, Developmental Dynamics, Vol.232, Issue 2, 293-300 -> view abstract
Books
Turksen, K. (Editor). Embryonic Stem Cell Protocols Volume I: Isolation And Characterization (Methods in Molecular Biology). 2006. Humana Press.
Turksen, K. (Editor). Embryonic Stem Cell Protocols Volume II: Differentiation Models (Methods in Molecular Biology). 2006. Humana Press.
Turksen, K. (Editor). Human Embryonic Stem Cell Protocols (Methods in Molecular Biology). 2006. Humana Press.
Note: This is not a complete list of publications. More publications may be available in The Ottawa Hospital Library database and Pubmed (search by last name and initials).
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