Chronic Disease Program

News


Enzyme could help develop better approaches to prevent chronic kidney disease
March 1, 2019 - An enzyme called Nox5 may help researchers develop new approaches to prevent chronic kidney disease in people with diabetes or high blood pressure, according to a study published in Antioxidants and Redox Signalling.
Researchers to advance science and improve health with new CIHR funding
February 14, 2019 - Researchers at The Ottawa Hospital, affiliated with the University of Ottawa, are playing a lead role in nine new projects funded by the Canadian Institutes of Health Research (CIHR). These projects will advance science and improve health in ...
How “exosomes” target injured kidney cells and bring them back to life
December 20, 2018 - The kidneys are one of the most sensitive organs in the body. They are often the first to shut down during a critical illness like septic shock and the last to come back (if they come back at all). Dr. Kevin Burns and his team previously found ...
Experimental contraceptive could give women the power to prevent pregnancy and STIs
November 30, 2018 - While condoms are the gold standard for preventing pregnancy and Sexually Transmitted Infections (STIs), there is a need around the world for solutions that can be used independently by women. New research led by Dr. Nongnuj Tanphaichitr brings a ...
Depression linked to “junk DNA” in the serotonin receptor gene
November 21, 2018 - The human genome is thought to be 75 to 90 percent meaningless “junk DNA”, but researchers are increasingly finding that some of this junk may actually do something important. For example, new research led by Dr. Paul Albert and Dr. Eitan ...
Researchers get $788,000 boost from NSERC
November 21, 2018 - Four scientists from The Ottawa Hospital, affiliated with the University of Ottawa, were successful in the recent discovery grant competition from the Natural Sciences and Engineering Research Council of Canada (NSERC). Dr. Barbara Vanderhyden ...
Chance discovery linking diet to type 1 diabetes started whole new field of research
October 22, 2018 - In the early 1980's, Dr. Fraser Scott was conducting nutritional studies on rats that were supposed to develop type 1 diabetes—except they didn't. He discovered that changing the diet of these diabetes-prone rodents had prevented the disease. ...
New research sinks lipid raft concept
October 17, 2018 - Lipid rafts are in every cell biology text book, but new research led by Dr. Xiaohui Zha shows that they probably don’t exist in most real cells. Originally described in the 1980s, lipid rafts were thought to be semi-rigid blocks of cholesterol, ...
Researchers awarded $1.7 M to tackle stroke and heart attack from multiple angles
October 2, 2018 - Five groups from The Ottawa Hospital, affiliated with the University of Ottawa, were successful in the Heart and Stroke Foundation's recent grant competition. Drs. Dar Dowlatshahi, Tim Ramsay and Elizabeth Rochon were awarded $290,000* to test ...
How does type 1 diabetes start? New research implicates early metabolic defects in the pancreas
September 6, 2018 - Type 1 diabetes (T1D) is often diagnosed in the teenage years, but the disease process probably starts much earlier. New research led by Dr. Fraser Scott shows that cellular stress is linked to decreased insulin and increased glucagon production ...

2018


July 24, 2018 -  Nerve cell structure plays a major role in kidney function
January 30, 2018 -  The Ottawa Hospital awarded $12.7M for research, double the national CIHR success rate

2017


December 18, 2017 -  Using viruses to fight viruses: new approach eliminates “dormant” HIV-infected cells
November 16, 2017 -  Female reproductive disorder may be linked to problems with hormone recycling
October 26, 2017 -  From tragedy to triumph: scientist makes major discovery about cholesterol while recovering from stroke
October 24, 2017 -  New blood sugar monitoring a game-changer for pregnant women with type 1 diabetes
September 12, 2017 -  Research reveals why our cells make more cholesterol and fat after a big meal
August 17, 2017 -  HIV kept at bay with single injection every 8 weeks
April 7, 2017 -  Research sheds light on how testosterone regulates female reproduction
February 2, 2017 -  Could tiny bits of kidney cells in the urine be a potential warning sign of kidney disease?

2016


October 12, 2016 -  Early-career researchers bring fresh perspective to challenge of high blood pressure
October 5, 2016 -  New role for a famous gene? PCSK9 may control the birth of new fat cells
September 7, 2016 -  Dr. Paul MacPherson awarded Research Chair in Gay Men’s Health from Ontario HIV Treatment Network
September 7, 2016 -  Researchers at The Ottawa Hospital awarded $472,000 by Ontario Research Fund
July 27, 2016 -  Researchers find compound that can protect mice from Ebola
May 4, 2016 -  Cardiovascular researchers get $1.2M boost from Heart and Stroke Foundation
February 24, 2016 -  Could a bacteria-killing protein lead to a new treatment for diabetes?
February 17, 2016 -  Protein fights traffic jams in ALS cells

2015


October 22, 2015 -  Drugs commonly used in kidney transplant patients not as effective as previously thought
September 16, 2015 -  Dr. Greg Knoll awarded $3.9 million to create and translate knowledge in kidney transplantation
September 2, 2015 -  Harnessing the power of the bruise to prevent autoimmune diabetes
August 26, 2015 -  Novel genetic variant affects inflammation and may increase heart disease risk by 50%
August 21, 2015 -  New chair in spinal cord research brings hope for more first steps
August 5, 2015 -  Dr. Dylan Burger awarded $192,000 to study microparticles in kidney and vascular disease
July 28, 2015 -  The Ottawa Hospital awarded $28M from Canadian Institutes of Health Research for 22 research projects
June 24, 2015 -  Putrescine water doubles fertility in aging females
June 10, 2015 -  How does the liver affect the immune system? $175,000 grant to help find answers
May 27, 2015 -  eConsult reduces wait times and gets high marks from primary care providers
February 11, 2015 -  Researchers find new therapy benefits stroke patients
February 10, 2015 -  Tender Loving Research improving care for people with infectious diseases

2014


November 19, 2014 -  Are your fat cells healthy or are they bloated and causing health problems?
April 14, 2014 -  First Canadian journal dedicated to kidney disease is launched
April 11, 2014 -  East meets West in Ottawa for research symposium
January 8, 2014 -  Thank you SIRT1: How the body adapts to a high-fat diet to prevent metabolic syndrome

2013


December 11, 2013 -  Compounds derived from red wine, spicy peppers and tree bark hold potential for treating ovarian cancer
December 5, 2013 -  The Ottawa Hospital appoints prestigious kidney research chair
November 28, 2013 -  Ottawa researchers to play major role in $8.7M research project aimed at curing HIV
November 20, 2013 -  New lead in the fight against type 1 diabetes
August 23, 2013 -  Dr. Hsiao-Huei Chen discovers a new molecular pathway that controls appetite, metabolism and weight gain
April 22, 2013 -  New program to enhance the survival and quality of life of Canadians needing organ and tissue transplants

2012


November 26, 2012 -  Putrescine water may be Fountain of Youth for eggs
June 21, 2012 -  Blood test for pregnant women could predict risk of having dangerously small babies

2011


December 16, 2011 -  Ottawa research could reduce use of unnecessary medications in people with HIV
November 23, 2011 -  New research sheds light on molecular pathways involved in resistance to chemotherapy in ovarian cancer cells
October 2, 2011 -  New research sheds light on the role of our molecular recycling centres in genetic diseases and male infertility
August 24, 2011 -  Research leads to new insights into mammalian fertilization
April 20, 2011 -  Another great year for the Kidney Research Centre
April 20, 2011 -  New research sheds light on “asymmetric” cell division
April 7, 2011 -  Dr. Benjamin Tsang receives OCRI Research Award

2010


December 25, 2010 -  International study helps identify high risk pregnancies earlier
December 3, 2010 -  Prestigious honour for kidney research
November 24, 2010 -  Possible new strategy to reduce cholesterol
November 9, 2010 -  Ottawa scientist receives $100,000 Grand Challenges Explorations Grant for innovative global health research

2009


August 20, 2009 -  A clue to the elusive cause of type 1 diabetes: Ottawa researchers investigate immune response to wheat
May 29, 2009 -  Dr. Michel Chrétien elected Fellow of the Royal Society of London

2008


October 29, 2008 -  OHRI students organize CIHR Café Scientifique on HIV / AIDS prevention
October 7, 2008 -  Special honour for Dr. Michel Chrétien
January 1, 2008 -  Dr. Rhian Touyz is investigating molecular changes in blood vessels that may contribute to hypertension

2007


May 3, 2007 -  Grand opening of the Kidney Research Centre

2006


December 4, 2006 -  Ottawa study reveals “normal” form of the prion protein associated with neurodegenerative diseases could have role in blood sugar regulation
August 1, 2006 -  Dr. Kursad Turksen’s research on skin cells may lead to new ways to protect premature babies, promote wound-healing, and treat various skin disorders
March 31, 2006 -  Fighting back: HIV is deadly because it destroys the immune system.
But Dr. Paul MacPherson is looking for ways to help the immune system fight back.