Recent Publications:

Thrombosis Researcher Publications

2009 Publications

Wells PS, Le Gal G, Tierney S, Carrier M. Practical application of the 10-mg warfarin initiation nomogram. Blood Coag Fibrinolysis 2009; 20:403-408.

Douma RA, Gibson NS, Gerdes VEA, Perrier A, Buller HR, Wells PS, Perrier A, Le Gal G. Validity and clinical utility of the simplified Wells rule for assessing clinical probability for the exclusion of  pulmonary embolism. Thromb Haemost 2009;101:197-200.

Louzada ML, Majeed H, Wells PS. Efficacy of low-molecular-weight heparin versus Vitamin K antagonists for long term treatment of cancer-associated venous thromboembolism in adults: a systematic review of randomized controlled trials. Thromb Res 2009;123:837-844.

Dao V, Rodger MA. Anticoagulants to prevent placenta-mediated pregnancy complications: a review of current evidence Current Opinion in Hematology 2009;16:386-390.

Lazo-Langner A, Rodger MA. Lessons from Ximelagatran.  Issues for future studies evaluating new oral direct thrombin inhibitors for venous thromboembolism prophylaxis in orthopaedic surgery.  Clin Appl Thromb Hemost 2009;15(3):316-326.

Chan W-S, Lee A, Spencer FA, Crowther M, Rodger MA, Ginsberg JS Predicting DVT in Pregnancy: Out in “Left” Field? Ann Intern Med 2009;151:85-92.

Lazo Langner A, Rodger M. Overview of Current Venous Thromboembolism Protocols in Hip Reconstruction Orthop Clin N Am 40:(2009);427-436.

Rodger MA.  Thrombophilia and Placenta Mediated Pregnancy Complications: From the Bench to Bedside to Policy Thromb Res 2009;123 Suppl 2:5100-4.

Oake N, Forster A, Van Walraven C, Rodger MA.The effect of an interactive voice response system on oral anticoagulant management. CMAJ January 2009:180(9):927-933.

Le Gal G, Kovacs M, Carrier M, Do K, Kahn SR, Wells PS, Anderson DA, Chagnon I, Solymoss S, Crowther M, Righini M, Perrier A, White RH, Vickars L, Rodger M. Validation of a diagnostic approach to exclude recurrent venous thromboembolismThromb Haemost 2009 May;7(5):752-9.

Le Gal G, Carrier M, Righini M, Karami-Djurabi R, Huisman MV, Perrier A, Wells PS, Rodger M, Wuillemin WA.  VIDAS® D-dimer in combination with clinical pre-test probability to rule out pulmonary embolism. A systematic review of management outcome studies Thromb  Haemost 2009;101:886-892.

Carrier M, Lee A, Le Gal G, Tierney S, Rodger M. Dose Escalation of Low Molecular Weight Heparin to Manage Recurrent Venous Thromboembolic Events Despite Systematic Anticoagulation in Cancer Patients JTH January 2009;7(5):760-765.

Crowther MA, Ageno W, Garcia D, Wang L, Witt DM, Clark NP, Blostein M, Kahn SR, Schulman S, Kovacs M, Wells P, Anderson D, Kearon C, Ginsberg J, Selby R, Siragusa S, Silingardi M, Dowd MB, Rodger M. Oral vitamin K does not significantly reduce bleeding in excessively anticoagulated patients on Warfarin. Results of a randomized, controlled trial. Ann Intern Med 2009;150(5):293-300.

Rey E, Kahn S, Magee L, Rodger M. Dalteparin for the prevention of recurrence of placental-mediated complications of pregnancy in women without thrombophilia: a pilot randomized controlled trial J Thromb Haemost 2009;7(1):58-64.

2008 Publications

Harrison MB, Graham ID, Lorimer K, VandenKerkof E, Buchanan M, Wells PS, Brandys T, Pierscianowski T. Nurse clinic versus home delivery of evidence-based community leg ulcer care: A randomized health services trial. BMC Health Services Research 2008;8:243-253.

Gonsalves A, Carrier M, Wells PS, McDiarmid S, Huebsch L, Allan DS. Incidence of symptomatic venous thromboembolism following hematopoietic stem cell transplantation. J Thromb Haemost 2008; 6:1468-1473.

Wells PS. Pulmonary Embolism: a clinician’s perspective. Semin Nucl Med 2008; 38:404-411.

Carrier M., Lee AYY, Bates SM, Anderson DR, Wells PS. Accuracy and usefulness of a clinical prediction rule and D-dimer testing in excluding deep vein thrombosis in cancer patients. Thromb Res 2008; 123:177-183.

Scarvelis D, Palareti G, Toulon P, Wells PS, Wu JR. HemosIL D-dimer HS assay in the diagnosis of deep vein thrombosis and pulmonary embolism. Results of a multicenter management study. J Thromb Haemost 2008; 6:1973-75.

Carrier M, Le Gal G, Bates SM, Anderson DR, Wells PS. D-dimer is useful to exclude deep vein thrombosis in elderly outpatients. J Thromb Haemost 2008;6:1072-76.

Wells PS. Interactions with warfarin. Beware of bruising and major bleeds.Parkhurst Exchange 2008;16(6):56-57.

Stein PD, Sostman HD, Bounameaux H, Buller HR, Chenevert TL, Dalen JE, Goodman LR, Gottschalk A, Hull RD, Leeper KV, Pistolesi M, Raskob GE, Wells PS, Woodard PK. Challenges in the diagnosis and prognosis of acute pulmonary embolism. Am J Med 2008;121:565-571.

Wells PS.  Review: Evidence for the effectiveness of anticoagulation therapy or prophylaxis for VTE in cancer is limited.  ACP Journal Club 2008; 148(3):7.

Etchegary H, Wilson B, Brehaut J, Lott A, Langlois N, Wells PS. Psychosocial aspects of venous thromboembolic disease: An exploratory study. Thromb Res 2008;122(4):491-500.

Gibson NS, Sohne M, Gerdes VE, Bossuyt PM, Wells PS, Buller HR. Further validation and simplification of the Wells clinical decision rule in pulmonary embolism. Thromb Haemost 2008; 99:229-234.

Carrier M, Wells PS. Should we regionalize the management of pulmonary embolism?  CMAJ 2008; 178(1): 58-60.

Heshka J, Palleschi C, Howley H, Wilson B, Wells PS. A Systematic review of perceived risks, psychological and behavioural impacts of genetic testing. Genet Med 2008; 10(1):19-32.

Kearon C, Julian J, Kovacs M, Anderson D, Wells P, MacKinnon B, Weitz J, Dolan S, Crowther M, Geerts W, Turpie G, Solymoss S, van Nguyen P, Demers C, Kahn S, Kassis J, Rodger M, Hambleton J, Gent M, Ginsberg J Influence of thrombophilia on risk of recurrent venous thromboembolism while on warfarin: Results from a randomized trial Blood 2008 Dec 1;112(12):4432-6.

Carrier M, Le Gal G, Wells PS, Fergusson D and Rodger MA Systematic Review: The Trousseau Syndrome Revisited : Should we screen extensively for cancer in patients with venous thromboembolism. Ann Intern Med 2008;149(5):323-333. 

Rodger MA, Kahn SR, Wells PS, Anderson DA, Chagnon I, Le Gal G, Solymoss S, Crowther M, Perrier A, White R, Vickars L, Ramsay T, Betancourt MT, Kovacs MJ Identifying Unprovoked Thromboembolism Patients a Low Risk for Recurrence who can Discontinue Anticoagulant Therapy CMAJ 2008;179(5):417-426.

Heshka J, Dunn C, Wilson B, Brehaut J, Rutberg J, Langlois N, Rodger M, Etchegary H, Wells PS Cognitive and Behavioural Impacts of Genetic Testing for Thrombophilia JOGC 2008 Jun;17(3):288-296.

Rodger MA, Paidas M, McLintock C, Middeldorp S, Kahn S, Martinelli I, Hague W, Rosene Montella K, Greer I Inherited Thrombophilia and Pregnancy Complications Revisited
Obstetrics and Gynecology Vol. 112, No. 2, Part 1, August 2008 Pages 320-324.

Le Templier G, Rodger MA Heparin Induced Osteoporosis in Pregnancy Current Opinion in Pulmonary Medicine 2008;14:403-407.

Rodger MA, Kahn S, Le Gal G, Solymoss S, Chagnon I, Anderson D, Wells P, Kovacs MJ Inter-Observer Reliability of Measures to Assess the Post-Thrombotic Syndrome.  Thromb Haemost 2008:100(1);164-6.

Fergusson DA, Hébert PC, Mazer DC, Fremes S, MacAdams C, Murkin J. Teoh K, Duke PC, Arellano R, Blajchman M, Bussières JS, Côté D, Karski J, Martineau R, Robblee J, Rodger MA, Wells G, Clinch J, Pretorius R for the BART Investigators.A Comparison of Aprotinin and Lysine Analogues in High-Risk Cardiac Surgery NEJM 2008 358(22):2319-2331.

Heshka J, Palleschi C, Wilson B, Brehaut J, Rutbert J, Etchegary H, Langlois N, Rodger M, Wells PS Cognitive and Behavioural Effects of Genetic Testing for Thrombophilia.  J Genet Couns 2008 Feb 21.

Carrier M, Rodger MA, Fergusson D, Doucette S, Kovacs MJ, Moore J, Kelton JG, Knoll GA.Increased mortality in hemodialysis patients having specific antibodies to the platelet factor 4-heparin complex Kidney International 2008;73(2):213-219.

Wen SW, Chen X-K, Rodger MA, Rennicks White R, Yang Q, Smith GN, Sigal RJ, Perkins S, Walker MC.  Folic acid supplementation in early second trimester and the risk of preeclampsia.
AJOG. 2008;198:45.e1-45.e7.