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Depression

The Ottawa Hospital is conducting cutting-edge research to improve our understanding of depression and develop better treatments. This page includes selected news stories about our research related to depression, links to researchers working in this area and related resources. Learn more below.

Research News


Depression linked to “junk DNA” in the serotonin receptor gene
November 21, 2018 - The human genome is thought to be 75 to 90 percent meaningless “junk DNA”, but researchers are increasingly finding that some of this junk may actually do something important. For example, new research led by Dr. Paul Albert and Dr. Eitan Friedman sh
First responders to get mental health help at new research clinic
October 31, 2018 - Recognizing the mental health needs of first responders, the City of Ottawa is championing a new study led by researchers at The Ottawa Hospital and the University of Ottawa. The team will launch Canada’s first research-based mental health clinic for
Antidepressants and exercise in stroke recovery: surprising results from new mouse study
March 2, 2018 - Exercise and selective serotonin reuptake inhibitors (SSRIs) are effective in treating certain kinds of depression, but little research has tested them together in post-stroke depression, which affects 20 to 80 percent of stroke survivors. Drs. Pau
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Albert, Paul
PhD
Senior Scientist
(Neuroscience)
Vascular cognitive impairment, Anxiety, Depression, Intellectual disabilities, Parkinson's, Schizophrenia, Stroke, Suicide Epigenetics, Exercise, Gene expression, Translational research, Disease models, Epigenetics, Genetics, Imaging, Molecular and cellular biology, Optogenetics, Transgenic/knockout models
Chen, Hsiao-Huei
PhD
Senior Scientist
(Neuroscience)
Autism, Depression, Alzheimer's, Alzheimer's, Anxiety, Diabetes, Obesity, Schizophrenia, Stroke, Vascular, heart and metabolic disease Disease models, Gene expression, Optogenetics, Transgenic/knockout models, Basic research, Molecular and cellular biology, Translational research
Hatcher, Simon
BSc MBBS MMedSc MD FRCPC FRANZCP MRCPsych
Scientist
(Clinical Epidemiology)
Anxiety, Brain and neuromuscular disease, First Nations, Inuit and Métis Health, Traumatic brain injury, Depression, Health in disadvantaged peoples, Suicide Clinical research, Health economics, Health professional behaviour change, Health research methods, Health services research, Health technology, Prevention, Qualitative methods, Clinical trials, Cluster randomized trials, Epidemiology, Psychology, Systematic reviews
Hutton, Brian
MSc, PhD
Scientist
(Clinical Epidemiology)
Addiction, Anxiety, Breast cancer, Depression, Cancer Clinical research, Cohort studies, Epidemiology, Health research methods, Patient safety, Public health, Rapid reviews, Biostatistics, Clinical trials, Systematic reviews
MacPherson, Paul
MD/PhD
Scientist
(Clinical Epidemiology)
Anxiety, Depression, Gay men's health, HIV, Infectious disease, Men's health, Sexually transmitted diseases Behaviour, Cohort studies, Epidemiology, Health promotion, Health services research, Knowledge translation and implementation research, Prevention, Psychology, Qualitative methods, Surveys
Poulin, Patricia
C. Psych.
Associate Scientist
(Clinical Epidemiology)
Addiction, Anxiety, Cancer, Chronic pain, Depression, Health equity, Musculoskeletal conditions, Pain Anesthesiology, Behaviour, Biomarkers, Clinical research, Clinical trials, Emergency medicine, Epidemiology, Health professional behaviour change, Health services research, Knowledge translation and implementation research, Palliative care, Patient decision aids, Patient safety, Peri-operative medicine, Pragmatic trials, Psychology, Qualitative methods, Quality Improvement, Systematic reviews
Ramsay, Timothy
PhD
Senior Scientist
(Clinical Epidemiology)
Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, Dystonia, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Santos, Marlise
MD (FRCPC), MSc, MPH
Clinician Investigator
(Clinical Epidemiology)
Alzheimer's, Anxiety, Ataxia, Autoimmune diseases of the nervous system, Brain and neuromuscular disease, Brain cancer, Cancer, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease Basic research, Behaviour, Clinical decision rules, Clinical trials, Cohort studies, Critical care, Drug development, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews, Translational research