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Vascular, heart and metabolic disease

Researchers at The Ottawa Hospital are investigating promising new approaches to prevent, diagnose and treat a wide range of diseases that involve the heart, blood vessels and metabolism. Our work spans the full spectrum of research from basic science to clinical research to implementation.

Research News


Acute kidney injury and chronic kidney disease— newfound hope for treatment
September 12, 2019 - Researchers at The Ottawa Hospital are working together to help prevent and treat acute kidney injury and chronic kidney disease.
Feature grant: Researchers investigate how cholesterol regulates inflammation in white blood cells
August 7, 2019 - Drs. Xiaohui Zha and Alexander Sorisky were awarded $48,000 to test whether cholesterol regulates inflammation in human white blood cells by altering gene expression.
Study establishes long-term risks and consequences of leg vein clot recurrence
July 31, 2019 - Over 750,000 Canadians will have an unexplained vein blood clot in their lifetime, known as venous thrombosis. A collaborative study led by Dr. Marc Rodger and Faizan Khan now provides the best data yet on the long-term risks and consequences of recu
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Allan, David
MD FRCPC
Associate Scientist
(Regenerative Medicine)
Blood cancer, Vascular, heart and metabolic disease Cell therapy, Regenerative medicine, Stem cells, Systematic reviews, Transfusions, Translational research, Transplantation
Brand, Marjorie
PhD
Senior Scientist
(Regenerative Medicine)
Blood cancer, Sickle cell anemia, Thalassemia, Vascular, heart and metabolic disease Basic research, Bioinformatics, Disease models, Epigenetics, Gene expression, Genomics, Imaging, Model organisms, Molecular and cellular biology, Proteomics, Stem cells, Systems biology, Transgenic/knockout models
Burger, Dylan
PhD
Scientist
(Chronic Disease)
Aging, Chronic disease, Diabetes, Kidney disease, Type 1 diabetes, Vascular cognitive impairment, Vascular, heart and metabolic disease Basic research, Biomarkers, Disease models, Imaging, Molecular and cellular biology, Pharmacology, Proteomics, Regenerative medicine, Stem cells, Transgenic/knockout models, Translational research
Burns, Kevin
MD CM, FRCPC
Senior Scientist
(Chronic Disease)
Diabetes, Kidney disease, Vascular, heart and metabolic disease Basic research, Biomarkers, Cell therapy, Clinical research, Disease models, Gene expression, Molecular and cellular biology, Regenerative medicine, Stem cells, Transgenic/knockout models, Translational research
Chen, Hsiao-Huei
PhD
Senior Scientist
(Neuroscience)
Autism, Depression, Alzheimer's, Alzheimer's, Anxiety, Diabetes, Obesity, Schizophrenia, Stroke, Vascular, heart and metabolic disease Disease models, Gene expression, Optogenetics, Transgenic/knockout models, Basic research, Molecular and cellular biology, Translational research
Corrales Medina, Vicente
MD
Associate Scientist
(Clinical Epidemiology)
Pneumonia, Vascular, heart and metabolic disease Clinical research
Fergusson, Dean
PhD, MHA
Program Director and
Senior Scientist
(Clinical Epidemiology)
Cancer, Kidney disease, Septic shock, Vascular, heart and metabolic disease Clinical trials, Health services research, Health technology, Pragmatic trials, Surveys, Translational research, Biostatistics, Clinical research, Cluster randomized trials, Cohort studies, Critical care, Health research methods, Qualitative methods, Quality Improvement, Systematic reviews, Transfusions
Hundemer, Gregory
MD, MPH
Associate Scientist
(Clinical Epidemiology)
Heart disease, Kidney disease, Vascular, heart and metabolic disease Biomarkers, Clinical research, Cohort studies
Klein, Ran
PhD
Clinician Investigator
(Clinical Epidemiology)
Cancer, Heart disease, Vascular, heart and metabolic disease Basic research, Biomarkers, Clinical decision rules, Health technology, Imaging
Lalu, Manoj
MD, PhD, FRCPC
Associate Scientist
(Clinical Epidemiology)
Blood cancer, Heart disease, Stroke, Vascular, heart and metabolic disease Basic research, Cell therapy, Clinical research, Clinical trials, Disease models, Regenerative medicine, Stem cells, Translational research
Manuel, Douglas
MD, MSc, FRCPC
Senior Scientist
(Clinical Epidemiology)
Aging, Alzheimer's, Cancer, Dementia, Diabetes, Frailty, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, Immigrant and refugee health, Infectious disease, Obesity, Parkinson's, Population health, Stroke, Vascular cognitive impairment, Vascular, heart and metabolic disease Big data, Bioinformatics, Biostatistics, Digital and mobile health, Epidemiology, Health research methods, Health services research, Prevention, Public health
Santos, Marlise
MD (FRCPC), MSc, MPH
Clinician Investigator
(Clinical Epidemiology)
Alzheimer's, Anxiety, Ataxia, Autoimmune diseases of the nervous system, Brain and neuromuscular disease, Brain cancer, Cancer, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease Basic research, Behaviour, Clinical decision rules, Clinical trials, Cohort studies, Critical care, Drug development, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews, Translational research
Stanford, William
PhD
Senior Scientist
(Regenerative Medicine)
Aging, Arthritis, Blood cancer, Cancer, Lung cancer, Lymphangioleiomyomatosis (LAM), Osteoporosis, Vascular, heart and metabolic disease Molecular and cellular biology, Regenerative medicine, Stem cells, Systems biology
Stewart, Duncan
MD, FRCPC
Senior Scientist
(Regenerative Medicine)
Heart disease, Pulmonary hypertension, Septic shock, Vascular, heart and metabolic disease Stem cells, Cell therapy, Clinical trials, Molecular and cellular biology, Regenerative medicine, Translational research
Zha, Xiaohui
Ph.D.
Senior Scientist
(Chronic Disease)
Vascular, heart and metabolic disease Molecular and cellular biology