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Vascular, heart and metabolic disease

Researchers at The Ottawa Hospital are investigating promising new approaches to prevent, diagnose and treat a wide range of diseases that involve the heart, blood vessels and metabolism. Our work spans the full spectrum of research from basic science to clinical research to implementation.

Research News


Tiny bits of blood vessel may warn of newborn complications
November 4, 2021 - A study published in Biomarker Research co-led by Drs. Dylan Burger and Denice Feig found that extracellular vesicles may be able to predict newborn outcomes, at least in pregnant people with diabetes.
Study establishes bleeding risk with long-term use of blood thinners for life-threatening clots
October 20, 2021 - A new systematic review and meta-analysis now provides the best data yet on the long-term risks and consequences of bleeding with different blood thinners.
MicroRNA protects mice from acute kidney injury
October 6, 2021 - New research led by Dr. Kevin Burns shows that intravenous delivery of a type of microRNA can protect mice from acute kidney injury, a serious and untreatable condition.
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Allan, David
MD FRCPC
Associate Scientist
(Clinical Epidemiology)
Blood cancer, Vascular, heart and metabolic disease Cell therapy, Regenerative medicine, Stem cells, Systematic reviews, Transfusions, Translational research, Transplantation
Aviv, Richard
MBChB, FRCR (UK), FRCPC, dABR
Clinician Investigator
(Neuroscience)
Brain and neuromuscular disease, Brain cancer, Head and neck cancer, Multiple sclerosis, Stroke, Subarachnoid hemorrhage, Traumatic brain injury, Vascular cognitive impairment, Vascular, heart and metabolic disease 3D printing, Artificial intelligence and data science, Basic research, Big data, Bioinformatics, Biomarkers, Clinical research, Cluster randomized trials, Disease models, Health economics, Health technology, Imaging, Patient safety, Quality Improvement, Translational research
Brand, Marjorie
PhD
Senior Scientist
(Regenerative Medicine)
Blood cancer, Sickle cell anemia, Thalassemia, Vascular, heart and metabolic disease Artificial intelligence and data science, Basic research, Bioinformatics, Disease models, Epigenetics, Gene expression, Genomics, Imaging, Model organisms, Molecular and cellular biology, Proteomics, Stem cells, Systems biology, Transgenic/knockout models
Burger, Dylan
PhD
Senior Scientist
(Chronic Disease)
Aging, Chronic disease, Diabetes, Hypertension, Kidney disease, Type 1 diabetes, Vascular cognitive impairment, Vascular, heart and metabolic disease Basic research, Biomarkers, Disease models, Imaging, Molecular and cellular biology, Pharmacology, Proteomics, Regenerative medicine, Stem cells, Transgenic/knockout models, Translational research
Burns, Kevin
MD CM, FRCPC
Senior Scientist
(Chronic Disease)
Diabetes, Kidney disease, Vascular, heart and metabolic disease Basic research, Biomarkers, Cell therapy, Clinical research, Disease models, Gene expression, Molecular and cellular biology, Regenerative medicine, Stem cells, Transgenic/knockout models, Translational research
Chen, Hsiao-Huei
PhD
Senior Scientist
(Neuroscience)
Aging, Autism, Dementia, Depression, Mental health, Tourette's, Alzheimer's, Alzheimer's, Anxiety, Diabetes, Obesity, Schizophrenia, Stroke, Vascular, heart and metabolic disease Disease models, Gene expression, Optogenetics, Transgenic/knockout models, Basic research, Molecular and cellular biology, Translational research
Corrales Medina, Vicente
MD
Clinician Investigator
(Clinical Epidemiology)
Pneumonia, Vascular, heart and metabolic disease Clinical research
Fergusson, Dean
PhD, MHA, FCAHS
Program Director and
Senior Scientist
(Clinical Epidemiology)
Cancer, COVID-19, Kidney disease, Septic shock, Vascular, heart and metabolic disease Clinical trials, Health services research, Health technology, Patient engagement, Pragmatic trials, Surveys, Translational research, Biostatistics, Clinical research, Cluster randomized trials, Cohort studies, Critical care, Health research methods, Qualitative methods, Quality Improvement, Systematic reviews, Transfusions
Fiedorowicz, Jess
MD, PhD
Scientist
(Clinical Epidemiology)
Bipolar, Mental health, Suicide, Vascular, heart and metabolic disease Clinical research, Epidemiology
Hiremath, Swapnil
MD, MPH, FASN
Associate Scientist
(Clinical Epidemiology)
Chronic disease, Diabetes, Health in older peoples, Heart disease, Hypertension, Kidney disease, Population health, Vascular, heart and metabolic disease Clinical research, Clinical trials, Cohort studies, Epidemiology, Health services research, Imaging, Pharmacology, Pragmatic trials, Public health, Quality Improvement, Systematic reviews
Hundemer, Gregory
MD, MPH
Associate Scientist
(Clinical Epidemiology)
Heart disease, Kidney disease, Vascular, heart and metabolic disease Biomarkers, Clinical research, Cohort studies
Klein, Ran
PhD
Clinician Investigator
(Clinical Epidemiology)
Cancer, Heart disease, Vascular, heart and metabolic disease Artificial intelligence and data science, Basic research, Biomarkers, Clinical decision rules, Health technology, Imaging
Lalu, Manoj
MD, PhD, FRCPC
Associate Scientist
(Clinical Epidemiology)
Blood cancer, COVID-19, Heart disease, Stroke, Vascular, heart and metabolic disease Anesthesiology, Basic research, Cell therapy, Clinical research, Clinical trials, Disease models, Health research methods, Model organisms, Patient engagement, Regenerative medicine, Stem cells, Translational research
Manuel, Douglas
MD, MSc, FRCPC
Senior Scientist
(Clinical Epidemiology)
Aging, Alzheimer's, Cancer, COVID-19, Dementia, Diabetes, Frailty, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, Immigrant and refugee health, Infectious disease, Obesity, Parkinson's, Population health, Stroke, Vascular cognitive impairment, Vascular, heart and metabolic disease Artificial intelligence and data science, Big data, Bioinformatics, Biostatistics, Digital and mobile health, Epidemiology, Health research methods, Health services research, Prevention, Public health
Santos, Marlise
MD (FRCPC), MSc, MPH
Clinician Investigator
(Clinical Epidemiology)
Alzheimer's, Anxiety, Ataxia, Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Brain and neuromuscular disease, Brain cancer, Cancer, Chronic disease, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Sickle cell anemia, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease Artificial intelligence and data science, Basic research, Behaviour, Biostatistics, Cancer biotherapeutics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews
Stanford, William
PhD
Senior Scientist
(Regenerative Medicine)
Aging, Blood cancer, Cancer, COVID-19, Lung cancer, Lymphangioleiomyomatosis (LAM), Vascular, heart and metabolic disease Artificial intelligence and data science, Molecular and cellular biology, Regenerative medicine, Stem cells, Systems biology
Stewart, Duncan
MD, FRCPC
Senior Scientist
(Regenerative Medicine)
COVID-19, Heart disease, Pulmonary hypertension, Septic shock, Vascular, heart and metabolic disease Stem cells, Cell therapy, Clinical trials, Molecular and cellular biology, Regenerative medicine, Translational research
Thiruganasambandamoorthy, Venkatesh
MBBS, CCFP-EM, MSc
Senior Scientist
(Clinical Epidemiology)
Cardiac arrest, COVID-19, Heart disease, Vascular, heart and metabolic disease Artificial intelligence and data science, Clinical decision rules, Clinical research, Emergency medicine, Epidemiology, Health services research
Thornhill, Rebecca
PhD
Clinician Investigator
(Clinical Epidemiology)
Cancer, Heart disease, Stroke, Vascular, heart and metabolic disease Artificial intelligence and data science, Biomarkers, Biostatistics, Imaging, Patient safety
Zha, Xiaohui
Ph.D.
Senior Scientist
(Chronic Disease)
Vascular, heart and metabolic disease Molecular and cellular biology