Success stories: research breakthroughs thanks to StemCore

StemCore is proud to have played a role in many key discoveries at The Ottawa Hospital and the University of Ottawa. Selected success stories are profiled below.

Discovery points to innovative new way to treat Duchenne muscular dystrophy
January 31, 2019 - Researchers at The Ottawa Hospital and the University of Ottawa have discovered a new way to treat the loss of muscle function caused by Duchenne muscular dystrophy in animal models of the disease. As reported in Cell Stem Cell, the team restored mus
New drug combination destroys chemo-resistant blood cancer
October 22, 2018 - Researchers from The Ottawa Hospital and the University of Ottawa have developed a promising targeted strategy to treat chemotherapy-resistant acute myeloid leukemia (AML) and a diagnostic test to determine which AML patients would most likely benefi
Often-overlooked Natural Killer cells may be key to cancer immunotherapy
September 10, 2018 - Immune checkpoint inhibitors are revolutionizing the treatment of cancer, but new research challenges the central dogma of how these drugs work. This research, published in the prestigious Journal of Clinical Investigation, shows for the first time t
How does type 1 diabetes start? New research implicates early metabolic defects in the pancreas
September 6, 2018 - Type 1 diabetes (T1D) is often diagnosed in the teenage years, but the disease process probably starts much earlier. New research led by Dr. Fraser Scott shows that cellular stress is linked to decreased insulin and increased glucagon production in t
$1.7 million to advance research on colon cancer, brain development, kidney disease and severe fluid loss
July 20, 2018 - Four research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $1.7 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). Their projects will advance sci
Estrogen and ovarian cancer: study provides first molecular link
July 11, 2018 - Estrogen therapy can relieve symptoms of menopause in some women, but it also slightly increases the risk of ovarian cancer. New research from Dr. Barbara Vanderhyden's team provides the first possible molecular explanation for this link. Using cells
Researchers uncover possible new mechanism to enhance cancer-killing viruses
July 11, 2018 - Cancer-killing (oncolytic) viruses have shown promise in the lab and the clinic, but they don’t always work. New research led by Dr. Carolina Ilkow could help change this. While normal cells often lose their first line of antiviral defenses when they
$2-million project aims to bring personalized medicine to lung cancer care
October 11, 2016 - A team led by Dr. David Stewart, Dr. Bryan Lo, Dr. Pearl Campbell and Craig Ivany has received $2 million from Genome Canada and partners to develop a test that can better deliver personalized care for patients with non-small cell lung cancer. So