Solving the puzzle of pulmonary arterial hypertension, one cell at a time
October 23, 2025 - What is the best way to complete a jigsaw puzzle? Some might say starting with the corners; others swear by sorting colours and patterns. But there’s one thing everyone can agree on when it comes to seeing the whole picture: all the pieces must be re...

Ottawa Hospital Research Institute and Brain Heart Interconnectome partner to fund brain-heart research scholarship
October 23, 2025 - The Ottawa Hospital Research Institute (OHRI) is partnering with the Brain Heart Interconnectome (BHI) to fund outstanding trainees dedicated to advancing brain-heart research.

MicroRNA for MS: Mouse study sparks potential new treatment approach
June 26, 2025 - It’s easy to forget the delicate balance inside the human body until something goes wrong. For people with multiple sclerosis (MS), that moment comes when the immune system mistakenly attacks myelin—the fatty insulating layer that protects nerve cell...

Why one gene has an outsized impact on neurodevelopmental disorders
February 26, 2025 - “ADNP is a significant gene in neurodevelopmental disorders. With this new tool to study its function, we can work towards finding and testing new treatments."

Researchers discover postal code that allows proteins to hitch a ride around the body
December 11, 2024 - Researchers at The Ottawa Hospital and the University of Ottawa have discovered an 18-digit code that allows proteins to attach themselves to exosomes - tiny pinched-off pieces of cells that travel around the body and deliver biochemical signals.

Lab discovery suggests possible new approach for treating progressive multiple sclerosis
July 26, 2024 - A new study from The Ottawa Hospital and uOttawa shows that a microRNA molecule called miR-145-5p could be key to developing new treatments for progressive multiple sclerosis (MS).

Engineered lung tissue model reveals possible new treatment for lymphangioleiomyomatosis
July 12, 2023 - A research team led by Dr. Bill Stanford has discovered a new class of drugs that may be effective in treating lymphangioleiomyomatosis (LAM). This rare disease is characterized by abnormal cell growth in the lungs which can lead to severe breathing ...

Novel stem cell drives ‘remarkable’ regeneration of tiny blood vessels in the lung
May 15, 2023 - Dr. Duncan Stewart’s team has identified a novel stem cell with a remarkable ability to regenerate and repair the tiny blood vessels in the lungs.

Research reveals novel mechanism controlling muscle stem cells
October 5, 2022 - New research from Dr. Michael Rudnicki’s team shows for the first time that a cellular structure called a primary cilium, which functions somewhat like an antenna, plays a crucial role in priming muscle stem cells for repair and regeneration.

Lab-grown “mini-kidneys” unlock secrets of a rare disease
July 21, 2022 - Researchers have solved a medical mystery in a poorly understood disease by uncovering which cells cause tumours in patients with tuberous sclerosis complex (TSC).