HIV kept at bay with single injection every 8 weeks

August 17, 2017

Over the last two decades, HIV has been transformed from a death sentence into a chronic, treatable disease, requiring just a single pill a day to keep the virus at bay for most people. A study co-authored by Dr. Jonathan Angel has now paved the way for another treatment option: a single injection every eight weeks. Published in The Lancet, the study showed that injection of long-lasting forms of cabotegravir and rilpivirine every four or eight weeks could suppress viral replication just as well as a daily pill. The trial involved nearly 300 patients across 50 sites in five countries. Many patients at The Ottawa Hospital contributed to and benefited from this research, and many more could benefit if the drug is approved.

Authors: Margolis DA, Gonzalez-Garcia J, Stellbrink HJ, Eron JJ, Yazdanpanah Y, Podzamczer D, Lutz T, Angel JB, Richmond GJ, Clotet B, Gutierrez F, Sloan L, Clair MS, Murray M, Ford SL, Mrus J, Patel P, Crauwels H, Griffith SK, Sutton KC, Dorey D, Smith KY, Williams PE, Spreen WR.

Funding: This study was funded by ViiV Healthcare and Janssen R&D. Community support for The Ottawa Hospital is also crucial for all our research studies. Support our research into HIV and gay men’s health

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