Daniel McIsaac
MD, MPH, FRCPC
Scientist, Acute Care Research
Ottawa Hospital Research Institute
Professor & Vice Chair (Research and Innovation)
Department of Anesthesiology & Pain Medicine, University of Ottawa
Tier 1 Chair in Innovative Perioperative Care
University of Ottawa
Scientist
ICES
Anesthesiologist
The Ottawa Hospital
Research Groups
Aging Innovation in Perioperative Medicine and Surgery (AIMS)
Bio
Dan McIsaac is an anesthesiologist and CIHR-funded scientist whose research focuses on improving outcomes for people undergoing surgery. His work integrates clinical trials, knowledge synthesis, patient engagement, and data science to design and evaluate interventions that enhance perioperative care and recovery.
Dr. McIsaac's research programs focus on optimizing prehabilitation and proactive rehabilitation, improving surgical care for older adults living with frailty, evaluating health system performance, and advancing the use of patient-reported outcomes in clinical care and policy. Working closely with patients, clinicians, and health system partners, Dr. McIsaac’s research aims to generate evidence that improves recovery after surgery and supports learning health systems.
Research Goals and Interests
News
Publications
Standards for reporting research methods, interventions, and Outcomes in Surgical Prehabilitation studies (SOS-Prehab)
2026-03-04 Go to publicationEvaluation of point-of-care haemoglobin measurement accuracy in surgery (PREMISE) and implications for transfusion practice: a prospective cohort study
2025-02-01 Go to publicationRelative efficacy of prehabilitation interventions and their components: systematic review with network and component network meta-analyses of randomised controlled trials
2025-01-22 Go to publicationRelated Research at The Ottawa Hospital
- Acute Care Research Program
- Aging
- Health in older peoples
- Population health
- Pain
- Frailty
- Cohort studies
- Epidemiology
- Health services research
- Public health
- Quality Improvement
- Risk assessment
- Biostatistics
- Surgery
- Systematic reviews
- Anesthesiology
- Peri-operative medicine
- Big data
- Clinical research
- Digital and mobile health
- Patient engagement
- Artificial intelligence and data science
- Clinical trials


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CAS President Susan O'Leary presents Karim Abdulla with a certificate recognizing his victory in the CAS Resident Research Competition
Left to right G Hamilton (Systematic review of the impact of postoperative delirium on mortality); K Abdulla (Association of delayed emergency surgery with mortality); E Cole (Scoping Review of regional anesthesia in enhanced recovery protocols); S Ben Zeev (Impact of PVB on short terms outcomes after breast cancer surgery).