Jodi Warman Chardon profile picture

Contact Information

Jodi Warman Chardon, MD, MSc, FRCPC (Neurology)
613-798-5555 ext. 16221

Administrative Assistant
Sabrynna Provost
613-798-5555 ext. 16221

Jodi Warman Chardon

Associate Scientist, Neuroscience Program
Ottawa Hospital Research Institute
Associate Scientist, Clinical Epidemiology
Ottawa Hospital Research Institute
Clinician Scientist, Neurology
The Ottawa Hospital
Associate Professor, Faculty of Medicine
University of Ottawa
Co-Director, Centre for Neuromuscular Disease, Faculty of Medicine
University of Ottawa

Research Interests

Dr. Warman (Chardon)'s primary research interest focuses on identifying the molecular basis and the clinical characterization of rare myopathies, utilizing next generation sequencing (NGS), including whole exome sequencing and the clinical application of targeted large scale gene panels. Dr. Warman is utilizing next generation sequencing to drive gene identification and the phenotypic expansion of many rare neuromuscular disorders.  She and her colleagues have successfully identified several novel genes, including a novel limb girdle muscular dystrophy (LIMS2) and are continuing to assess exome, clinome and RNA sequencing as clinical tools to help patients living with neuromuscular disease.

Brief Biography

Dr Jodi Warman-Chardon is a Clinician-Scientist in the Department of Medicine at the Ottawa Hospital, Ottawa Hospital Research Institute (OHRI) in Neurosciences and Clinical Epidemiology and Department of Genetics at the Children’s Hospital of Eastern Ontario/CHEO RI. She is a Tier 2 Clinical Research Chair in Diagnosis and Discovery Pipeline for Patients with Genetic Neuromuscular Disease at the University of Ottawa. Dr. Warman received her MD/Neurology residency at the University of Ottawa and MSc from Queen’s University. She completed research and clinical fellowships in neuromuscular disorders from McGill University and neurogenetics at the University of Ottawa and is certified by the Canadian Society of Clinical Neurophysiologists (EMG). She led the strategic development and is now Director of the Ottawa Hospital Neuromuscular Centre, a diagnostic clinical research centre for patients with NMD. She is also co-director of the uOttawa Centre for Neuromuscular Disease, which unites over 60 clinical and basic NMD researchers. Dr. Warman-Chardon's research program and clinical practice focuses on the diagnosis and the clinical characterization of patients with rare or novel inherited neuromuscular disease by Magnetic Resonance Imaging (MRI) and next generation sequencing by genome and RNA sequencing.

Selected Publications

Warman-Chardon, J, Diaz-Manera, J, Tasca, Giorgio, Straub, Volker. 247th ENMC International Workshop: Muscle magnetic resonance imaging - Implementing muscle MRI as a diagnostic tool for rare genetic myopathy cohorts. Hoofddorp, The Netherlands, September 2019. Elsevier Neurom Dis. Aug 2020.

Thompson, R, Spendiff S, Roos A, Bourque PR, Warman-Chardon, J, Kirschner J, Horvath R, Lochmuller, H. Diagnosing inherited neuromuscular diseases through omics and other approaches: the old ways and the new. Lancet Neurol. 2020, June; 19, 522-32

Warman Chardon J, Díaz-Manera J, Tasca G, Bönnemann CG, Gómez-Andrés D, Heerschap A, Mercuri E, Muntoni F, Pichiecchio A, Ricci E, Walter MC, Hanna M, Jungbluth H, Morrow JM, Fernández-Torrón R, Udd B, Vissing J, Yousry T, Quijano-Roy S, Straub V, Carlier RY; MYO-MRI Working Group. MYO-MRI diagnostic protocols in genetic myopathies. Neuromuscul Disord. 2019 Nov;29(11):827-841.

David Pellerin, Asli Aykanat, Benjamin Ellezam, Emily C Troiano, Jason Karamchandani, Marie-Josée Dicaire, Marc Petitclerc, Rebecca Robertson, Xavier Allard-Chamard, Denis Brunet, Chamindra G Konersman, Jean Mathieu, Jodi Warman Chardon, Vandana A Gupta, Alan H Beggs, Bernard Brais, Nicolas Chrestian. Novel Recessive TNNT1 Congenital Core-Rod Myopathy in French Canadians. Ann Neurol Apr 2020

Kernohan KD, Frésard L, Zappala Z, Hartley T, Smith KS, Wagner J, Xu H, McBride A, Bourque PR, Consortium CRC, Bennett SAL, Dyment DA, Boycott KM, Montgomery SB, Warman Chardon J. Whole-transcriptome sequencing in blood provides a diagnosis of spinal muscular atrophy with progressive myoclonic epilepsy. Hum Mutat. 2017 Jun;38(6):611-614

Diseases, conditions and populations of interest

Research and clinical approaches