Our group is interested in developing best practice recommendations for optimal treatment of emergency department patients with skin and soft tissue infections. We aim to develop the highest quality of evidence to inform best practices by conducting randomized controlled trials to identify the best treatment options,  including optimal antibiotic doses, agents and adjunctive therapies. 

Yadav K, Ohle R, Yan JW, Eagles D, Perry JJ, Zvonar R, Keller M, Nott C, Corrales-Medina V, Shoots L, Tran E, Suh KN, Lam PW, Fagan L, Song N, Dobson E, Hawken D, Taljaard M, Sikora L, Brehaut J, Stiell IG, Graham ID; Network of Canadian Emergency Researchers. Canadian Emergency Department Best Practices Checklist for Skin and Soft Tissue Infections Part 1: Cellulitis. CJEM. 2024 Sep;26(9):593-599. doi: 10.1007/s43678-024-00754-9. Epub 2024 Aug 5. PMID: 39102151.81. 

Yadav K, Ohle R, Yan JW, Eagles D, Perry JJ, Zvonar R, Keller M, Nott C, Corrales-Medina V, Shoots L, Tran E, Suh KN, Lam PW, Fagan L, Song N, Dobson E, Hawken D, Taljaard M, Sikora L, Brehaut J, Stiell IG, Graham ID; Network of Canadian Emergency Researchers. Canadian emergency department best practices checklist for skin and soft tissue infections part 2: skin abscess. CJEM. 2024 Sep;26(9):600-606. doi: 10.1007/s43678-024-00739-8. Epub 2024 Jul 12. PMID: 38995607.80. 

Yadav K, Ohle R, Yan JW, Eagles D, Perry JJ, Zvonar R, Keller M, Nott C, Corrales-Medina V, Shoots L, Tran E, Suh KN, Lam PW, Fagan L, Song N, Dobson E, Hawken D, Taljaard M, Sikora L, Brehaut J, Stiell IG, Graham ID; Network of Canadian Emergency Researchers. Canadian Emergency Department Best Practices Checklist for Skin and Soft Tissue Infections Part 3: Necrotizing Fasciitis. CJEM. 2024 Sep;26(9):607-611. doi:10.1007/s43678-024-00737-w. Epub 2024 Jul 12. PMID: 38995608.

Yadav K, Eagles D, Perry JJ, Taljaard M, Sandino-Gold G, Nemnom MJ, Corrales-Medina V, Suh KN, Stiell IG. High-dose cephalexin for cellulitis: a pilot randomized controlled trial. CJEM. 2023 Jan 2. Epub ahead of print. doi: 10.1007/s43678-022-00433-7. PMID: 36592299.

Hamill L, Keijzers G, Robertson S, Ventre C, Song N, Glasziou P, Scott AM, Clark J, Yadav K. Anti-inflammatories as adjunct treatment for cellulitis: a systematic review and meta-analysis. CJEM. 2024 Jul;26(7):472-481. doi: 10.1007/s43678-024-00718-z. Epub 2024 May 26. PMID: 38796807.