What We Do
- Determine how risk factors contribute to ovarian cancer initiation and progression
- High-throughput genomics to investigate models of ovarian cancer
- Design, develop, and test novel immune therapies for ovarian cancer
- Evaluate chromatin remodelling proteins involved in regulating cell state
For information regarding individual projects, please see the Lab Members section
Selected Publications
Hodgkinson K, LA Forrest, N Vuong, K Garson, B Djordjevic, and BC Vanderhyden. (2018). GREB1 is a novel estrogen receptor-regulated tumour promoter that is frequently expressed in ovarian cancer. Oncogene Jul 4. doi: 10.1038/s41388-018-0377-y. [Epub ahead of print]
Rodriguez GM, Galpin KJC, McCloskey CW and Vanderhyden BC (2018). The tumor microenvironment of epithelial ovarian cancer and its influence on response to immunotherapy. Cancers (Basel). 10(8). pii: E242. doi: 10.3390/cancers10080242.
McCloskey CW, Rodriguez GM, Galpin KJC and Vanderhyden BC (2018). Ovarian cancer immunotherapy: Preclinical models and emerging therapeutics. Cancers (Basel). 10(8). pii: E244. doi: 10.3390/cancers10080244.
Vuong NH, O Salah Salah, and BC Vanderhyden (2017). 17β-Estradiol sensitizes ovarian surface epithelium to transformation by suppressing Dab2 expression. Scientific Reports 7: 16,702.
Alwosaibai K, A Abedini, EM Al-Hujaily, Y Tang, K Garson, O Collins and BC Vanderhyden (2017). PAX2 maintains the differentiation of oviductal epithelium and inhibits the transition to a stem cell-like state. Oncotarget 8: 76,881-76,897.
Meet the Vanderhyden Lab
