Ottawa Hospital Research Institute

Research News

	New scientist profile: Space science to better treat rehabilitation patients April 30, 2025 - Space anemia, the lowered red blood cell counts in astronauts during and after space travel, has puzzled researchers for decades. But thanks to Dr. Guy Trudel’s work with astronauts on MARROW, we now have a much better understanding of space anemia a
	Big blood savings: large trial in JAMA shows taking less blood for lab testing reduces transfusions in intensive care October 12, 2023 - A world-first clinical trial published in JAMA could provide an easy way to save tens of thousands of units of blood every year in Canada and much more worldwide. The trial, which involved more than 27,000 patients in 25 adult intensive care units (I
	Space travel depletes red blood cells and bone, but bone marrow fat may come to the rescue August 21, 2023 - A study of 14 astronauts suggests that while space travel depletes red blood cells and bone, the body can eventually replenish them back on Earth with the help of fat stored in the bone marrow.
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	Being in space destroys more red blood cells January 14, 2022 - A world-first study has revealed how space travel can cause lower red blood cell counts, known as space anemia. Analysis of 14 astronauts showed their bodies destroyed 54 percent more red blood cells in space than they normally would on Earth, accord

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Berardi, Philip MD, PhD, FRCPC	Clinician Investigator (CR)	Aging, Anemia, Bleeding disorders, Blood cancer, Cancer, COVID-19, Health equity, Health in older peoples, Sickle cell anemia, Thalassemia, Thrombosis / thromboembolism	Artificial intelligence and data science, Basic research, Bioinformatics, Biomarkers, Cancer biotherapeutics, Cell therapy, Epigenetics, Gene expression, Genetics, Genomics, Immunotherapy, Molecular and cellular biology, Stem cells, Translational research
Martel, Guillaume MD, MSc (Epi), FRCSC, FACS	Senior Scientist (ACR)	Anemia, Bleeding disorders, Colorectal cancer, Liver cancer, Liver disease, Pancreatic cancer	Anesthesiology, Clinical research, Clinical trials, Peri-operative medicine, Surgery, Systematic reviews, Transfusions
Trudel, Guy MD	Senior Scientist (ICD)	Anemia, Bone and joint degeneration, Musculoskeletal conditions	Basic research, Biomarkers, Molecular and cellular biology, Regenerative medicine, Rehabilitation

Related Resources

The Ottawa Hospital Hematology and Thrombosis Clinic

Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "Anemia” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

Publications

The following research publications are pulled from PubMed using the search terms "Anemia" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Maintenance olaparib monotherapy in patients with platinum-sensitive relapsed ovarian cancer without a germline BRCA1 and/or BRCA2 mutation: Final overall survival results from the OPINION trial.
2025-04-28

Association between anticoagulant-related bleeding and mortality in patients with hematological malignancies and cancer-associated venous thromboembolism.
2025-04-01

Brentuximab Vedotin Combination for Relapsed Diffuse Large B-Cell Lymphoma.
2025-03-20

Daratumumab for Posttransplant Autoimmune Hemolytic Anemia.
2025-03-17

Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage.
2025-03-13

Restrictive versus Liberal Transfusion in Myocardial Infarction - A Patient-Level Meta-Analysis.
2025-02-01

An emergency medicine review: Multiple myeloma and its complications.
2025-02-01

Effect of Four Hemoglobin Transfusion Threshold Strategies in Patients With Acute Myocardial Infarction and Anemia : A Target Trial Emulation Using MINT Trial Data.
2024-11-01

Restrictive or Liberal Transfusion Strategy in Patients With Acute Myocardial Infarction and Anemia: 6-Month Mortality in the MINT Trial.
2024-09-24

Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury.
2024-08-22

View more on PubMed