Ottawa Hospital Research Institute

Research News

	How to use audit and feedback to improve patient care June 20, 2025 - Audit and feedback is one of the most effective ways to support practice change in health care and improve patient care, but it doesn’t always work perfectly. To understand how audit and feedback is most likely to succeed, an international team of re
	Ottawa researchers continue to set international standards for reporting clinical trials May 23, 2025 - Nearly 30 years ago, the CONSORT statement transformed clinical trials around the world
	New scientist profile: Dr. Stuart Nicholls aims to improve patient engagement in clinical trials and health research April 11, 2025 - Clinical trials can offer new treatment options and improve health care, but many patients face barriers and burdens to participating.
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	TOH researchers continue to play key role in developing research reporting guidelines February 18, 2025 - Several researchers at The Ottawa Hospital contributed to the new CONSORT statement for cluster randomized crossover trials, including Drs. Jeremy Grimshaw, David Moher and Monica Taljaard.
	Canada isn’t registering and reporting results of all clinical trials. Here’s how to fix that. January 4, 2024 - Registering clinical trials helps increase research transparency and reduce redundancy. Most Canadian clinical trials are not meeting World Health Organization guidelines on registration and reporting of results, according to an analysis published in
	Meet Dr. Manoj Lalu, the clinician-scientist bringing lab discoveries to patients every day March 16, 2023 - From looking at how we can use stem cells to treat diseases like sepsis to dealing with patients directly in the ICU and OR, Dr. Lalu is making an impact behind the scenes and beyond.
	Scientists call for "living evidence reviews" to combat COVID confusion December 15, 2021 - Policy missteps will continue to overshadow the global response to Covid because policymakers are overwhelmed with rapidly shifting research evidence, according to scientists writing in the peer-reviewed journal Nature.
	Researchers update PRISMA guideline to improve health research March 29, 2021 - Dr. David Moher and colleagues have published an updated PRISMA 2020 statement and explanation and elaboration to ensure these important guidelines continue to help researchers produce high-quality systematic reviews.
	Partnering with the marginalized December 11, 2020 - To tackle health-care inequities affecting vulnerable populations, Smita Pakhalé turns to community peer researchers in a grassroots approach to epidemiological research.
	Dr. David Moher elected a Fellow of the Royal Society of Canada September 16, 2020 - One of the world’s most cited researchers, Dr. Moher is considered a pioneer in the science of conducting and reporting systematic reviews, and has dedicated his career to supporting the global academic community in reporting clinical research.
	5 ways to enhance research integrity and avoid the risks of ‘publish or perish’ in academia July 16, 2020 - Amid growing criticism of the traditional “publish or perish” system for rewarding academic research, an international team has developed five principles that institutions can follow to measure and reward research integrity. The team believes that ap
	Helping evidence-based public health guidelines work in the real world April 3, 2019 - Dr. Jeremy Grimshaw played an important role in an international exercise to strengthen how the World Health Organization develops guidelines to improve public health.
	Trio of BMJ papers to impact how clinical research is performed January 9, 2019 - Researchers at The Ottawa Hospital and the University of Ottawa played important roles in three papers recently published in The BMJ (British Medical Journal) that are expected to impact how clinical research is conducted around the world. The first
	Researchers push for better patient engagement June 27, 2018 - Research improves patient care, and a growing movement aims to engage and involve patients in the research process from start to finish. However, little is known about what meaningful patient engagement in research looks like. To find out, Dr. Dean F
	Finding better ways to bring health research to life: World-leading Centre for Implementation Research opens at The Ottawa Hospital January 18, 2018 - Researchers regularly make discoveries that have the potential to improve patient care and quality of life. However, getting those findings adopted by health-care systems can be a challenge. Researchers at The Ottawa Hospital are already world l

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Chen, Innie MD, MPH, FRCSC	Scientist (Acute Care Research)	Health equity, Population health, Pregnancy, Women's health	Clinical research, Epidemiology, Health research methods, Patient engagement, Quality Improvement, Systematic reviews
Clemons, Mark MB BS, BMedSci, MSc, MD, FRCP, FRCPC	Scientist (Cancer Research)	Breast cancer, Cancer	Basic research, Clinical research, Clinical trials, Health research methods, Knowledge translation and implementation research
Delluc, Aurelien MD, Ph. D.	Scientist (Inflammation and Chronic Disease)	Thrombosis / thromboembolism	Clinical research, Clinical trials, Health research methods
El-Chaar, Darine MD, FRCSC, Msc	Scientist (Inflammation and Chronic Disease)	Autoimmune disease, COVID-19, Diabetes, Infectious disease, Inflammatory bowel syndrome, Maternal and fetal health, Newborn and child health, Population health, Pregnancy, Women's health	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health research methods, Health services research, Public health, Qualitative methods, Quality Improvement, Systematic reviews
Fergusson, Dean PhD, MHA, FCAHS	Program Director and Senior Scientist (Methodological and Implementation Research)	Cancer, COVID-19, Kidney disease, Septic shock, Vascular, heart and metabolic disease	Clinical trials, Health services research, Health technology, Patient engagement, Pragmatic trials, Surveys, Translational research, Biostatistics, Clinical research, Cluster randomized trials, Cohort studies, Critical care, Health research methods, Qualitative methods, Quality Improvement, Systematic reviews, Transfusions
Graham, Ian MA, PhD, FCAHS, NYAM, FRSC	Senior Scientist (Methodological and Implementation Research)		Health professional behaviour change, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Shared decision making
Grimshaw, Jeremy MBCHB, PHD	Senior Scientist Emeritus (Methodological and Implementation Research)	COVID-19	Behaviour, Cluster randomized trials, Health professional behaviour change, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Qualitative methods, Quality Improvement, Surveys, Systematic reviews
Hatcher, Simon BSc MBBS MMedSc MD FRCPC FRANZCP MRCPsych	Scientist (Neuroscience)	Anxiety, Brain and neuromuscular disease, COVID-19, First Nations, Inuit and Métis Health, Health equity, Mental health, Traumatic brain injury, Depression, Health in disadvantaged peoples, Suicide	Clinical research, Digital and mobile health, Health economics, Health professional behaviour change, Health research methods, Health services research, Health technology, Knowledge translation and implementation research, Patient engagement, Prevention, Public health, Qualitative methods, Clinical trials, Cluster randomized trials, Epidemiology, Psychology, Systematic reviews
Hawken, Steven PhD	Senior Scientist (Methodological and Implementation Research)	Population health, Global health, Newborn and child health, Pregnancy	Artificial intelligence and data science, Big data, Biomarkers, Health services research, Immunization, Biostatistics, Epidemiology, Health research methods
Hutton, Brian MSc, PhD	Senior Scientist (Methodological and Implementation Research)	Addiction, Anxiety, Breast cancer, Depression, Health equity, Health in disadvantaged peoples, Maternal and fetal health, Mental health, Population health, Suicide, Cancer	Clinical research, Cohort studies, Epidemiology, Health research methods, Health services research, Patient safety, Public health, Rapid reviews, Biostatistics, Clinical trials, Systematic reviews
Kendzerska, Tetyana MD, PhD	Associate Scientist (Inflammation and Chronic Disease)	Aging, Chronic obstructive pulmonary disease, Heart disease, Lung disease, Population health, Women's health	Biostatistics, Clinical research, Cohort studies, Epidemiology, Health research methods, Health services research, Systematic reviews
Lalu, Manoj MD, PhD, FRCPC	Scientist (Acute Care Research)	Blood cancer, COVID-19, Heart disease, Stroke, Vascular, heart and metabolic disease	Anesthesiology, Basic research, Cell therapy, Clinical research, Clinical trials, Disease models, Health research methods, Model organisms, Patient engagement, Regenerative medicine, Stem cells, Translational research
Lemaire, Edward PhD	Affiliate Investigator (Methodological and Implementation Research)	Aging, Bone and joint degeneration, Bone and joint injuries, Concussion, Global health, Musculoskeletal conditions, Spinal cord injury, Traumatic brain injury, Traumatic injuries	Big data, Clinical research, Clinical trials, Health research methods, Quality Improvement, Rehabilitation, Health technology
Manuel, Douglas MD, MSc, FRCPC	Senior Scientist (Methodological and Implementation Research)	Aging, Alzheimer's, Cancer, COVID-19, Dementia, Diabetes, Frailty, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, Immigrant and refugee health, Infectious disease, Obesity, Parkinson's, Population health, Stroke, Vascular cognitive impairment, Vascular, heart and metabolic disease	Artificial intelligence and data science, Big data, Bioinformatics, Biostatistics, Digital and mobile health, Epidemiology, Health research methods, Health services research, Prevention, Public health
McInnes, Matthew MD PhD FRCPC	Scientist (Methodological and Implementation Research)	Cancer, Liver cancer	Clinical research, Epidemiology, Health research methods, Imaging, Journalology, Systematic reviews
Moher, David PhD	Senior Scientist (Methodological and Implementation Research)		Epidemiology, Health research methods, Health services research, Journalology, Knowledge translation and implementation research, Patient engagement, Systematic reviews
Nicholls, Stuart BSc(Hons), MSc, MRes, PhD	Scientist (Methodological and Implementation Research)	Health equity	Health research methods, Health services research, Health technology, Knowledge translation and implementation research, Patient decision aids, Patient engagement, Pragmatic trials, Qualitative methods, Quality Improvement, Rapid reviews, Systematic reviews
Ramsay, Timothy PhD	Senior Scientist (Methodological and Implementation Research)	Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury	Artificial intelligence and data science, Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Santos, Marlise MD (FRCPC), MSc, MPH	Clinician Investigator (Neuroscience)	Alzheimer's, Anxiety, Ataxia, Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Brain and neuromuscular disease, Brain cancer, Cancer, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Sickle cell anemia, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease	Artificial intelligence and data science, Basic research, Behaviour, Biostatistics, Cancer biotherapeutics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews
Solmi, Marco MD, PhD, Psychiatrist	Clinician Investigator (Neuroscience)	Addiction, Anxiety, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Dementia, Depression, Mental health, Schizophrenia, Suicide	Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health research methods, Neuro-stimulation, Pharmacology, Pragmatic trials, Surveys, Systematic reviews
Sood, Manish MD, FRCPC, MSc	Senior Scientist (Inflammation and Chronic Disease)	Bleeding disorders, Heart disease, Hypertension, Population health, Thrombosis / thromboembolism	Big data, Cohort studies, Epidemiology, Health research methods, Health services research, Pharmacology, Prevention
Stacey, Dawn RN, PhD, FRSC, FCAHS, FAAN, FCAN, CON(C)	Senior Scientist (Methodological and Implementation Research)		Clinical research, Clinical trials, Health professional behaviour change, Health research methods, Health services research, Knowledge translation and implementation research, Patient decision aids, Patient engagement, Qualitative methods, Quality Improvement, Shared decision making, Surveys, Systematic reviews
Taljaard, Monica PhD	Senior Scientist (Methodological and Implementation Research)		Biostatistics, Clinical decision rules, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health professional behaviour change, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Quality Improvement
Thavorn, Kednapa BPharm, MPharm, PhD	Senior Scientist (Methodological and Implementation Research)	Cancer, COVID-19, Diabetes, Gastrointestinal disease, Glaucoma, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, HIV, Immigrant and refugee health, Population health, Septic shock, Stroke, Thrombosis / thromboembolism, Vision	Clinical research, Cohort studies, Epidemiology, Health economics, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Pharmacy, Public health, Quality Improvement, Systematic reviews
Tran, Alexandre MD, MSc, FRCSC	Associate Scientist (Acute Care Research)	Traumatic injuries	Clinical decision rules, Clinical research, Clinical trials, Critical care, Health research methods, Surgery, Systematic reviews
Van Walraven, Carl MD, FRCPC	Senior Scientist (Methodological and Implementation Research)		Big data, Biostatistics, Epidemiology, Health research methods, Health services research
Walker, Mark MD, FRCPC, MSc, MScHCM	Senior Scientist (Acute Care Research)	Global health, Health equity, Infertility, Maternal and fetal health, Newborn and child health, Population health, Pregnancy, Women's health	Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health economics, Health promotion, Health research methods, Health services research, Knowledge translation and implementation research, Pragmatic trials, Prevention, Public health, Quality Improvement, Rapid reviews, Risk assessment, Surveys, Systematic reviews

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