Model organisms

Research News


Vascular development may be at risk in autism Vascular development may be at risk in autism
July 13, 2020 - A Canadian collaboration led by Dr. Baptiste Lacoste has undertaken the first ever in-depth study of vasculature in the autistic brain. The product of four years of work, a paper published today in Nature Neuroscience lays out several lines of novel
New mouse model to reveal insights into mild spinal muscular atrophy New mouse model to reveal insights into mild spinal muscular atrophy
June 4, 2020 - Dr. Marc-Olivier Deguise from Dr. Rashmi Kothary’s team has developed a new mouse model of mild spinal muscular atrophy (SMA). Until now, researchers only had good animal models of the most severe forms of this disease.
Chance discovery linking diet to type 1 diabetes started whole new field of research Chance discovery linking diet to type 1 diabetes started whole new field of research
October 22, 2018 - In the early 1980's, Dr. Fraser Scott was conducting nutritional studies on rats that were supposed to develop type 1 diabetes—except they didn't. He discovered that changing the diet of these diabetes-prone rodents had prevented the disease. Making
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Addison, Christina
PhD
Senior Scientist
(CR)
Bone and joint degeneration, Cancer, Lung cancer, Lung disease, Pancreatic cancer, Prostate cancer, Breast cancer Basic research, Clinical research, Cohort studies, Disease models, Drug development, Genetics, Imaging, Model organisms, Translational research, Molecular and cellular biology
Ardolino, Michele
PhD
Senior Scientist
(CR)
Blood cancer, Brain cancer, Breast cancer, Cancer, Colorectal cancer, Head and neck cancer, Liver cancer, Lung cancer, Ovarian cancer, Pancreatic cancer, Prostate cancer, Skin cancer, Soft tissue sarcoma Basic research, Cancer immunotherapy, Cell therapy, Clinical research, Disease models, Immunization, Immunotherapy, Model organisms, Molecular and cellular biology, Transgenic/knockout models, Translational research
Brand, Marjorie
PhD
Senior Scientist Affiliate
(RM)
Blood cancer, Sickle cell anemia, Thalassemia, Vascular, heart and metabolic disease Artificial intelligence and data science, Basic research, Bioinformatics, Disease models, Epigenetics, Gene expression, Genomics, Imaging, Model organisms, Molecular and cellular biology, Proteomics, Stem cells, Systems biology, Transgenic/knockout models
Burger, Dylan
PhD
Senior Scientist
(ICD)
Aging, Diabetes, Heart disease, Hypertension, Kidney disease, Maternal and fetal health, Obesity, Thrombosis / thromboembolism, Type 1 diabetes, Vascular cognitive impairment, Vascular, heart and metabolic disease Basic research, Biomarkers, Disease models, Exercise, Extracellular vesicles / exosomes, Imaging, Model organisms, Molecular and cellular biology, Pharmacology, Proteomics, Regenerative medicine, Stem cells, Transgenic/knockout models, Translational research
Colavita, Antonio
PhD
Senior Scientist
(NS)
Spinal cord injury Genetics, Model organisms, Molecular and cellular biology
Gage, Blair
PhD
Scientist
(RM)
Bleeding disorders, Diabetes, Liver cancer, Liver disease, Vascular, heart and metabolic disease Basic research, Bioinformatics, Cell therapy, Disease models, Gene expression, Gene therapy, Genetics, Genomics, Model organisms, Molecular and cellular biology, Regenerative medicine, Stem cells, Translational research, Transplantation
Gray, Douglas
PhD
Senior Scientist Emeritus
(CR)
Aging, Cancer, Lung cancer, Parkinson's Basic research, Disease models, Genomics, Imaging, Transgenic/knockout models, Genetics, Model organisms, Molecular and cellular biology
Kothary, Rashmi
Ph.D.
Senior Scientist
(RM)
Neuromuscular disease, Amyotrophic lateral sclerosis, Dystonia, Multiple sclerosis, Muscular dystrophy, Spinal muscular atrophy Basic research, Disease models, Drug development, Epigenetics, Epigenetics, Gene therapy, Genetics, Imaging, Lipidomics, Model organisms, Molecular and cellular biology, Proteomics, Regenerative medicine, Transgenic/knockout models, Translational research
Lacoste, Baptiste
PhD
Senior Scientist
(NS)
Stroke, Vascular cognitive impairment, Autism Basic research, Disease models, Gene expression, Genomics, Stem cells, Genetics, Imaging, Model organisms, Molecular and cellular biology, Transgenic/knockout models
Lalu, Manoj
MD, PhD, FRCPC
Scientist
(ACR)
Blood cancer, COVID-19, Heart disease, Stroke, Vascular, heart and metabolic disease Anesthesiology, Basic research, Cell therapy, Clinical research, Clinical trials, Disease models, Health research methods, Model organisms, Patient engagement, Regenerative medicine, Stem cells, Translational research
Mattar, Pierre
PhD
Senior Scientist
(RM)
Autism, Autoimmune diseases of the nervous system, Glaucoma, Intellectual disabilities, Macular degeneration, Retinal disease, Vision Basic research, Bioinformatics, Cell therapy, Epigenetics, Gene expression, Genetics, Genomics, Model organisms, Molecular and cellular biology, Proteomics, Regenerative medicine, Stem cells, Systems biology, Transgenic/knockout models
Ngsee, John
Ph.D.
Affiliate Investigator
(NS)
Amyotrophic lateral sclerosis, Dementia, Parkinson's Cell therapy, Drug development, Model organisms, Molecular and cellular biology
Rudnicki, Michael
OC, PhD, FRS, FRSC
Program Director and
Senior Scientist
(RM)
Muscular dystrophy, Neuromuscular disease Basic research, Bioinformatics, Disease models, Epigenetics, Genetics, Genomics, Model organisms, Molecular and cellular biology, Proteomics, Regenerative medicine, Stem cells, Transgenic/knockout models
Vanderhyden, Barbara
PhD
Senior Scientist
(CR)
Cancer, Infertility, Ovarian cancer, Women's health Basic research, Bioinformatics, Biomarkers, Cancer biotherapeutics, Disease models, Drug development, Epigenetics, Gene expression, Genomics, Immunotherapy, Model organisms, Molecular and cellular biology, Oncolytic viruses, Stem cells, Transgenic/knockout models, Translational research, Viral therapy