Study to explore if protein protects against inflammation found in obesity and Type 2 Disabetes
October 8, 2014
Dr. Hsiao-Huei Chen has received a grant from Canadian Diabetes Association valued at $280,000 over three years for the project “Neural and immune control of metabolism” Dr. Chen plans to use the grant money to study obesity as a risk factor for developing type 2 diabetes, and chronic inflammation, which is seen in both obesity and type 2 diabetes. Normally, inflammation is the body's healthy response to infection or injury, such as when a cut becomes hot, red, and swollen. However, obesity can cause chronic inflammation in the whole body, which can cause health problems, like type 2 diabetes. Dr. Chen has found that when the diet includes a lot of saturated fat, a certain protein's levels become low, which may be a cause of the whole-body inflammation that leads to obesity and pre-diabetes, and eventually to type 2 diabetes. Dr. Chen's team has found that this protein acts differently in male and female mice. Dr. Chen is studying how and why this happens in order to find out if whole-body inflammation can be stopped.
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