Carolina Ilkow profile picture

Contact Information

Carolina Ilkow, PhD
613-737-8899 ext 75208
cilkow@ohri.ca

E-mail: cilkow@ohri.ca and cilkow@uottawa.ca

What We Do

Selected Publications

Selected Publications:

1- Ilkow CS, M. Marguerie, C. Batenchuk, J. Mayer, D. Ben Neriah, S. Cousineau, T. Falls, V. Jennings, M. Boileau, D. Bellamy, D. Bastin, C. Tanese de Souza, A. Alkayyal, J. Zhang, F. Le Boeuf, R. Arulanandam, P. Sampath, S. Thorne, P. Paramanthan, A. Chatterjee, R.M. Strieter, M. Burdick, C. Addison, D. Stojdl, H. Atkins, R. Auer, J-S Diallo, B. Lichty, and J.C. Bell. “Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity”. Nature Medicine. 2015 May;21(5):530-6.

2- R. Arulanandam, C. Batenchuk, F. A. Angarita, K. Ottolino-Perry, S. Cousineau, A. Mottashed, E. Burgess, T. Falls, N. De Silva, J. Tsang, G. Howe, M-C Bourgeois-Daigneault, D. Conrad, M. Daneshmand, C. Breitbach, D. Kirn, L. Raptis, S. Sad, H. Atkins, M. Huh, J-S Diallo, B. Lichty, C.S. Ilkow, F. Le Boeuf, C. Addison, J. McCart and John C. Bell. “PRD1-BF1 drives VEGF-mediated innate immune suppression in tumor vasculature”. Cancer Cell. 2015 Aug 10;28(2):210-224.

3- Beug ST, Tang VA, LaCasse EC, Cheung HH, Beauregard CE, Brun J, Nuyens JP, Earl N, St-Jean M, Holbrook J, Dastidar H, Mahoney DJ, Ilkow C, Le Boeuf F, Bell JC, Korneluk RG (2014). “Smac mimetics and innate immune stimuli synergize to promote tumor death”. Nature Biotechnology. 2014 Feb;32(2):182-90.

4- Ilkow CS, Swift SL, Bell JC, Diallo JS (2014). “From scourge to cure: tumour-selective viral pathogenesis as a new strategy against cancer”. PLoS Pathogens. 2014 Jan;10(1).

5- Ilkow CS, Goping, IS, and Hobman TC. (2011). “The Rubella virus capsid protein blocks apoptosis by attenuating the pore-forming ability of Bax”. PLoS Pathogens. Feb;7(2).

6- Ilkow, CS, Willow, SD, and Hobman, TC. (2010). “Rubella virus capsid protein: a small protein with big functions”. Future microbiology. 5(4):571-84.

7- *Ilkow, CS, *Weckbecker, D, Cho, WJ, Meier, S, Beatch, MD, Goping, IS, Herrmann, JM, and Hobman, TC. (2010). “The Rubella Virus capsid inhibits import of proteins into mitochondria”. Journal of Virology 84(1):119-30. (* These authors contributed equally to this work).

8- Ilkow, CS, Mancinelli, V, Beatch, MD, and Hobman, TC. (2008) “The Rubella virus capsid protein binds Poly (A) binding protein and inhibits translation”. Journal of Virology 82(9):4284-94.

9- *Law, LMJ, *Ilkow, CS, Tzeng, W-P, Rawluk, M, Stuart, DT, and Hobman, TC. (2006). “Analysis of phosphorylation events in the Rubella virus capsid protein: Roles in early replication”. Journal of Virology 80:6917-6925. (* These authors contributed equally).

Meet the Ilkow Lab

Young scientists are welcome to apply for a position as a master student, graduate student or post-doctoral fellow in the lab. A strong cancer biology and/or virology background is not required, whereas applicants should be willing to work hard in a collaborative environment.

Guidelines to apply as a Graduate Student at the University of Ottawa: https://www.uottawa.ca/graduate-studies/programs-admission/apply. Post-doctoral fellows are strongly encouraged to obtain independent funding during their first year of work in the lab.

Applications should include a resume and a short statement of research interest, clearly describing why the applicant wants to join the lab. At least two references should be sent independently to Dr. Carolina Ilkow (cilkow@uottawa.ca).