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Contact Information

Antonio Colavita, PhD
(613) 562-5800 x8631

Antonio Colavita

Senior Scientist, Neuroscience Program
Ottawa Hospital Research Institute

Research Interests

My laboratory is interested in using genetic and molecular approaches in C. elegans to study nervous system development. We are interested in gaining new insight into the establishment and maintenance of neuronal polarity, neuronal migration and axon guidance.

Brief Biography

Dr. Colavita completed a Ph.D. at the University of Toronto with Joseph Culotti studying the Netrin axon guidance pathway. He then pursued postdoctoral research at Stanford University with Marc Tessier-Lavigne to study molecular mechanisms involved in axon branching.

Selected Publications

Shah P#; Tanner M#; Kovacevic I; Rankin A; Marshall T; Noblett N; Tran N; Roenspies T; Hung J; Chen Z; Slatculescu C; Perkins TJ; Bao Z;* and Colavita A* (2017), PCP and SAX-3/Robo pathways cooperate to regulate convergent-extension-based nerve cord assembly in C. elegans. Developmental Cell; 41(2): 195-203

Carr D; Sanchez-Alvarez L; Imai JH; Slatculescu C; Noblett N; Mao L; Beese L; and Colavita A (2016), A farnesyltransferase acts to inhibit ectopic neurite formation in C. elegans. PLoS One; 11(6): e0157537

Sanchez-Alvarez L; Visanuvimol J; McEwan A; Su A; Imai JH; Colavita A (2011), VANG-1 and PRKL-1 cooperate to negatively regulate neurite formation in Caenorhabditis elegans, PLoS Genet, 7(9): e1002257

Habibi-Babadi N; Su A; de Carvalho CE; Colavita A (2010), The N-Glycanase png-1 Acts to Limit Axon Branching during Organ Formation in Caenorhabditis elegans, Journal of Neuroscience, 30(5): 1766-1776

Diseases, conditions and populations of interest

Spinal cord injury

Research and clinical approaches

Genetics; Model organisms; Molecular and cellular biology