Scientist, Acute Care Research
Ottawa Hospital Research Institute

Division Head, Department of Thoracic Surgery
The Ottawa Hospital, University of Ottawa

Professor, Faculty of Medicine
University of Ottawa

Director, Dynamical Analysis Laboratory
Ottawa Hospital Research Institute

Founder and Chief Executive Officer
Therapeutic Monitoring Systems (TMS) Inc.

Andrew JE Seely’s research is all performed by a longstanding remarkable multidisciplinary research team of coordinators, engineers, assistants, students, and more, all supported by world class co-principal investigators and collaborators. Domains of research interests include: (1) understanding the origins and significance of complex biologic vital sign variability; (2) combining multiorgan variability with predictive modelling from large clinical studies to create predictive decision support that help advise doctors regarding a patient’s risk of future deterioration due to infection, risk of extubation failure after separation from a ventilator, risk of not successfully proceeding with organ donation attempt following circulatory death, and more; (3) development and implementation of a systematic means to continuously monitor all adverse events after all thoracic surgery along with novel feedback methods to improve surgical care; and (4) multidisciplinary research exploring the clinical insights of complex systems science (e.g. emergence, uncertainty) and the importance of human entropy production to human health.

Andrew JE Seely is a thoracic surgeon and intensivist at The Ottawa Hospital, Scientist at the Ottawa Hospital Research Institute, Professor of Surgery within the Divisions of Thoracic Surgery and Critical Care Medicine at the University of Ottawa, Division Head in the Department of Thoracic Surgery at The Ottawa Hospital, and Past President of the Canadian Association of Thoracic Surgeons. Dr. Seely is the Founder and Chief Executive Officer of Therapeutic Monitoring Systems Inc. Dr. Seely’s education includes an undergraduate honors in Physics at Carleton University, followed by medical school, general surgery training, and a doctoral degree in basic science from McGill University, and thoracic surgery and critical care medicine training at the University of Ottawa. Dr. Seely’s program of research focuses on the innovative use of clinical data to monitor systems and improve patient care, focussed on reducing uncertainty and improving decision making in critically ill patients, and reducing adverse events following surgery. Dr. Seely has supervised several graduate students, built research teams, published over 230 peer-reviewed papers, presents annually at international meetings and has been awarded over $9M in competitive grant funding. He shares his family life with Kathy Patterson and their daughters Phoebe and Ruby in Ottawa.

1.    Burns KEA, Allan JE, Lee E, Santos-Taylor M, Kay P, Greco P, Every H, Mooney O, Tanios M, Tan E, Herry CL, Scales NB, Gouskos A, Tran A, Iyengar A, Maslove DM, Kutsogiannis J, Charbonney E, Mendelson A, Lellouche F, Lamontagne F, Scales D, Archambault P, Turgeon AF, Seely AJE, Group CCCT. Liberation from mechanical ventilation using Extubation Advisor Decision Support (LEADS): protocol for a multicentre pilot trial. BMJ Open. 2025 Mar 18;15(3):e093853. doi: 10.1136/bmjopen-2024-093853.  

2.    Dhanani S., Ramchandani R, Allan J, Hudek N, Herry CL, Scales N,  Adhikari, NKJ, Brehaut JC, Burns KEA, Chassé M, Iyengar AM, Meade MO, Ramsay T, Scales DC, Selzner M, Sener A, Slessarev M, Talbot H, Weiss MJ, Zaltzman J, Seely AJE. Feasibility and Optimization of Donation Advisor: a Decision Support Tool for Deceased Organ Donation and Transplantation. Transplantation Direct. 2025 March; 11(3): e1748, doi: 10.1097/TXD.0000000000001748.  

3.    Seely AJE, Newman K, Ramchandani R, Herry C, Scales N, Hudek N, Brehaut J, Jones D, Ramsay T, Barnaby D, Fernando S, Perry J, Dhanani S, Burns KEA. Roadmap for the evolution of monitoring: developing and evaluating waveform-based variability-derived artificial intelligence-powered predictive clinical decision support software tools.Crit Care. 2024 Dec 5;28(1):404. doi: 10.1186/s13054-024-05140-6.  

4.    Hryciw BN, Hudek N, Brehaut JC, Herry C, Scales N, Lee E, Sarti AJ, Burns KEA, Seely AJE. Extubation Advisor: Implementation and Evaluation of A Novel Extubation Clinical Decision Support Tool. J Intensive Care. Epub 2024 Oct 24. https://doi.org/10.1177/08850666241291524  

5.    Jones D, Ahmadzai Z, Seely AJE. Actionable adverse event monitoring and feedback to improve thoracic surgical care. Curr Chall Thorac Surg 2024 Aug 29;6:18 doi: 10.21037/ccts-21   

Artificial intelligence and data science; Critical care; Quality Improvement