Solomon I, O’Reilly, Ionescu L, Alphonse RS, Rajabali S, Zhong S, Vadivel A, Shelley WC, Yoder MC, Thébaud B
. Functional differences between placental micro- and macrovascular endothelial colony-forming cells. Stem Cells Transl Med
. 2016 Mar;5(3):291-300.
Alphonse RS, Vadivel A, Zhong S, McConaghy S, Ohls R, Yoder MC, Thébaud B
. The isolation and culture of endothelial colony-forming cells from human and rat lungs. Nat Protoc
. 2015 Nov;10(11):1697-708.
Alphonse RS, Vadivel A, Fung M, Shelley WC, Critser PJ, Ionescu L, O'Reilly M, Ohls RK, McConaghy S, Eaton F, Zhong S, Yoder M, Thébaud B
. Existence, functional impairment and lung repair potential of endothelial colony forming cells in oxygen-induced arrested alveolar growth. Circulation
. 2014 May 27;129(21):2144-57.
Pierro M, Ionescu L, Montemurro T, Vadivel A, Weissmann G, Oudit G, Emery D, Bodiga S, Eaton F, Péault B, Mosca F, Lazzari L, Thébaud B
. Short-term, long-term and paracrine effect of human umbilical cord-derived stem cells in lung injury prevention and repair in experimental bronchopulmonary dysplasia. Thorax
. 2013 May;68(5):475-84. doi: 10.1136/thoraxjnl-2012-202323.
Luong C, Rey-Perra J, Vadivel A, Gilmour G, Sauve Y, Koonen D, Walker D, Todd KG, Gressens P, Kassiri Z, Nadeem K, Morgan B, Eaton F, Dyck JR, Archer SL, Thébaud B
. Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia. Circulation
. 2011 May 17;123(19):2120-31.
van Haaften T, Byrne R, Bonnet S, Rochefort GY, Akabutu J, GJ Rey-Parra, Bouchentouf M, Galipeau J, Haromy A, Eaton F, Chen M, Hashimoto K, Abley D, Korbutt G, Archer SL, Thébaud B
. Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med
. 2009; 180(11):1131-42.
, Ladha F, Michelakis E, Sawika M, Thurston G, Eaton F, Hashimoto K, Harry G, Haromy A, Korbutt G, Archer SL. Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization. Circulation
. 2005 Oct 18;112(16):2477-86.
Current lab members:
Arul Vadivel, Senior Research Associate
Liqun Xu, Senior Research Technician
Shumei Zhong, Research Technician
Chanèle Cyr-Depauw, Research Technician
Mehdi Shafa, Postdoctoral Fellow
Lars Mense, Clinical Research Fellow
Marissa Lithopoulos, PhD candidate
Graduate/Postdoctoral fellow opportunity:
Xplore Lab (xplorelab.ca) is currently seeking a highly self-motivated PhD or postdoc to work with hiPSCs to develop new therapies for genetic lung diseases. The candidate must
have excellent expertise in genetics, molecular biology, cell culture, iPSC biology with some experience in animal surgical procedures. Interested individuals should submit a brief description of their research experience, career goals, and motivation to join Xplore along with their full CV as a single PDF via email to email@example.com