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Cancer biotherapeutics

Biologically based therapeutics, which include oncolytic viruses and immune cell therapies, are among the most promising cancer treatments to emerge over the last decade. While different biotherapeutics function in different ways, one thing they have in common is the ability to mobilize and activate the body's natural defence mechanisms (the immune system) to attack cancer cells. Researchers at The Ottawa Hospital are leading the way in this area of research, with a number of world-first clinical trials and projects.

Research News


The Ottawa Hospital and uOttawa launch new cancer immunotherapy research projects with funding from BioCanRx
September 22, 2020 - BioCanRx, Canada’s Immunotherapy Network, today announced funding of $10M for 14 cancer immunotherapy research projects and eight core and biomanufacturing facilities across the country. Researchers at The Ottawa Hospital (TOH) and the University of
Virus and targeted drug synergize to fight cancer in mice
August 26, 2020 - While some cancer cells can be killed quickly by a single drug, the reality for patients is that multiple therapies are often required, especially if resistance develops. A new study led by Dr. Jean-Simon Diallo reveals for the first time that two pr
Protecting cancer patients from COVID-19
July 8, 2020 - In the race to find new ways to prevent and treat COVID-19, Canadian researchers have launched an innovative clinical trial focussed on strengthening the immune system for one of the most vulnerable populations – cancer patients.
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Atkins, Harold
MD, FRCPC
Scientist
(Cancer Therapeutics)
Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Cancer, Multiple sclerosis, Myasthenia gravis, Stiff person syndrome Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical trials, Immunotherapy, Oncolytic viruses, Regenerative medicine, Stem cells, Translational research, Transplantation, Viral therapy
Auer, Rebecca
MD, MSc, FRCSC
Senior Scientist
(Cancer Therapeutics)
Cancer, Colorectal cancer, Ovarian cancer, Pancreatic cancer Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical research, Clinical trials, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Peri-operative medicine, Quality Improvement, Surgery, Translational research, Viral therapy
Bell, John
PhD
Senior Scientist
(Cancer Therapeutics)
Cancer, COVID-19 Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Immunization, Immunotherapy, Oncolytic viruses, Translational research, Viral therapy
Diallo, Jean-Simon
PhD
Senior Scientist
(Cancer Therapeutics)
Cancer, COVID-19, Infectious disease Basic research, Cancer biotherapeutics, Cancer immunotherapy, Drug development, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
Ilkow, Carolina
PhD
Scientist
(Cancer Therapeutics)
Breast cancer, COVID-19, Ovarian cancer, Pancreatic cancer Basic research, Cancer biotherapeutics, Cancer immunotherapy, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
Kekre, Natasha
BSc, MD, MPH, FRCPC
Associate Scientist
(Clinical Epidemiology)
Blood cancer, Cancer Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical trials, Epidemiology, Immunotherapy, Stem cells, Translational research, Transplantation, Viral therapy
Lorimer, Ian
PhD
Senior Scientist
(Cancer Therapeutics)
Brain and neuromuscular disease, Brain cancer, Cancer Basic research, Cancer biotherapeutics, Cell therapy, Disease models, Molecular and cellular biology, Translational research
Vanderhyden, Barbara
PhD
Senior Scientist
(Cancer Therapeutics)
Cancer, Infertility, Ovarian cancer, Women's health Basic research, Bioinformatics, Biomarkers, Cancer biotherapeutics, Disease models, Drug development, Epigenetics, Gene expression, Genomics, Immunotherapy, Model organisms, Molecular and cellular biology, Oncolytic viruses, Stem cells, Transgenic/knockout models, Translational research, Viral therapy