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Cancer biotherapeutics

Biologically based therapeutics, which include oncolytic viruses and immune cell therapies, are among the most promising cancer treatments to emerge over the last decade. While different biotherapeutics function in different ways, one thing they have in common is the ability to mobilize and activate the body's natural defence mechanisms (the immune system) to attack cancer cells. Researchers at The Ottawa Hospital are leading the way in this area of research, with a number of world-first clinical trials and projects.

Research News


Protecting cancer patients from COVID-19
July 8, 2020 - In the race to find new ways to prevent and treat COVID-19, Canadian researchers have launched an innovative clinical trial focussed on strengthening the immune system for one of the most vulnerable populations – cancer patients.
Could biotherapeutics be the next revolution in cancer treatment?
February 20, 2020 - From helping the body’s own immune system better detect and fight cancer, to treating cancer with immune cells, viruses and vaccines, The Ottawa Hospital is conducting cutting-edge research that could transform cancer care right here at home and arou
Viral therapy for cancer: Frequently asked questions from patients and families
October 1, 2019 - What is viral therapy for cancer? Viral therapy for cancer, also called oncolytic viral therapy or viral immunotherapy, makes use of viruses to treat cancer.
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Atkins, Harold
MD, FRCPC
Scientist
(Cancer Therapeutics)
Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Cancer, Multiple sclerosis, Myasthenia gravis, Stiff person syndrome Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical trials, Immunotherapy, Oncolytic viruses, Regenerative medicine, Stem cells, Translational research, Transplantation, Viral therapy
Auer, Rebecca
MD, MSc, FRCSC
Senior Scientist
(Cancer Therapeutics)
Cancer, Colorectal cancer, Ovarian cancer, Pancreatic cancer Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical research, Clinical trials, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Peri-operative medicine, Quality Improvement, Surgery, Translational research, Viral therapy
Bell, John
PhD
Senior Scientist
(Cancer Therapeutics)
Cancer, COVID-19 Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Immunization, Immunotherapy, Oncolytic viruses, Translational research, Viral therapy
Diallo, Jean-Simon
PhD
Senior Scientist
(Cancer Therapeutics)
Cancer, COVID-19, Infectious disease Basic research, Cancer biotherapeutics, Cancer immunotherapy, Drug development, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
Ilkow, Carolina
PhD
Scientist
(Cancer Therapeutics)
Breast cancer, COVID-19, Ovarian cancer, Pancreatic cancer Basic research, Cancer biotherapeutics, Cancer immunotherapy, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
Kekre, Natasha
BSc, MD, MPH, FRCPC
Associate Scientist
(Clinical Epidemiology)
Blood cancer, Cancer Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical trials, Epidemiology, Immunotherapy, Stem cells, Translational research, Transplantation, Viral therapy
Lorimer, Ian
PhD
Senior Scientist
(Cancer Therapeutics)
Brain and neuromuscular disease, Brain cancer, Cancer Basic research, Cancer biotherapeutics, Cell therapy, Disease models, Molecular and cellular biology, Translational research
Vanderhyden, Barbara
PhD
Senior Scientist
(Cancer Therapeutics)
Cancer, Infertility, Ovarian cancer, Women's health Basic research, Bioinformatics, Biomarkers, Cancer biotherapeutics, Disease models, Drug development, Epigenetics, Gene expression, Genomics, Immunotherapy, Model organisms, Molecular and cellular biology, Oncolytic viruses, Stem cells, Transgenic/knockout models, Translational research, Viral therapy