Shi Wu Wen
Senior Scientist, Methodological and Implementation Research
Ottawa Hospital Research Institute
Associate Director, Education & Training, Clinical Epidemiology Program
Ottawa Hospital Research Institute
Professor, Department of Obstetrics & Gynecology
University of Ottawa
Professor, Department of Epidemiology and Community Medicine
University of Ottawa
Research Interests
Coming from Health Canada in 2001, Dr. Wen has worked with Dr. Mark Walker, to create an internationally recognized program of research in perinatal epidemiology. The focus of this program is fetal origins of adult disease, perinatal environmental epidemiology, and global perinatal health. In 2009 they were awarded a $6.5 million grant to study the effects of folic acid supplementation in decreasing the risk of pre-eclampsia. In 2016 they were awarded a $ 9.5 million CIHR foundation program grant to conduct epidemiologic studies to improve maternal and child health. In the past two decades, Dr. Wen has served for the Ottawa Hospital Research Ethics Board and various committee meetings at the Department of Obstetrics and Gynecology and School of Epidemiology and Public Health, University of Ottawa.
Dr. Wen has been teaching research methodology and epidemiologic principles at the undergraduate, post-graduate and fellowship levels. He has been invited to give lectures in the National Institute of Child Health and Human Development, Thomas Jefferson University, National University of Taiwan, McGill University, and several key medical schools in China.
Dr. Wen has published over 410 peer-reviewed articles in numerous top tier journals.
Brief Biography
Dr. Shi Wu Wen is a Senior Scientist in the Methodological & Implementation Research Program at the Ottawa Hospital Research Institute, Professor of Department of Obstetrics and Gynecology and of School of Epidemiology and Public Health, Faculty of Medicine, and member of the Faculty of Graduate Studies at the University of Ottawa, and Visiting Professor of Anhui Medical University and Central-South University in China.
Selected Publications
1. Wen, S. W., Zeng, N., Krewski, D., & Walker, M. C. (2024). When results from clinical trials are different from observational studies. Journal of clinical epidemiology, 111573. Advance online publication. https://doi.org/10.1016/j.jclinepi.2024.111573
2. Wen, S. W., Salman, M., Zeng, N., & Walker, M. C. (2024). Screening for diseases versus screening for health status. Journal of clinical epidemiology, 111650. Advance online publication. https://doi.org/10.1016/j.jclinepi.2024.111650
3. Zhou L, Qiu W, Wang J, Zhao A, Zhou C, Sun T, Xiong Z, Cao P, Shen W, Chen J, Lai X, Zhao LH, Wu Y, Li M, Qiu F, Yu Y, Xu ZZ, Zhou H, Jia W, Liao Y, Retnakaran R, Krewski D, Wen SW, Clemente JC, Chen T, Xie RH, He Y. Effects of vaginal microbiota transfer on the neurodevelopment and microbiome of cesarean-born infants: A blinded randomized controlled trial. Cell Host Microbe. 2023 Jul 12;31(7):1232-1247.e5. doi: 10.1016/j.chom.2023.05.022.
4. Corsi DJ, Donelle J, Sucha E, Hawken S, Hsu H, El-Chaâr D, Bisnaire L, Fell D, Wen SW, Walker M. Maternal cannabis use in pregnancy and child neurodevelopmental outcomes. Nat Med. 2020 Oct;26(10):1536-1540. doi: 10.1038/s41591-020-1002-5. Epub 2020 Aug 10. PMID: 32778828.
5. Wen SW*, Miao Q, Taljaard M, Lougheed J, Gaudet L, Davies M, Lanes A, Leader A, Corsi DJ, Sprague AE, Walker M. Associations of Assisted Reproductive Technology and Twin Pregnancy With Risk of Congenital Heart Defects. JAMA Pediatr. 2020 May 1;174(5):446-454. doi: 10.1001/jamapediatrics.2019.6096. PMID: 32091547; PMCID: PMC7042937.