New scientist profile: Dr. Gregory Hundemer wants to improve personalized medicine for high blood pressure

January 30, 2019

Dr. Gregory HundemerHigh blood pressure is commonly associated with age, diet, exercise and smoking. However, sometimes a hormonal imbalance is to blame. In these cases, diagnosis is more difficult and the health risks are greater, so Dr. Gregory Hundemer hopes to develop better and more personalized approaches. He wants to see whether it would be cost-effective to screen everyone with high blood pressure for hyperaldosteronism, the overproduction of the hormone aldosterone which affects approximately one in five of people with medication-resistant hypertension. People with this condition are at higher risk of heart attack and stroke. Some research suggests that the standard treatment for this hormone condition, called mineralocorticoid receptor (MR) antagonist therapy, may not work as well as previously thought. Dr. Hundemer also plans to investigate new biomarkers that can better show whether the treatment is working.

Dr. Hundemer was recently appointed as an associate scientist in the Clinical Epidemiology Program at the Ottawa Hospital Research Institute. He is a staff nephrologist at The Ottawa Hospital and an assistant professor at the University of Ottawa.

“I’d like to see a more personalized approach to treating people with high blood pressure by tailoring treatments to their specific conditions,” said Dr. Hundemer.

Research at The Ottawa Hospital led by scientists like Dr. Hundemer is possible because of generous donations to The Ottawa Hospital Foundation.

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Disease and research area tags: Vascular, heart and metabolic disease

Scientific Program tags: Inflammation and Chronic Disease Program