Ottawa research could reduce use of unnecessary medications in people with HIV

December 16, 2011

New research led by Dr. Jonathan Angel could spare many people with HIV from having to take unnecessary antibiotics associated with major side effects. A systematic review by Dr. Angel and his colleagues showed that when viral levels are suppressed, it is safe to stop taking antibiotics to prevent pneumonia, even if there has not been an adequate improvement in immune function as measured by CD4 count. This research could change the current clinical guidelines, which recommend a higher CD4 threshold and don’t take viral levels into account. This could improve health and quality of life for many people with HIV, while also saving money for individuals and the health-care system. See PLoS One for details.

Dr. Angel is supported by a Career Scientist Award from the Ontario HIV Treatment Network.