Scientific Publications Database

Article Title: Consensus Statement on the Classification of Tremors. From the Task Force on Tremor of the International Parkinson and Movement Disorder Society
Authors: Bhatia, Kailash P.; Bain, Peter; Bajaj, Nin; Elble, Rodger J.; Hallett, Mark; Louis, Elan D.; Raethjen, Jan; Stamelou, Maria; Testa, Claudia M.; Deuschl, Guenther
Journal: MOVEMENT DISORDERS Volume 33 Issue 1
Date of Publication:2018
Abstract:
Background: Consensus criteria for classifying tremor disorders were published by the International Parkinson and Movement Disorder Society in 1998. Subsequent advances with regard to essential tremor, tremor associated with dystonia, and other monosymptomatic and indeterminate tremors make a significant revision necessary.Objectives: Convene an international panel of experienced investigators to review the definition and classification of tremor.Methods: Computerized MEDLINE searches in January 2013 and 2015 were conducted using a combination of text words and MeSH terms: tremor, tremor disorders, essential tremor, dystonic tremor, and classification limited to human studies. Agreement was obtained using consensus development methodology during four in-person meetings, two teleconferences, and numerous manuscript reviews.Results: Tremor is defined as an involuntary, rhythmic, oscillatory movement of a body part and is classified along two axes: Axis 1clinical characteristics, including historical features (age at onset, family history, and temporal evolution), tremor characteristics (body distribution, activation condition), associated signs (systemic, neurological), and laboratory tests (electrophysiology, imaging); and Axis 2etiology (acquired, genetic, or idiopathic). Tremor syndromes, consisting of either isolated tremor or tremor combined with other clinical features, are defined within Axis 1. This classification scheme retains the currently accepted tremor syndromes, including essential tremor, and provides a framework for defining new syndromes.Conclusions: This approach should be particularly useful in elucidating isolated tremor syndromes and syndromes consisting of tremor and other signs of uncertain significance. Consistently defined Axis 1 syndromes are needed to facilitate the elucidation of specific etiologies in Axis 2. (C) 2017 International Parkinson and Movement Disorder Society.