Scientific Publications Database

Article Title: Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017
Authors: Smith, Toby O.; Mansfield, Michael; Hawker, Gillian A.; Hunter, David J.; March, Lyn M.; Boers, Maarten; Shea, Beverley J.; Christensen, Robin; Guillemin, Francis; Terwee, Caroline B.; Williamson, Paula R.; Roos, Ewa M.; Loeser, Richard F.; Schnitzer, Thomas J.; Kloppenburg, Margreet; Neogi, Tuhina; Ladel, Christoph H.; Kalsi, Gurdyal; Kaiser, Ulrike; Buttel, Thomas W.; Ashford, Anne E.; Mobasheri, Ali; Ardene, Nigel K.; Tennant, Alan; Hochberg, Marc C.; de Witel, Maarten; Tugwell, Peter; Conaghan, Philip G.
Journal: JOURNAL OF RHEUMATOLOGY Volume 46 Issue 8
Date of Publication:2019
Abstract:
Objective. To assess the uptake of the OMERACT-OARSI (Outcome Measures in Rheumatology-Osteoarthritis Research Society International) core outcome set (COS) domains in hip and/or knee osteoarthritis (OA) trials.Methods. There were 382 trials of hip and/or knee OA identified from the ClinicalTrial.gov registry from 1997 to 2017. Frequency of COS adoption was assessed by year and per 5-yearly phases.Results. COS adoption decreased from 61% between 1997 and 2001 to 38% between 2012 and 2016. Pain (95%) and physical function (86%) were most consistently adopted. Patient's global assessment (48%) was the principal missing domain.Conclusion. Limited adoption of the COS domains indicates that further consideration to improve uptake is required.