Scientific Publications Database

Article Title: Chordoma of the Head and Neck: A Review
Authors: Wasserman, Jason K.; Gravel, Denis; Purgina, Bibianna
Journal: HEAD & NECK PATHOLOGY Volume 12 Issue 2
Date of Publication:2018
Abstract:
Chordoma is a rare malignant bone tumor that can arise anywhere along the central neural axis and many involve head and neck sites, most commonly the skull base. The relative rarity of these tumors, combined with the complex anatomy of the head and neck, pose diagnostic challenges to pathologists. This article describes the pertinent clinical, pathologic, and molecular features of chordomas and describes how these features can be used to aid in formulating a differential diagnosis. Emphasis is placed on key diagnostic pitfalls and the importance of incorporating immunohistochemical information into the diagnosis.