Knowledge Synthesis Group

Selected Publications

A selected set of publications from KS Group team members from 2014-2020 is provided below. To find additional peer reviewed publications authored by members of the KS Group, please go to The Ottawa Hospital Library database and Pubmed (search by last name and initials).

Clinical Systematic Reviews

A scoping review of network meta-analyses assessing the efficacy and safety of complementary and alternative medicine interventions. Pratt M, Wieland S, Ahmadzai N, Butler C, Wolfe D, Pussagoda K, Skidmore B, Veroniki A, Rios P, Tricco AC, Hutton B. Syst Rev. 2020 Apr 30;9(1):97. doi: 10.1186/s13643-020-01328-3.

Drug induced pancreatitis: A systematic review of case reports to determine potential drug associations. Wolfe D, Kanji S, Yazdi F, Barbeau P, Rice D, Beck A, Butler C, Esmaeilisaraji L, Skidmore B, Moher D, Hutton B.PLoS One. 2020 Apr 17;15(4):e0231883. doi: 10.1371/journal.pone.0231883. eCollection 2020.

Screening for esophageal adenocarcinoma and precancerous conditions (dysplasia and Barrett's esophagus) in patients with chronic gastroesophageal reflux disease with or without other risk factors: two systematic reviews and one overview of reviews to inform a guideline of the Canadian Task Force on Preventive Health Care (CTFPHC). Hamel C, Ahmadzai N, Beck A, Thuku M, Skidmore B, Pussegoda K, Bjerre L, Chatterjee A, Dennis K, Ferri L, Maziak DE, Shea BJ, Hutton B, Little J, Moher D, Stevens A. Syst Rev. 2020 Jan 29;9(1):20. doi: 10.1186/s13643-020-1275-2.

Guidelines for the management of pregnant women with obesity: A systematic review. Simon A, Pratt M, Hutton B, Skidmore B, Fakhraei R, Rybak N, Corsi DJ, Walker M, Velez MP, Smith GN, Gaudet LM. Obes Rev. 2020 Mar;21(3):e12972. doi: 10.1111/obr.12972. Epub 2020 Jan 14.

Benefits and harms of medical cannabis: a scoping review of systematic reviews. Pratt M, Stevens A, Thuku M, Butler C, Skidmore B, Wieland LS, Clemons M, Kanji S, Hutton B. Syst Rev. 2019 Dec 10;8(1):320. doi: 10.1186/s13643-019-1243-x.

Methods for the early detection of drug-induced pancreatitis: a systematic review of the literature. Wolfe D, Kanji S, Yazdi F, Skidmore B, Moher D, Hutton B. BMJ Open. 2019 Nov 5;9(11):e027451. doi: 10.1136/bmjopen-2018-027451.

Canadian guideline for Parkinson disease. Grimes D, Fitzpatrick M, Gordon J, Miyasaki J, Fon EA, Schlossmacher M, Suchowersky O, Rajput A, Lafontaine AL, Mestre T, Appel-Cresswell S, Kalia SK, Schoffer K, Zurowski M, Postuma RB, Udow S, Fox S, Barbeau P, Hutton B. CMAJ. 2019 Sep 9;191(36):E989-E1004. doi: 10.1503/cmaj.181504.

A systematic review and network meta-analysis of existing pharmacologic therapies in patients with idiopathic sudden sensorineural hearing loss. Ahmadzai N, Kilty S, Cheng W, Esmaeilisaraji L, Wolfe D, Bonaparte JP, Schramm D, Fitzpatrick E, Lin V, Skidmore B, Moher D, Hutton B. PLoS One. 2019 Sep 9;14(9):e0221713. doi: 10.1371/journal.pone.0221713.

De-escalation of bone-modifying agents in patients with bone metastases from breast cancer: a systematic review and meta-analysis. Awan AA, Hutton B, Hilton J, Mazzarello S, Van Poznak C, Vandermeer L, Bota B, Stober C, Sienkiewicz M, Fergusson D, Shorr R, Clemons M. Breast Cancer Res Treat. 2019 Aug;176(3):507-517. doi: 10.1007/s10549-019-05265-1.

Comparative evaluation of group-based mindfulness-based stress reduction and cognitive behavioural therapy for the treatment and management of chronic pain: A systematic review and network meta-analysis. Khoo EL, Small R, Cheng W, Hatchard T, Glynn B, Rice DB, Skidmore B, Kenny S, Hutton B, Poulin PA.Evid Based Ment Health. 2019 Feb;22(1):26-35. doi: 10.1136/ebmental-2018-300062.

Incidence, causes, and consequences of preventable adverse drug reactions occurring in inpatients: A systematic review of systematic reviews. Wolfe D, Yazdi F, Kanji S, Burry L, Beck A, Butler C, Esmaeilisaraji L, Hamel C, Hersi M, Skidmore B, Moher D, Hutton B. PLoS One. 2018 Oct 11;13(10):e0205426. doi: 10.1371/journal.pone.0205426.

A systematic review of adverse events of rifapentine and isoniazid compared to other treatments for latent tuberculosis infection. Pease C, Hutton B, Yazdi F, Wolfe D, Hamel C, Barbeau P, Skidmore B, Alvarez GG. Pharmacoepidemiol Drug Saf. 2018 Mar 23.

The efficacy and safety of topical tranexamic acid: A systematic review and meta-analysis. Montroy J, Hutton B, Moodley P, Fergusson NA, Cheng W, Tinmouth A, Lavallée LT, Fergusson DA, Breau RH. Transfus Med Rev. 2018 Feb 19. pii: S0887-7963(17)30151-7.

The pharmacological and non-pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: A systematic review with network meta-analyses of randomised trials. Catalá-López F, Hutton B, Núñez-Beltrán A, Page MJ, Ridao M, Macías Saint-Gerons D, Catalá MA, Tabarés-Seisdedos R, Moher D. PLoS One. 2017 Jul 12;12(7):e0180355. doi: 10.1371/journal.pone.0180355. eCollection 2017.

Establishing core outcome sets for phenylketonuria (PKU) and medium-chain Acyl-CoA dehydrogenase (MCAD) deficiency in children: study protocol for systematic reviews and Delphi surveys. Potter BK, Hutton B, Clifford TJ, Pallone N, Smith M, Stockler S, Chakraborty P, Barbeau P, Garritty CM, Pugliese M, Rahman A, et al. Trials. 2017 Dec 19;18(1):603.

Efficacy and completion rates of rifapentine and isoniazid (3HP) compared to other treatment regimens for latent tuberculosis infection: a systematic review with network meta-analyses. Pease C, Hutton B, Yazdi F, Wolfe D, Hamel C, Quach P, Skidmore B, Moher D, Alvarez GG. BMC Infect Dis. 2017 Apr 11;17(1):265.

Sweet Solutions to Reduce Procedural Pain in Neonates: A Meta-analysis. Harrison D, Larocque C, Bueno M, Stokes Y, Turner L, Hutton B, Stevens B. Pediatrics. 2017 Jan;139(1). pii: e20160955. doi: 10.1542/peds.2016-0955.

Incidence, causes, and consequences of preventable adverse drug events: protocol for an overview of reviews. Hutton B, Kanji S, McDonald E, Yazdi F, Wolfe D, Thavorn K, Pepper S, Chapman L, Skidmore B, Moher D. Syst Rev. 2016 Dec 5;5(1):209.

Pharmacological interventions to improve sleep in hospitalised adults: a systematic review. Kanji S, Mera A, Hutton B, Burry L, Rosenberg E, MacDonald E, Luks V. BMJ Open. 2016 Jul 29;6(7):e012108.

Cardiovascular and Renal Outcomes of Renin-Angiotensin System Blockade in Adult Patients with Diabetes Mellitus: A Systematic Review with Network Meta-Analyses. Catalá-López F, Macías Saint-Gerons D, González-Bermejo D, Rosano GM, Davis BR, Ridao M, Zaragoza A, Montero-Corominas D, Tobías A, de la Fuente-Honrubia C, Tabarés-Seisdedos R, Hutton B. PLoS Med. 2016 Mar 8;13(3):e1001971.

Effectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Review. Hersi M, Stevens A, Quach P, Hamel C, Thavorn K, Garritty C, Skidmore B, Vallenas C, Norris SL, Egger M, Eremin S, Ferri M, Shindo N, Moher D. PLoS One. 2015 Oct 9;10(10):e0140290.

Methodologic Articles in Evidence Synthesis

A question of trust: can we build an evidence base to gain trust in systematic review automation technologies? O'Connor AM, Tsafnat G, Thomas J, Glasziou P, Gilbert SB, Hutton B. Syst Rev. 2019 Jun 18;8(1):143. doi: 10.1186/s13643-019-1062-0.

Knowledge Synthesis in Evidence-Based Medicine. Garritty C, Stevens A, Hamel C, Golfam M, Hutton B, Wolfe D. Semin Nucl Med. 2019 Mar;49(2):136-144. doi: 10.1053/j.semnuclmed.2018.11.006.

Treatment sequence network meta-analysis in Crohn's disease: a methodological case study. Varu A, Wilson FR, Dyrda P, Hazel M, Hutton B, Cameron C. Curr Med Res Opin. 2019 May;35(5):733-756. doi: 10.1080/03007995.2019.1580094.

A rapid research needs appraisal methodology to identify evidence gaps to inform clinical research priorities in response to outbreaks-results from the Lassa fever pilot. Sigfrid L, Moore C, Salam AP, Maayan N, Hamel C, Garritty C, Lutje V, Buckley B, Soares-Weiser K, Marshall R, Clarke M, Horby P. BMC Med. 2019 Jun 11;17(1):107. doi: 10.1186/s12916-019-1338-1.

Importance of assessing and adjusting for cross-study heterogeneity in network meta-analysis: a case study of psoriasis. Cameron C, Hutton B, Druchok C, McElligott S, Nair S, Schubert A, Situ A, Varu A, Villacorta R. J Comp Eff Res. 2018 Nov;7(11):1037-1051. doi: 10.2217/cer-2018-0065.

PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation. Tricco AC, Lillie E, Zarin W, O'Brien KK, Colquhoun H, Levac D, Moher D, Peters MDJ, Horsley T, Weeks L, Hempel S, Akl EA, Chang C, McGowan J, Stewart L, Hartling L, Aldcroft A, Wilson MG, Garritty C, Lewin S, Godfrey CM, Macdonald MT, Langlois EV, Soares-Weiser K, Moriarty J, Clifford T, Tunçalp Ö, Straus SE. Ann Intern Med. 2018 Oct 2;169(7):467-473. doi: 10.7326/M18-0850.

Developing WHO rapid advice guidelines in the setting of a public health emergency. Garritty CM, Norris SL, Moher D. J Clin Epidemiol. 2017 Feb;82:47-60.

The Importance of Considering Differences in Study Design in Network Meta-analysis: An Application Using Anti-Tumor Necrosis Factor Drugs for Ulcerative Colitis. Cameron C, Ewara E, Wilson FR, Varu A, Dyrda P, Hutton B, Ingham M. Med Decis Making. 2017 Nov;37(8):894-904.

Reporting guidance considerations from a statistical perspective: overview of tools to enhance the rigour of reporting of randomised trials and systematic reviews. Hutton B, Wolfe D, Moher D, Shamseer L. Evid Based Ment Health. 2017 May;20(2):46-52.

Rapid reviews for evidence synthesis. Catalá-López F, Stevens A, Garritty C, Hutton B. Med Clin (Barc). 2017 May 10;148(9):424-428.

The Devil Is in the Details: Incomplete Reporting in Preclinical Animal Research. Avey MT, Moher D, Sullivan KJ, Fergusson D, Griffin G, Grimshaw JM, Hutton B, Lalu MM, Macleod M, Marshall J, Mei SH, Rudnicki M, Stewart DJ, Turgeon AF, McIntyre L; Canadian Critical Care Translational Biology Group. PLoS One. 2016 Nov 17;11(11):e0166733.

The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Hutton B, Salanti G, Caldwell DM, Chaimani A, Schmid CH, Cameron C, Ioannidis JP, Straus S, Thorlund K, Jansen JP, Mulrow C, Catalá-López F, Gøtzsche PC, Dickersin K, Boutron I, Altman DG, Moher D. Ann Intern Med. 2015 Jun 2;162(11):777-84.

Clinical practice guidelines and consensus statements in oncology--an assessment of their methodological quality. Jacobs C, Graham ID, Makarski J, Chassé M, Fergusson D, Hutton B, Clemons M. PLoS One. 2014 Oct 17;9(10):e110469.

A Microsoft-Excel-based tool for running and critically appraising network meta-analyses--an overview and application of NetMetaXL. Brown S, Hutton B, Clifford T, Coyle D, Grima D, Wells G, Cameron C. Syst Rev. 2014 Sep 29;3:110. doi: 10.1186/2046-4053-3-110.