Knowledge Synthesis Group

Selected Publications

A selected set of publications from KS Group team members from 2014-2018 is provided below. To find additional peer reviewed publications authored by members of the KS Group, please go to The Ottawa Hospital Library database and Pubmed (search by last name and initials).

Clinical Systematic Reviews

A systematic review of adverse events of rifapentine and isoniazid compared to other treatments for latent tuberculosis infection. Pease C, Hutton B, Yazdi F, Wolfe D, Hamel C, Barbeau P, Skidmore B, Alvarez GG. Pharmacoepidemiol Drug Saf. 2018 Mar 23.

The efficacy and safety of topical tranexamic acid: A systematic review and meta-analysis. Montroy J, Hutton B, Moodley P, Fergusson NA, Cheng W, Tinmouth A, Lavallée LT, Fergusson DA, Breau RH. Transfus Med Rev. 2018 Feb 19. pii: S0887-7963(17)30151-7.

The pharmacological and non-pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: A systematic review with network meta-analyses of randomised trials. Catalá-López F, Hutton B, Núñez-Beltrán A, Page MJ, Ridao M, Macías Saint-Gerons D, Catalá MA, Tabarés-Seisdedos R, Moher D. PLoS One. 2017 Jul 12;12(7):e0180355. doi: 10.1371/journal.pone.0180355. eCollection 2017.

Establishing core outcome sets for phenylketonuria (PKU) and medium-chain Acyl-CoA dehydrogenase (MCAD) deficiency in children: study protocol for systematic reviews and Delphi surveys. Potter BK, Hutton B, Clifford TJ, Pallone N, Smith M, Stockler S, Chakraborty P, Barbeau P, Garritty CM, Pugliese M, Rahman A, et al. Trials. 2017 Dec 19;18(1):603.

Efficacy and completion rates of rifapentine and isoniazid (3HP) compared to other treatment regimens for latent tuberculosis infection: a systematic review with network meta-analyses. Pease C, Hutton B, Yazdi F, Wolfe D, Hamel C, Quach P, Skidmore B, Moher D, Alvarez GG. BMC Infect Dis. 2017 Apr 11;17(1):265.

Sweet Solutions to Reduce Procedural Pain in Neonates: A Meta-analysis. Harrison D, Larocque C, Bueno M, Stokes Y, Turner L, Hutton B, Stevens B. Pediatrics. 2017 Jan;139(1). pii: e20160955. doi: 10.1542/peds.2016-0955.

Incidence, causes, and consequences of preventable adverse drug events: protocol for an overview of reviews. Hutton B, Kanji S, McDonald E, Yazdi F, Wolfe D, Thavorn K, Pepper S, Chapman L, Skidmore B, Moher D. Syst Rev. 2016 Dec 5;5(1):209.

Pharmacological interventions to improve sleep in hospitalised adults: a systematic review. Kanji S, Mera A, Hutton B, Burry L, Rosenberg E, MacDonald E, Luks V. BMJ Open. 2016 Jul 29;6(7):e012108.

Cardiovascular and Renal Outcomes of Renin-Angiotensin System Blockade in Adult Patients with Diabetes Mellitus: A Systematic Review with Network Meta-Analyses. Catalá-López F, Macías Saint-Gerons D, González-Bermejo D, Rosano GM, Davis BR, Ridao M, Zaragoza A, Montero-Corominas D, Tobías A, de la Fuente-Honrubia C, Tabarés-Seisdedos R, Hutton B. PLoS Med. 2016 Mar 8;13(3):e1001971.

Effectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Review. Hersi M, Stevens A, Quach P, Hamel C, Thavorn K, Garritty C, Skidmore B, Vallenas C, Norris SL, Egger M, Eremin S, Ferri M, Shindo N, Moher D. PLoS One. 2015 Oct 9;10(10):e0140290.

Effectiveness of brief interventions as part of the Screening, Brief Intervention and Referral to Treatment (SBIRT) model for reducing the nonmedical use of psychoactive substances: a systematic review. Young MM, Stevens A, Galipeau J, Pirie T, Garritty C, Singh K, Yazdi F, Golfam M, Pratt M, Turner L, Porath-Waller A, Arratoon C, Haley N, Leslie K, Reardon R, Sproule B, Grimshaw J, Moher D. Syst Rev. 2014 May 24;3:50.

Methodologic Articles in Evidence Synthesis

Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies: The PRISMA-DTA Statement. McInnes MDF, Moher D, Thombs BD, McGrath TA, Bossuyt PM; the PRISMA-DTA Group, Clifford T, Cohen JF, Deeks JJ, Gatsonis C, Hooft L, Hunt HA, Hyde CJ, Korevaar DA, Leeflang MMG, Macaskill P, Reitsma JB, Rodin R, Rutjes AWS, Salameh JP, Stevens A, Takwoingi Y, Tonelli M, Weeks L, Whiting P, Willis BH. JAMA. 2018 Jan 23;319(4):388-396.

Evaluations of the uptake and impact of the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) Statement and extensions: a scoping review. Page MJ, Moher D. Syst Rev. 2017 Dec 19;6(1):263.

Reproducible research practices are underused in systematic reviews of biomedical interventions. Page MJ, Altman DG, Shamseer L, McKenzie JE, Ahmadzai N, Wolfe D, Yazdi F, Catalá-López F, Tricco AC, Moher D. J Clin Epidemiol. 2018 Feb;94:8-18.

Recommendations for reporting of systematic reviews and meta-analyses of diagnostic test accuracy: a systematic review. McGrath TA, Alabousi M, Skidmore B, Korevaar DA, Bossuyt PMM, Moher D, Thombs B, McInnes MDF. Syst Rev. 2017 Oct 10;6(1):194.

AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C, Moran J, Moher D, Tugwell P, Welch V, Kristjansson E, Henry DA. BMJ. 2017 Sep 21;358:j4008.

Systematic review adherence to methodological or reporting quality. Pussegoda K, Turner L, Garritty C, Mayhew A, Skidmore B, Stevens A, Boutron I, Sarkis-Onofre R, Bjerre LM, Hróbjartsson A, Altman DG, Moher D. Syst Rev. 2017 Jul 19;6(1):131.

Developing WHO rapid advice guidelines in the setting of a public health emergency. Garritty CM, Norris SL, Moher D. J Clin Epidemiol. 2017 Feb;82:47-60.

The Importance of Considering Differences in Study Design in Network Meta-analysis: An Application Using Anti-Tumor Necrosis Factor Drugs for Ulcerative Colitis. Cameron C, Ewara E, Wilson FR, Varu A, Dyrda P, Hutton B, Ingham M. Med Decis Making. 2017 Nov;37(8):894-904.

Reporting guidance considerations from a statistical perspective: overview of tools to enhance the rigour of reporting of randomised trials and systematic reviews. Hutton B, Wolfe D, Moher D, Shamseer L. Evid Based Ment Health. 2017 May;20(2):46-52.

Enhancing the usability of systematic reviews by improving the consideration and description of interventions. Hoffmann TC, Oxman AD, Ioannidis JP, Moher D, Lasserson TJ, Tovey DI, Stein K, Sutcliffe K, Ravaud P, Altman DG, Perera R, Glasziou P. BMJ. 2017 Jul 20;358:j2998.

Rapid reviews for evidence synthesis. Catalá-López F, Stevens A, Garritty C, Hutton B. Med Clin (Barc). 2017 May 10;148(9):424-428.

Cochrane Rapid Reviews Methods Group to play a leading role in guiding the production of informed high-quality, timely research evidence syntheses. Garritty C, Stevens A, Gartlehner G, King V, Kamel C; Cochrane Rapid Reviews Methods Group. Syst Rev. 2016 Oct 28;5(1):184.

The Devil Is in the Details: Incomplete Reporting in Preclinical Animal Research. Avey MT, Moher D, Sullivan KJ, Fergusson D, Griffin G, Grimshaw JM, Hutton B, Lalu MM, Macleod M, Marshall J, Mei SH, Rudnicki M, Stewart DJ, Turgeon AF, McIntyre L; Canadian Critical Care Translational Biology Group. PLoS One. 2016 Nov 17;11(11):e0166733.

The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Hutton B, Salanti G, Caldwell DM, Chaimani A, Schmid CH, Cameron C, Ioannidis JP, Straus S, Thorlund K, Jansen JP, Mulrow C, Catalá-López F, Gøtzsche PC, Dickersin K, Boutron I, Altman DG, Moher D. Ann Intern Med. 2015 Jun 2;162(11):777-84.

Rapid review programs to support health care and policy decision making: a descriptive analysis of processes and methods. Polisena J, Garritty C, Kamel C, Stevens A, Abou-Setta AM. Syst Rev. 2015 Mar 14;4:26. doi: 10.1186/s13643-015-0022-6.

Clinical practice guidelines and consensus statements in oncology--an assessment of their methodological quality. Jacobs C, Graham ID, Makarski J, Chassé M, Fergusson D, Hutton B, Clemons M. PLoS One. 2014 Oct 17;9(10):e110469.

A Microsoft-Excel-based tool for running and critically appraising network meta-analyses--an overview and application of NetMetaXL. Brown S, Hutton B, Clifford T, Coyle D, Grima D, Wells G, Cameron C. Syst Rev. 2014 Sep 29;3:110. doi: 10.1186/2046-4053-3-110.

Journalology and Research Integrity

Assessing scientists for hiring, promotion, and tenure. Moher D, Naudet F, Cristea IA, Miedema F, Ioannidis JPA, Goodman SN. PLoS Biol. 2018 Mar 29;16(3):e2004089.

Canadian funders and institutions are lagging on reporting results of clinical trials. Cobey KD, Fergusson D, Moher D. CMAJ. 2017 Oct 23;189(42):E1302-E1303.

Stop this waste of people, animals and money. Moher D, Shamseer L, Cobey KD, Lalu MM, Galipeau J, Avey MT, Ahmadzai N, Alabousi M, Barbeau P, Beck A, Daniel R, Frank R, Ghannad M, Hamel C, Hersi M, Hutton B, Isupov I, McGrath TA, McInnes MDF, Page MJ, Pratt M, Pussegoda K, Shea B, Srivastava A, Stevens A, Thavorn K, van Katwyk S, Ward R, Wolfe D, Yazdi F, Yu AM, Ziai H. Nature. 2017 Sep 6;549(7670):23-25.

Illegitimate journals scam even senior scientists. Cobey C. Nature. 2017 Sep 6;549(7670):7. doi: 10.1038/549007a.

Core competencies for scientific editors of biomedical journals: consensus statement. Moher D, Galipeau J, Alam S, Barbour V, Bartolomeos K, Baskin P, Bell-Syer S, Cobey KD, Chan L, Clark J, Deeks J, Flanagin A, Garner P, Glenny AM, Groves T, Gurusamy K, Habibzadeh F, Jewell-Thomas S, Kelsall D, Lapeña JF Jr, MacLehose H, Marusic A, McKenzie JE, Shah J, Shamseer L, Straus S, Tugwell P, Wager E, Winker M, Zhaori G. BMC Med. 2017 Sep 11;15(1):167.

Potential predatory and legitimate biomedical journals: can you tell the difference? A cross-sectional comparison. Shamseer L, Moher D, Maduekwe O, Turner L, Barbour V, Burch R, Clark J, Galipeau J, Roberts J, Shea BJ. BMC Med. 2017 Mar 16;15(1):28. doi: 10.1186/s12916-017-0785-9.

A scoping review of competencies for scientific editors of biomedical journals. Galipeau J, Barbour V, Baskin P, Bell-Syer S, Cobey K, Cumpston M, Deeks J, Garner P, MacLehose H, Shamseer L, Straus S, Tugwell P, Wager E, Winker M, Moher D. BMC Med. 2016; 14: 16. Published online 2016 Feb 2. doi: 10.1186/s12916-016-0561-2