Current Funding

Total funding: $110,821,850
Total lifetime funding as Principal Investigator or Co-Principal Investigator: $35,654,673
*unless otherwise stated, Dr. Fergusson's role is a Co-Investigator

Cellular Immunotherapy for Septic Shock (CISS): Research to Move Stem Cells Through the Clinical Pipeline
Principal Investigator: Lauralyn McIntyre
Funder: Ontario Institute for Regenerative Medicine (OIRM)
Program: Disease Team Project
Total awarded: $370,000
04/2018-03/2020

INCuBATOR: New Cell Treatments for Lung Injury in Babies – Getting research faster and safer into patients.
Principal Investigator: Bernard Thebaud
Funder: Ontario Institute for Regenerative Medicine (OIRM)
Program: Accellerator grant
Total awarded: $100,000
04/2018-03/2019

PRICE 2: A phase 3 randomized controlled trial of phlebotomy resulting in controlled hypovolemia to prevent blood loss in major hepatic resections
Principal Investigator: Guillaume Martel
Funder: CIHR
Program: Project Grant
Total funding: $497,252
04/2018-03/2022

Updating Needs and Network Meta-analyses for the Canadian Guidelines for Chronic Rhinosinusitis
Principal Investigators: Martin Yvon Desrosiers, Brian Hutton, Shaun Kilty
Funder: CIHR
Program: Project Grant
Total funding: $187,425
04/2018-09/2020

Microbiome-Based Precision Medicine in Inflammatory Bowel Disease
Principal Investigators: Alan Stintzi and David Mack
Funder: Genome Canada
Program: Large-Scale Applied Research Project Competition
Total funding: $4,469,716
04/2018-03/2022

Understanding decision making in organ donation: a national study
Principal Investigators: Michaël Chassé, Kimberly Jordison, Justin Presseau
Funder: CIHR
Program: Project Grant
Total awarded: $669,375
04/2018-03/2021

Endothelial Progenitor Cell Exosomes and MicroRNA Transfer as Therapy for Acute Kidney Injury
Principal Investigator: Kevin Burns
Funder: CIHR
Program: Project Grant
Total awarded: $742,050
04/2018-03/2023

Pathways of care and clinical outcomes following implementation of the new CCS guidelines: an interrupted time series analysis
Principal Investigators: Manoj Lalu and Daniel McIsaac
Funder: TOHAMO
Program: Innovation Fund
Total awarded: $99,841
04/2018-03/2019

Pilot Optimizing Transfusion Thresholds and Targets in Critically-ill Children with Anaemia (P-OpTTTICCA): a pilot trial for a large innovative international parallel open-label non-inferiority randomised controlled trial and a ’study within a trial’ to describe the use of physiologic markers to guide red cell transfusions.
Prinicipal Investigators: Jacques Lacroix, Marisa Tucci, Simon Stanworth, Stéphane Leteurtre
Funder: National Institutes of Health (NIH, USA)
Total Awarded : $220,000 US
04/2018-03/2019

Intravenous immune globulin in septic shock: A Canadian national census
Principal Investigators: Faisal Siddiqui (NPI), Murdoch Leeies, Ryan Zarychanski
Funder: Anesthesia Oversight Committee Operating Grant. Winnipeg, Manitoba
Total awarded: $10,000
03/2018-02/2020

Cellular Immunotherapy in Septic Shock: A Meeting to Develop a Stem Cell in Sepsis International Collaborative Network
Principal Investigators: Dean Fergusson & Lauralyn McIntyre
Funder: CIHR
Program: Planning and Dissemination Grant
Total awarded: $10,000
11/2017-10-2018

IMPRESS Canada: Improving Preclinical Reporting and Experimental Study deSign of Canadian cardiovascular researchers
Principal Investigator: Manoj Lalu
Funder: Canadian Vascular Network
Program: Dragon’s Den
Total Awarded: $50,000
07/2017-06/2019

Developing a framework for the ethical design and conduct of pragmatic trials to improve the quality and value of health care systems and practices
Principal Investigators: Dean Fergusson, Monica Taljaard, Charles Weijer Principal Knowledge User: Terry Klassen
Funder: CIHR
Program: Project Grant
Total awarded: $780,300
04/2017-03/2021

An innovative Trial Assessing Donor Sex on Recipient Mortality (iTADS)
Principal Investigators: Dean Fergusson, Michaël Chassé, Alan Tinmouth
Funder: CIHR
Program: Project Grant
Total awarded: $371,026
04/2017-03/2019

Critical Care Outcomes in Hematology Malignancy and Stem Cell Transplant
Principle Investigators: Laveena Munshi and Sangeeta Mehta
Funder: Leukemia and Lymphoma Society of Canada
Total awarded: $199,742.52
05/2017- 04/2019

Stem cell Therapy fOr Perioperative Myocardial Infarction (STOP-MI): The Ottawa EXCELerator
Principal Investigators: Dean Fergusson and Manoj Lalu
Funder: Department of Anesthesiology and Pain medicine, uOttawa
Program: University of Ottawa Anesthesiology and Pain Medicine Research (OUAPM) Grant competition
Total awarded: $27,500
05/2017 – 04/2018

Aneurysmal Subarachnoid Hemorrhage - Red Blood Cell Transfusion and Outcome (SAHaRA): A Randomized Controlled Trial
Principal Investigator: Shane English
Funder: CIHR
Program: Project Grant
Total awarded: $1,384,650
04/2017-03/2022

Heparin anticoagulation to improve outcomes in septic shock: The HALO International Phase II Trial
Principal Investigators: Dean Fergusson, Ryan Zarychanski, Anand Kumar
Funder: CIHR
Program: Project Grant
Total awarded: $631,125
04/2017-03/2020

Endothelial Progenitor Cell Exosomes and MicroRNA Transfer as Therapy for Acute Kidney Injury
Principal Investigator: Kevin Burns
Funder: CIHR
Program: Project Grant (Bridge funding)
Total awarded: $100, 000
04/2017-03/2018

Cellular Immunotherapy for Septic Shock (CISS): A Phase II Trial
Principal Investigators: Dean Fergusson and Lauralyn McIntyre
Funder: CIHR
Program: Project Grant (Bridge funding)
Total awarded: $100,000
04/2017-03/2018

Translational cancer immunotherapeutics: improving the design, analysis, and reporting of pre-clinical studies
Principal Investigator: Dean Fergusson
Funder: BioCanRx
Program: Clinical, Social & Economic Impact
Total awarded: $99,341
01/2017-12/2018

Getting better Outcomes with Chimeric Antigen Receptor T-cell therapy (GO-CART)
Principal Investigator: Dean Fergusson
Funder: BioCanRx
Program: Clinical, Social & Economic Impact
Total awarded: $80,668
01/2017-12/2018

Cellular Immunotherapy for Septic Shock (CISS): A Phase II Multicentre Clinical Trial
Principal Investigator: Lauralyn McIntyre
Funder: Stem Cell Network
Total awarded: $1,000,000
12/2016-12/2018

Optimizing a personalized infected cell vaccine (ICV) for peritoneal carcinomatosis
Principal Investigator: Rebecca Auer
Funder: BioCanRx
Program: Catalyst Program
Total awarded: $251,692
10/2016-09/2018

An epidemiologic research program to improve maternal and child health
Principal Investigators: Shi Wu Wen and Mark Walker
Funder: CIHR
Program: Foundation Scheme
Total awarded: $9,876,973
08/2016-07/2023

Optimal Practices in Critical Care Neurology and Trauma
Principal Investigator: Alexis Turgeon
Funder: CIHR
Program: Foundation Scheme
Total awarded: $1,891,003
07/2016-06/2021

Computed tomography perfusion for neurological death determination: a prospective Canadian multicenter diagnostic test study
Principal Investigators: Michaël Chassé and Jai Jai Shiva Shankar
Funder: CIHR
Program: Project Grant
Total awarded: $832,828
07/2016-06/2020

Transfusion in Traumatic Brain Injury Trial (TSiTBI Trial)
Principal Investigators: Dean Fergusson and Francois Lauzier
Funder: CIHR
Program: Project Grant
Total awarded: $1,490,000
07/2016-06/2021

Ethics, Efficiency and Patient Burden in Drug Development
Principal Investigator: Jonathan Kimmelman
Funder: CIHR
Program: Project Grant
Total awarded: $321,090
07/2016-06/2020

Endoscopic Polypectomy performed In Clinic for chronic rhinosinusitis with polyps: The EPIC multicenter randomised controlled trial
Principal Investigators: Dean Fergusson & Shaun Kilty
Funder: CIHR
Program: Project Grant
Total awarded: $210,716
07/2016-06/2018

StAtins for Venous Event Reduction in patients with venous thromboembolism (The SAVER Pilot Randomized Trial)
Principal Investigator: Marc Rodger
Funder: CIHR
Program: Project Grant
Total awarded: $424,298
07/2016-06/2019

Improving the quality of judgment in cancer therapeutics development
Principal Investigators: Dean Fergusson, Jonathan Kimmelman, Christopher McCabe
Funder: BioCanRx
Program: Clinical, Social and Economic Impact grant
Total awarded: $534,846
04/2016 - 03/2019

Sleep and Circadian Rhythms and Venous Thromboembolic Diseases Clinical Trials Grant (CanVECTOR)
Principal Investigators: Susan Kahn and Marc Rodger
Funder: CIHR
Program: ICRH Community Development Program Grant
Total awarded: $1,500,000
10/2015-09/2020

Development of a targeted oncolytic virus vaccine for the treatment of metastatic prostate cancer
Principal Investigator: John Bell
Funder: Prostate Cancer Canada
Program: Movember Team Grant
Total awarded: $4,990,498
07/2015-06/2020

Predicting and preventing the major vascular complications of surgery
Program Leader: PJ Devereaux
Funder: CIHR
Program: Foundation Scheme
Total awarded: $8,439,205
07/2015-06/2022

Promoting implementation of evidence-based care
Program Leader: Jeremy Grimshaw
Funder: CIHR
Program: Foundation Scheme
Total awarded: $2,128,006
07/2015-06/2022

Clinical translation of stem cell-based therapies for neonatal lung diseases
Program Leader: Bernard Thebaud
Funder: CIHR
Program: Foundation Scheme
Total awarded: $5,250,000
07/2015-06/2022

A Research Program to Improve Patient Outcomes in Kidney Transplantation
Program Leader: Gregory Knoll
Funder: CIHR
Program: Foundation Scheme
Total awarded: $3,871,800
07/2015-06/2022

Tranexamic acid during cystectomy trial (TACT)
Principal Investigator: Rodney Breau, Ilias Cagiannos, Franco Momoli
Funder: CIHR
Program: Operating
Total awarded: $359,168
07/2015-06/2018

Aneurysmal SubArachnoid Hemorrhage - Red Blood Cell Transfusion And Outcome (SAHaRA): a Pilot Randomized Controlled Trial
Principal Investigator: Shane English and Lauralyn McIntyre
Funder: CIHR
Program: Operating - Priority Announcement - Transfusion Science
Total awarded: $157,172
07/2015-06/2018

Myocardial Ischemia and Transfusion. The MINT Rollover Trial
Principal Investigators: Paul Hebert and Jeffery Carson
Role: Co-investigator
Funder: CIHR
Program: Operating Grant - Priority Announcement - Transfusion Science
Total awarded: $140,210
07/2015-06/2018