Publications
Selected Publications
1.
Gage BK, Liu JC, Innes BT, MacParland SA, McGilvray ID, Bader GD, Keller GM. Generation of Functional Liver Sinusoidal Endothelial Cells from Human Pluripotent Stem Cell-Derived Venous Angioblasts. Cell Stem Cell. (2020) 27(2): 254-269 e259.
Article.
- This study established the core mouse model used in the Gage lab where mouse liver vasculature (LSECs) are replaced by functionally mature hPSC-derived LSECs.
- Exploration of published scRNAseq data of hPSC-LSECs can be found collaboratively here with Dr. Gary Bader (U of Toronto).
2.
Gage BK, Merlin S, Olgasi C, Follenzi A, Keller GM. Therapeutic Correction of Hemophilia A by Transplantation of hPSC-derived Liver Sinusoidal Endothelial Cell Progenitors. Cell Rep. (2022) 39(1): 110621.
Article.
- This study developed a new higher yield differentiation protocol to make hPSC-derived venous endothelial cells with enhanced liver engraftment potential.
- In collaboration with Dr. Antonia Follenzi (Università, del Piemonte Orientale, Italy), this study also revealed that hPSC-VEC cell therapy can functionally correct severe bleeding phenotypes seen in Hemophilia A mice paving the way for future cell therapy development.
All Other Publications
Please see my
Google Scholar account.
Please see my ORCID.
0000-0002-6601-6369PubMed Listings