Daniel Coutu profile picture

Contact Information

Daniel Coutu, PhD
613-798-5555; 79048
dacoutu@ohri.ca

Daniel Coutu

Scientist, Regenerative Medicine Program
Ottawa Hospital Research Institute
Assistant Professor, Department of Cellular & Molecular Medicine
University of Ottawa
Research Chair, Regenerative Orthopedic Surgery
The Ottawa Hospital

Research Interests

Stem cells, bone, cartilage, tendons/ligaments, orthopedic surgery, imaging techniques, quantitative image analysis, hematopoiesis

Brief Biography

2013- 2018:
ETH Zürich (Basel, Switzerland)
Postdoctoral Fellow
Department of Biosystems Science and Engineering

2011- 2013:
Helmholtz Zentrum München (Munich, Germany)
Postdoctoral Fellow
Institute for Stem Cell Research

2004- 2011:
McGill University (Montreal, Canada)
Philosophiae Doctor (PhD)
Division of Experimental Medicine

2000-2004:
Université de Montréal (Montreal, Canada)
Baccalaureat ès sciences (BSc)
Sciences Biologiques (Microbiologie et Immunologie)

Selected Publications

1: Coutu DL, Kokkaliaris KD, Kunz L, Schroeder T. Multicolor quantitative
confocal imaging cytometry. Nat Methods. 2018 Jan;15(1):39-46. doi:
10.1038/nmeth.4503. Epub 2017 Nov 13. PubMed PMID: 29320487.

2: Coutu DL, Kokkaliaris KD, Kunz L, Schroeder T. Three-dimensional map of
nonhematopoietic bone and bone-marrow cells and molecules. Nat Biotechnol. 2017
Dec;35(12):1202-1210. doi: 10.1038/nbt.4006. Epub 2017 Nov 13. PubMed PMID:
29131149.

3: Hoppe PS, Schwarzfischer M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Moritz
N, Endele M, Filipczyk A, Gambardella A, Ahmed N, Etzrodt M, Coutu DL, Rieger MA,
Marr C, Strasser MK, Schauberger B, Burtscher I, Ermakova O, Bürger A, Lickert H,
Nerlov C, Theis FJ, Schroeder T. Early myeloid lineage choice is not initiated by
random PU.1 to GATA1 protein ratios. Nature. 2016 Jul 14;535(7611):299-302. doi:
10.1038/nature18320. PubMed PMID: 27411635.

4: Hoppe PS, Coutu DL, Schroeder T. Single-cell technologies sharpen up mammalian
stem cell research. Nat Cell Biol. 2014 Oct;16(10):919-27. doi: 10.1038/ncb3042.
Review. PubMed PMID: 25271480.

5: Coutu DL, Schroeder T. Probing cellular processes by long-term live
imaging--historic problems and current solutions. J Cell Sci. 2013 Sep 1;126(Pt
17):3805-15. doi: 10.1242/jcs.118349. Epub 2013 Aug 13. Review. PubMed PMID:
23943879.

Diseases, conditions and populations of interest


Aging; Arthritis; Autoimmune disease; Bleeding disorders; Blood cancer; Bone and joint degeneration; Bone and joint injuries; Chronic disease; Musculoskeletal conditions; Osteoporosis



Research and clinical approaches


3D printing; Basic research; Bioinformatics; Biomaterials; Cell therapy; Gene expression; Gene therapy; Genetics; Genomics; Imaging; Immunotherapy; Molecular and cellular biology; Proteomics; Regenerative medicine; Stem cells; Surgery; Systems biology; Transgenic/knockout models; Translational research