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Autoimmune disease

Autoimmune diseases occur when the body’s immune system mistakenly attacks its own tissues. The Ottawa Hospital is conducting cutting-edge research to improve our understanding of autoimmune diseases and develop better treatments.

Research News


Stem cell treatment for scleroderma improves quality of life
February 17, 2021 - When Dr. Nancy Maltez meets a patient with early severe systemic scleroderma, a rare autoimmune disease that hardens the skin and organs, she knows one of the best options is to reset their immune system using strong chemotherapy and a stem cell tran
New scientist profile: Dr. Angela Cheung’s patients inspire her to investigate rare liver diseases
January 27, 2021 - Dr. Angela Cheung understands why her patients with autoimmune liver diseases are frustrated. Little is known about these rare diseases, and treatments can often only delay, but not prevent, a liver transplant.
Are we using biologic therapy properly?
June 13, 2019 - The introduction of infliximab (Remicade), the first biologic therapy approved for the treatment of inflammatory bowel diseases (IBD), did not result in lower rates of hospitalizations or intestinal surgeries among patients living with IBD in Ontario
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Atkins, Harold
MD, FRCPC
Scientist
(Cancer Therapeutics)
Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Cancer, Multiple sclerosis, Myasthenia gravis, Stiff person syndrome Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical trials, Immunotherapy, Oncolytic viruses, Regenerative medicine, Stem cells, Translational research, Transplantation, Viral therapy
Coutu, Daniel
PhD
Scientist
(Regenerative Medicine)
Aging, Arthritis, Autoimmune disease, Bleeding disorders, Blood cancer, Bone and joint degeneration, Bone and joint injuries, Chronic disease, Musculoskeletal conditions, Osteoporosis 3D printing, Basic research, Bioinformatics, Biomaterials, Cell therapy, Gene expression, Gene therapy, Genetics, Genomics, Imaging, Immunotherapy, Molecular and cellular biology, Proteomics, Regenerative medicine, Stem cells, Surgery, Systems biology, Transgenic/knockout models, Translational research
Cowan, Juthaporn
MD, PhD, FRCPC
Associate Scientist
(Clinical Epidemiology)
Autoimmune disease, COVID-19, Infectious disease Immunization, Immunotherapy, Patient engagement
Santos, Marlise
MD (FRCPC), MSc, MPH
Clinician Investigator
(Clinical Epidemiology)
Alzheimer's, Anxiety, Ataxia, Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Brain and neuromuscular disease, Brain cancer, Cancer, Chronic disease, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Sickle cell anemia, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease Artificial intelligence and data science, Basic research, Behaviour, Biostatistics, Cancer biotherapeutics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews
Walker, Lisa
PhD, C.Psych
Clinician Investigator
(Neuroscience)
Anxiety, Autoimmune disease, Autoimmune diseases of the nervous system, Brain and neuromuscular disease, Dementia, Depression, Mental health, Multiple sclerosis Behaviour, Biomarkers, Clinical research, Exercise, Imaging, Psychology, Psychometrics, Rehabilitation, Stem cells, Systematic reviews, Translational research