Gerd Melkus profile picture

Contact Information

Gerd Melkus, PhD
613-798-5555 Ext. 12033
gmelkus@toh.on.ca

Civic Campus
1053 Carling Avenue, Room S52
Ottawa, Ontario, K1Y 4E9
Canada

Publications

Selected Publications



[01] Rakhra KS, Cárdenas-Blanco A, Melkus G, Schweitzer ME, Cameron IG, Beaulé PE. Is the T1ρ MRI Profile of Hyaline Cartilage in the Normal Hip Uniform? Clin Orthop Relat Res. 2014 Aug 1; [Epub ahead of print]

[02] Pinney JR, Melkus G, Cerchiari A, Hawkins J, Desai TA. Novel Functionalization of Discrete Polymeric Biomaterial Microstructures for Applications in Imaging and Three-Dimensional Manipulation. ACS Appl Mater Interfaces. 2014 Jul 28; [Epub ahead of print]

[03] Fuchs J, Melkus G, Borisjuk L, Jakob P. Tracking metabolite dynamics in plants via indirect 13C chemical shift imaging with an interleaved variable density acquisition weighted sampling pattern. Magn Reson Mater Phy. 2014 Jun 22; [Epub ahead of print] DOI 10.1007/s10334-014-0453-4

[04] Otto C, Klingelhöffer C, Biggemann L, Melkus G, Mörchel P, Jürgens C, Gahn S, Kämmerer U. Experimentelle Untersuchungen zur Verstoffwechselung von Ketonkörpern und Laktat durch Tumorzellen des Gastrointestinaltrakts. Aktuel Ernahrungsmed. 2014; 39: 51-59. [Article in German]

[05] Melkus G, Grabau M, Karampinos DC, Majumdar S. Ex vivo Porcine Model to Measure pH Dependence of gagCEST in the Inter-Vertebral Disc. Magn Reson Med. 2013 Jul 1. doi: 10.1002/mrm.24838. [Epub ahead of print]

[06] Karampinos DC, Melkus G, Baum T, Bauer JS, Rummeny EJ, Krug R. Bone marrow fat quantification in the presence of trabecular bone: Initial comparison between water-fat imaging and single-voxel MRS. Magn Reson Med. 2013 May 8. doi: 10.1002/mrm.24775. [Epub ahead of print]

[07] Raya JG, Melkus G, Adam-Neumair S, Dietrich O, Mützel E, Reiser MF, Putz R, Kirsch T, Jakob PM, Glaser C. Diffusion-Tensor Imaging of Human Articular Cartilage Specimens with Early Signs of Cartilage Damage. Radiology. 2013; 266: 831-841.

[08] Fuchs J, Neuberger T, Rolletschek H, Schiebold S, Nguyen TH, Borisjuk N, Melkus G, Börner A, Jakob P, Borisjuk L. A non-invasive platform for imaging and quantifying oil storage in sub-millimetre tobacco seed. Plant Physiol. 2013; 161: 583-593.

[09] Srikhum W, Nardo L, Karampinos DC, Melkus G, Poulos T, Steinbach LS, Link TM. Magnetic resonance imaging of ankle tendon pathology: benefits of additional axial short-tau inversion recovery imaging to reduce magic angle effects. Skeletal Radiol. 2013; 42: 499-510.

[10] Karampinos DC, Melkus G, Shepherd TM, Banerjee S, Saritas EU, Shankaranarayanan A, Hess CP, Link TM, Dillon WP, Majumdar S. Diffusion tensor imaging and T(2) relaxometry of bilateral lumbar nerve roots: feasibility of in-plane imaging. NMR Biomed. 2013 Jun; 26: 630-637.

[11] Samagh SP, Kramer EJ, Melkus G, Laron D, Bodendorfer BM, Natsuhara K, Kim HT, Liu X, Feeley BT. MRI quantification of fatty infiltration and muscle atrophy in a mouse model of rotator cuff tears. J Orthop Res. 2013; 31: 421-426.

[12] Ziener CH, Kampf T, Melkus G, Jakob PM, Schlemmer HP, Bauer WR. Signal evolution in the local magnetic field of a capillary - analogy to the damped driven harmonic oscillator. Magn Reson Imaging. 2012; 30: 540-553.

[13] Rolletschek H, Melkus G, Grafahrend-Belau E, Fuchs J, Heinzel N, Schreiber F, Jakob PM, Borisjuk L. Combined noninvasive imaging and modeling approaches reveal metabolic compartmentation in the barley endosperm. Plant Cell. 2011; 23: 3041-3054.

[14] Borisjuk L, Rolletschek H, Fuchs J, Melkus G, Neuberger T. Low and High Field Magnetic Resonance for in Vivo Analysis of Seeds. Materials. 2011, 4: 1426-1439.

[15] Raya JG, Arnoldi AP, Weber DL, Filidoro L, Dietrich O, Adam-Neumair S, Mützel E, Melkus G, Putz R, Reiser MF, Jakob PM, Glaser C. Ultra-high field diffusion tensor imaging of articular cartilage correlated with histology and scanning electron microscopy. MAGMA. 2011; 24: 247-258.

[16] Melkus G, Rolletschek H, Fuchs J, Radchuk V, Grafahrend-Belau E, Sreenivasulu N, Rutten T, Weier D, Heinzel N, Schreiber F, Altmann T, Jakob PM, Borisjuk L. Dynamic (13) C/(1) H NMR imaging uncovers sugar allocation in the living seed. Plant Biotechnol J. 2011; 9: 1022-1037.

[17] Raya JG, Melkus G, Adam-Neumair S, Dietrich O, Mützel E, Kahr B, Reiser MF, Jakob PM, Putz R, Glaser C. Change of diffusion tensor imaging parameters in articular cartilage with progressive proteoglycan extraction. Invest Radiol. 2011; 46: 401-409.

[18] Mörchel P, Melkus G, Yaromina A, Zips D, Baumann M, Jakob PM, Flentje M. Correlating quantitative MR measurements of standardized tumor lines with histological parameters and tumor control dose. Radiother. Oncol. 2010; 96: 123-130.

[19] Melkus G, Mörchel P, Behr VC, Kotas M, Flentje M, Jakob PM. Sensitive J-coupled metabolite mapping using Sel-MQC with selective multi spin-echo readout. Mag Reson Med. 2009; 62: 880-887.

[20] Melkus G, Rolletschek H, Radchuk R, Fuchs J, Rutten T, Wobus U, Altmann T, Jakob P, Borisjuk L. The Metabolic Role of Legume Endosperm: Non-invasive Imaging Study. Plant Physiol. 2009; 151: 1139-1154.

[21] Weiss K, Melkus G, Jakob PM, Faber C. Quantitative in vivo 1H Spectroscopic Imaging of metabolites in the early postnatal mouse brain at 17.6 T. MAGMA. 2009; 22: 53-62

[22] Melkus G, Mörchel P, Behr VC, Kotas M, Flentje M, Jakob PM. Short Echo Spectroscopic Imaging combined with Lactate Editing in a Single Scan. NMR Biomed. 2008; 21: 1076-1086.

[23] Ziener CH, Kampf T, Melkus G, Herold V, Weber T, Reents G, Jakob PM, Bauer WR. Local frequency density of states around field inhomogeneities in magnetic resonance imaging: Effects of diffusion. Physical Review E. 2007; 76: 031915

[24] Gareis D, Wichmann T, Lanz T, Melkus G, Horn M, Jakob PM. Mouse MRI using phased-array coils. NMR Biomed. 2007; 20: 326-334

[25] Ziener CH, Kampf T, Melkus G, Jakob PM, Bauer WR. Scaling laws for transverse relaxation times. J Magn Reson. 2007; 184: 169-75

[26] Ziener CH, Bauer WR, Melkus G, Weber T, Herold V, Jakob PM. Structure-specific magnetic field inhomogeneities and its effect on the correlation time. Magn Reson Imaging. 2006; 24: 1341-1347

[27] Balla DZ, Melkus G, Faber C. Spatially localized intermolecular zero-quantum coherence spectroscopy for in vivo applications. Magn Reson Med. 2006; 56: 745-53.

[28] Knorgen M, Spielmann RP, Haberland EJ, Melkus G. Measurement of MRI scanner noise. Z Med Phys. 2004; 14: 251-259