OHRI Chair of Emergency Medicine Research
Senior Scientist, Clinical Epidemiology, Ottawa Hospital Research Institute
Professor and Chair, Department of Emergency Medicine, University of Ottawa
University Health Research Chair, University of Ottawa
Member, School of Graduate Studies and Research, University of Ottawa
Active Staff, Department of Emergency Medicine, Ottawa Hospital
Honours and Awards
Distinguished Professor, University of Ottawa, 2007
Faculty Mentoring Award, Faculty of Medicine, University of Ottawa, 2005
Senior Investigator Award, Society for Academic Emergency Medicine, 2005
Distinguished Investigator, Canadian Institutes of Health Research, 2006
http://www.cihr-irsc.gc.ca/services/databases/distinguished_scientists/2006/index_e.shtml
Member Institute of Medicine, National Academy of Sciences, 2000
http://www.iom.edu/
Order of the International Federation for Emergency Medicine, 2004
Dr. J. David Grimes Research Career Achievement Award, Ottawa Hospital Research Institute, 2002
http://www.ohri.ca/corporate/10292002.asp
Hal Jayne Academic Achievement Award, Society for Academic Emergency Medicine, 2000
http://www.saem.org/
Visiting Professorship in Medical Research, Royal College of Physicians and Surgeons of Canada, 2002
http://rcpsc.medical.org
WG Smith Memorial Lectureship, Sir Charles Gairdner Hospital, Perth Australia, 2001
http://www.scgh.health.wa.gov.au/
Faculty Award of Excellence, Faculty of Medicine, University of Ottawa, 1996
http://www.medicine.uottawa.ca/eng/
Research Interests
Emergency Medicine
Clinical Decision Rules
Cardiac Arrest
Prehospital Resuscitation
Emergency Medicine Research Fellowship
Major Research Activities
Dr. Stiell is a clinical epidemiologist with a focus on health services research
in emergency medicine. This research focus includes decision making, clinical
decision rules, technology assessment and clinical trials involving acutely ill
and injured patients treated by prehospital services and in emergency
departments. Dr. Stiell currently holds a Canadian Institutes of Health Research
Scientist Award. Previously completed were a series of studies to derive,
validate, test and implement clinical decision rules for the use of radiography in
acute ankle injuries (The Ottawa Ankle Rules), and for the use of radiography
in acute knee injury (The Ottawa Knee Rule). Ongoing are studies to derive and validate
clinical decision rules for the use of computed tomography in minor head
injuries and cervical spine radiography in trauma (The CCC Study funded by
the CIHR and the Ministry of Health of Ontario). Dr. Stiell is a member of the
University of Ottawa CIHR Group Grant for Decision Support Tools.
Also currently ongoing is the
Ontario Prehospital Advanced Life Support (OPALS) Study (funded by
the Ontario Ministry of Health) which will identify the most effective
programs for treating out-of-hospital cardiac arrest, major trauma, respiratory
distress, and chest pain. The OPALS Study will be conducted over eight
years in 21 Ontario communities. A grant from the Canadian Health Services
Research Foundation will allow the OPALS Study team to conduct an economic
evaluation of prehospital care.
Another important focus of
research for Dr. Stiell has been the management of cardiac arrest, particularly
in the pre-hospital setting. Completed projects include the study of high
dose epinephrine, a cost-effectiveness study of different pre-hospital
systems used to treat cardiac arrest, a trial of 1,700 patients comparing
the effectiveness of standard CPR versus ACD CPR, and a trial to compare
vasopressin to epinephrine for in-hospital cardiac arrest.
PUBLICATIONS
IN REFEREED JOURNALS (Total = 136)
Most Important Publications
Stiell IG, Clement CM, Rowe BH, Schull MJ, Brison R, Cass D, Eisenhauer MA, McKnight RD, Bandiera G, Holroyd B, Lee JS, Dreyer J, Worthington JR, Reardon M, Greenberg G, Lesiuk H, MacPhail I, Wells GA. Comparison of the Canadian CT Head Rule and the New Orleans Criteria in Patients with Minor Head Injury. JAMA 2005;294:1511-1518. PMID: 16189364
Stiell IG, Wells GA, Field B, Spaite DW, Nesbitt LP, De Maio VJ, Nichol G, Cousineau D, Blackburn J, Munkley D, Luinstra Toohey L, Campeau T, Dagnone E, Lyver M, for the OPALS Study Group. Advanced Cardiac Life Support in Out-of-Hospital Cardiac Arrest. New Engl J Med 2004;351:647-656. PubMedID: 15306666
Stiell IG, Clement CM, McKnight RD, Brison R, Schull MJ, Rowe BH, Worthington JR, Eisenhauer MA, Cass, D, Greenberg G, MacPhail I, Dreyer J, Lee JS, Bandiera G, Reardon M, Holroyd B, Lesiuk H, Wells GA. The Canadian C-Spine Rule versus the NEXUS low-risk criteria in patients with trauma. New Engl J Med 2003;349:2510-2518. PubMedID: 14695411
Stiell IG, Nichol G, Wells GA, De Maio V, Nesbitt L, Blackburn J, Spaite D, for the OPALS Study Group. Health-related quality of life is better for cardiac arrest survivors who received citizen CPR. Circulation 2003;108:1939-1944. PubMedID: 14530198
Stiell IG,
Wells GA, Vandemheen KL, Clement CM, Lesiuk H, De Maio VJ, Laupacis A,
Schull M, McKnight RD, Verbeek R, Brison R, Cass D, Dreyer J, Eisenhauer
MA, Greenberg GH, MacPhail I, Morrison L, Reardon M, Worthington J. The
Canadian Cervical Spine Radiography Rule for alert and stable trauma patients.
JAMA 2001;286:1841-1848. PubMed
ID: 11597285
Stiell IG,
Hebert PC, Wells GA, Vandemheen K, Tang ASL, Higginson LAJ, Dreyer JF,
Clement C, Battram E, Watpool I, Mason S, Klassen T, Weitzman B. Vasopressin
versus epinephrine for in-hospital cardiac arrest: a randomized controlled
trial. The Lancet 2001;358:105-109. PubMed
ID: 11463411
Stiell IG,
Wells GA, Vandemheen K, Clement C, Lesiuk H, Laupacis A, McKnight RD,
Verbeek R, Brison R, Cass D, Eisenhauer MA, Greenberg GH, Worthington
J, for the CCC Study Group. The Canadian CT Head Rule for patients with
minor head injury. The Lancet 2001;357:1391-1396. PubMed
ID: 11356436
Stiell IG,
Wells GA, Field BJ, Spaite DW, De Maio VJ, Ward R, Munkley DP, Lyver MB,
Luinstra LG, Campeau T, Maloney J, Dagnone E, for the OPALS Study Group.
Improved out-of-hospital cardiac arrest survival through the inexpensive
optimization of an existing defibrillation program (OPALS Study Phase
II). JAMA 1999;281:1175-1181. PubMed
ID: 10199426
Stiell IG
and Wells GA. Methodological standards for the development of clinical
decision rules in emergency medicine. Ann Emerg Med 1999;33:437-447.
PubMed
ID: 10092723
Stiell IG,
Wells GA, Hoag RH, Sivilotti MLA, Cacciotti TF, Verbeek PR, Greenway KT,
McDowell I, Cwinn A, Greenberg GH, Nichol G, Michael JA. Implementation
of the Ottawa Knee Rule for the use of radiography in acute knee injuries.
JAMA 1997;278:2075-2079. PubMed
ID: 9403421
Laupacis A, Sekar N, Stiell
IG. Clinical prediction rules: a review and suggested modifications
of methodological standards. JAMA 1997;277-6:488-494. PubMed
ID: 9020274
Stiell IG,
Hébert PC, Wells, GA, Laupacis A, Vandemheen K, Dreyer, JF, Eisenhauer
MA, Gibson J, Higginson LAJ, Kirby AS, Mahon JL, Maloney JP, Weitzman
BN. The Ontario trial of active compression-decompression cardiopulmonary
resuscitation for in hospital and prehospital hospital cardiac arrest.
JAMA 1996;275-18:1417-1423. PubMed
ID: 8618367
Stiell IG,
Greenberg GH, Wells GA, McDowell I, Cwinn AA, Smith NA, Cacciotti TF,
Sivilotti MLA. Prospective validation of a decision rule for the use of
radiography in acute knee injuries. JAMA 1996;275-8:611-615. PubMed
ID: 8594242
Stiell IG,
Wells GA, Laupacis A, Brison R, Verbeek R, Vandemheen K, Naylor CD. A
multicentre trial to introduce clinical decision rules for the use of
radiography in acute ankle injuries. Br Med J 1995;311:594-597.
PubMed
ID: 7663253
Stiell IG,
Greenberg GH, Wells GA, McKnight RD, Cwinn AA, Cacciotti T, McDowell I,
Smith NA. The derivation of a decision rule for the use of radiography
in acute knee injuries. Ann Emerg Med 1995;26:4:405-413. PubMed
ID: 7574120
Stiell IG,
McKnight RD, Greenberg GH, McDowell I, Nair RC, Wells GA, Johns C, Worthington
JR. Implementation of the Ottawa Ankle Rules. JAMA 1994;271:827-832.
PubMed
ID: 8114236
Stiell IG,
Greenberg GH, McKnight RD, Nair RC, McDowell I, Reardon M, Stewart, JP,
Maloney J. Decision rules for the use of radiography in acute ankle injuries:
refinement and prospective validation. JAMA 1993;269:1127-32. PubMed
ID: 8433468
Stiell IG,
Greenberg GH, McKnight RD, Nair RC, McDowell I, Worthington JR. A study
to develop a clinical decision rule for the use of radiography in acute
ankle injuries. Ann Emerg Med 1992;21:384-90. PubMed
ID: 1554175
Stiell IG,
Hébert PC, Weitzman BN, Wells GA, Raman S, Stark RM, Higginson LAJ, Ahuja
J, Dickinson GE. High-dose epinephrine in adult cardiac arrest. New
Engl J Med 1992;327:1045-50. PubMed
ID: 1522840
RESEARCH FUNDING
Peer-Reviewed Principal
Investigator:
Canadian Institutes of Health Research 2005-2009
Resuscitation Outcomes Consortium Epistry Study
National Institutes of Health 2004-2009
Proposal to create a Canadian Collaborative Regional Clinical Center within the Resuscitation Research Consortium
Canadian Health Services Research Foundation 2004-2007
Improved Emergency Department Efficiency Through Triage Nurse Evaluation of Immobilized Trauma Patients
(Co-Principal Investigator – Dr. Annette O’Connor).
National Institutes of Health 2003-2005
Optimal prehospital care for childhood cardiac arrest
Canadian Institutes of Health Research 2003-2007
Evaluation of an active strategy to implement the Canadian CT Head Rule: Phase III
Canadian Institutes of Health Research 2003-2006
Ontario Prehospital Advanced Life Support (OPALS) Study for critically ill and injured pediatric patients (Co-Principal Investigator – Dr. Martin Osmond)
Ontario Ministry of Health and Long-Term Care 2002-2003
The Prehospital Validation of the Canadian C-Spine Rule by Paramedics (Co-Principal Investigator -Dr. Christian Vaillancourt)
Physician Services Foundation Institute 2003-2005
The prehospital validation of the Canadian C-Spine Rule by Paramedics (Co-Principal Investigator - Dr. Christian Vaillancourt)
Canadian Institutes of Health Research 2003-2007
Implementation of the Canadian C-Spine Rule (Phase III)
Ontario Ministry of Health 2000-2003
A study to prospectively validate a Clinical decision rule for the use of
computed tomography in patients with minor head injury (Phase II).
Canadian Institutes of Health Research 2000-2003
A study to prospectively validate a clinical decision rule for the use of
computed tomography in patients with minor head injury.
Canadian Institutes of Health Research 2000-2003
Group grant in decision support tools for patients and clinicians
Canadian Health Services Research Foundation 1998-2001
The Ontario Prehospital Advanced Life Support (OPALS) Study for Cardiac
Arrest and Critical Care Patients - Phase III.
Ontario Ministry of Health 1994-2004
Ontario Prehospital Advanced Life Support Study
Peer-Reviewed Co-Investigator:
Canadian Institutes of Health Research 2006-2010
A study to prospectively validate a clinical decision rule for the investigation of alert patients suspected of having subarachnoid hemorrhage (Phase II)
Principal Investigator – Dr. Jeff Perry
Ontario Lung Association/Children’s Hospital of Eastern Ontario Research Institute 2005-2007
A study to derive a clinical decision rule for predicting severe bronchiolitis
Principal Investigator – Dr. Amy Plint
Canadian Institutes of Health Research 2005-2009
A study to validate a clinical decision rule for the use of computed tomography in children with minor head injury
Principal Investigator – Dr. Martin Osmond
Canadian Institutes of Health Research 2005-2007
Multi-centered study of anti-inflammatory treatment in asthma relapse: The AIR asthma study
Principal Investigator - Dr. Brian Rowe
Canadian Institutes of Health Research 2004-2009
Group grant in decision support tools for patients and clinicians
Canadian Institutes of Health Research 2004-2007
The Ontario Outcomes after the Hospitalization Study (The Ontario OATH Study)
Principal Investigator – Dr. Carl Van Walraven
Canadian Institutes of Health Research 2004-2007
A study to complete the derivation of a clinical decision rule to guide investigation of patients with an acute headache to rule out non-traumatic subarachnoid hemorrhage
Principal Investigator – Dr. Jeff Perry
Canadian Institutes of Health Research 2003-2005
A randomized trial comparing clarithromycin to first-line antibiotics for the out-patient treatment of acute COPD
Principal Investigator - Dr. Brian Rowe
Ontario Ministry of Health and Long-Term Care 2002-2003
Study to determine the accuracy of spectrophotometry for subarachnoid hemorrhage
Principal Investigator - Dr. Jeff Perry.
Canadian Association of Emergency Physicians 2002-2003
A National Survey of Canadian Emergency Physicians: How you manage traumatic corneal abrasions?
Principal Investigator – Dr. Lisa Calder
Canadian Association of Emergency Physicians 2002-2003
Understanding and improving low bystander CPR. A systematic review and meta-analysis of the literature
Principal Investigator – Dr. Christian Vaillancourt
Physician’s Services Incorporated Foundation 2002-2003
Uptake and use of clinical decision rules
Principal Investigator – Dr. Jamie Brehaut
Physician's Services Incorporated Foundation 2001-2003
A Study to Derive a Clinical Decision Rule for the Investigation of Alert
Patients Suspected of having Subarachnoid Haemorrhage - Phase 1
Principal Investigator - Dr. Jeff Perry
Ontario Neurotrauma Foundation 2001-2004
A Prospective Study of Mild Traumatic Brain Injury
Principal Investigator - Dr. Shawn Marshall
Canadian Institutes of Health Research 2001-2003
Pulmonary Embolism Diagnosis Study
Principal Investigator - Dr. David Anderson
Canadian Institutes of Health Research 2001-2005
A study to derive and validate a clinical decision rule for the use of computed
tomography for children with minor head injury.
Principal Investigator - Dr. Martin Osmond
Non-Peer-Reviewed Principal Investigator:
Astellas Pharma Corp 2005-2006
Atrial Fibrillation Study – Phase IV
Cardiome Pharma Corp 2004-2005
Atrial Fibrillation Study – Phase III
Cardiome Pharma Corp 2001-2002
Atrial Fibrillation Study – Phase I and II
Medtronic Physio-Control Inc. 2001-2002
Biphasic Defibrillation Pilot Study
Civic Campus
(see 
