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Contact Information

Douglas Gray, PhD

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Selected Publications

Vlasschaert, C., Cook, D., Xia, X., and Gray, D.A. (2017) The Evolution and Functional Diversification of the Deubiquitinating Enzyme Superfamily.  Genome Biology and Evolution 9(3):558–573
Vlasschaert, C., Xia, X., and Gray, D.A. (2016) Selection preserves Ubiquitin Specific Protease 4 alternative exon skipping in therian mammals.  Scientific Reports 6, 20039.
Vlasschaert, C., Xia, X., Coulombe, J., and Gray, D.A. (2015) Evolution of the highly networked deubiquitinating enzymes USP4, USP15 and USP11. BMC Evolutionary Biology, 15:230
Coulombe, J., Gamage., P., Gray, M., Iqbal., M., Zhang, M., Tang., M.Y., Woulfe, J., Saffrey, J., and Gray, D.A. (2014) Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system. Frontiers in Aging Neuroscience. | doi: 10.3389/fnagi.2014.00129
Gray, D.A., and Woulfe., J. (2013) Structural disorder and the loss of RNA homeostasis in aging and neurodegenerative disease. Frontiers in Genetics. 4:149. doi: 10.3389/fgene.2013.00149
Tang, M.Y., Proctor, C.J., Woulfe, J., and Gray, D.A. (2010) Experimental and Computational Analysis of Polyglutamine-Mediated Cytotoxicity. PLoS Computational Biology 6(9): e1000944.

All Other Publications

Proctor, C.J., and Gray, D.A. (2012) A unifying hypothesis for familial and sporadic Alzheimer's disease. International Journal of Alzheimer's Disease 2012, Article ID 978742.
McBurney, M.W., Clark-Knowles, K.V., Caron, A.Z., and Gray, D.A. (2013) SirT1 is a highly networked protein that mediates adaptation to chronic physiological stress. Genes and Cancer, published on February 7, 2013 as doi:10.1177/1947601912474893.
Proctor, C.J., Boche, D., Gray, D.A., and Nicoll, J.A.R. (2013) Investigating interventions in Alzheimer's disease with computer simulation models. PLoS One 2013 Sep 16;8(9):e73631.
Gray, M.T., Munoz, D.G., Nussbaum, R.L., Gray. D.A., Schlossmacher, M.G., and Woulfe, J.M. (2013) alpha-synuclein in the appendiceal mucosa of neurologically intact subjects. Movement Disorders published online: 18 DEC 2013 DOI: 10.1002/mds.25779
Woulfe, J.M., Gray, M.T., Gray, D.A., and Mittledorp. J. (2014) Hypothesis: A Role for EBV-induced molecular mimicry in Parkinson's Disease. Parkinsonism and Related Disorders. DOI: 10.1016/j.parkreldis.2014.02.031
Read, N.C., Coulombe, J., Carter, A., Zhang, M., Gutsol, A., Gray, D.A., and Kennedy, C. (2014) Gene-targeted ubiquitin C-terminal hydrolase L1 deletion ameliorates glomerular injury in mice with ACTN4-associated focal segmental glomerulosclerosis. Biochemica Biophysica Acta 1842 (7):1028-40.
Radwan, M., Wilkinson, D., Wang, H., Barter, M.J., Gibson, B., Coulombe, J., Gray, D.A., Rowan, A.D., and Young, D.A. (2014) Protection of murine osteoarthritis by inhibition of the 26S proteasome and lysine-48 linked ubiquitination. Annals of the Rheumatic Diseases. 2014 Apr 8. doi: 10.1136/annrheumdis-2013-204962. [Epub ahead of print]
Gray, M.T., Gray. D.A., and Woulfe, J.M. (2014) Reply to: Alimentary, my dear Watson? The challenges of enteric α-synuclein as a Parkinson's disease biomarker. Movement Disorders 2014 Jun 13. doi: 10.1002/mds.25942. [Epub ahead of print]

Listings from The Ottawa Hospital Library

This lists the 10 most recent publications in The Ottawa Hospital's Library database from this lab.This database only starts tracking a researcher's publications once they start working at the Ottawa Hospital Research Institute.
More publications may be available in The Ottawa Hospital Library database.