262 career peer-reviewed research publications. 85 in the past 5 years.


Aaron SD, Vandemheen K, Whitmore GA, et al.  Early Diagnosis and Treatment of COPD and Asthma: A Randomized, Controlled Trial.  The New England Journal of Medicine 2024 Jun 13;390(22):2061-2073.  

Aaron SD, Vandemheen K, FitzGerald JM, et al.  Reevaluation of Diagnosis in Adults with Physician-Diagnosed Asthma.  JAMA 317(3):269-279, 2017.

Aaron SD, Vandemheen KL, Ramotar K, et al. Infection with transmissible strains of Pseudomonas aeruginosa and clinical outcomes in adults with cystic fibrosis. JAMA 304 (19): 2145-2153, 2010.

Aaron SD, Vandemheen KL, Fergusson D, Maltais F, Bourbeau J, Goldstein R, et al. Tiotropium in combination with placebo, salmeterol or fluticasone/salmeterol for treatment of chronic obstructive pulmonary disease: A randomized trial. Annals of Internal Medicine 146 (8):545-555, 2007.

Aaron SD, Vandemheen KL, Ferris W, Fergusson D, Tullis E, Haase D, Berthiaume Y, Brown N, Wilcox P, Yozghatlian V, Bye P, Bell S, Chan F, Rose B, Jeanneret A, Stephenson A, Noseworthy M, Freitag A, Paterson N, Doucette S, Harbour C, Ruel M, MacDonald M. Combination Antibiotic Susceptibility Testing to Treat Exacerbations of Cystic Fibrosis Associated with Multi-Resistant Bacteria: A Randomized, Double-Blind, Controlled Clinical Trial. The Lancet 366: 463-71, 2005.

Aaron SD, Vandemheen K, Hebert P, Dales R, Stiell I, Ahuja J, Dickinson G, Brison R, Rowe B, Dreyer J, Yetisir E, Cass D, Wells G. Outpatient oral prednisone after emergency treatment of chronic obstructive pulmonary disease. The New England Journal of Medicine 348, 2618-25, 2003. 

All Other Publications

  1)    Montes de Oca M, Perez-Padilla R, Celli B, Aaron SD, et al.   The Global Burden of COPD: Epidemiology and Impact of Prevention Strategies.  Lancet Resp Med 2025, in press.  
2)    Collins SE, Jensen D, Kirby M, Phillips DB, Molgat-Seon Y, Marciniuk D, Lovinsky-Desir S, Walker B, Aaron SD, Hernandez P, Tan W, Bourbeau J,  Smith B. Smaller Airways or Bigger Lungs? Dysanapsis Etiotypes and Obstructive Pulmonary Physiology at Rest and During Exercise.  Am J Respir Crit Care Med. 2025 May 19.  Online ahead of print.  
3)    Aaron SD, Huynh C, Whitmore GA.  Use of a Single Case-Finding Questionnaire to Simultaneously Target Multiple Related Diseases Allows Enhanced Disease Detection.  Plos One 2025, Mar 3;20(3):e0296206. doi: 10.1371/journal.pone.0296206.  
4)    Izydorczyk C, Waddell B, Thornton C, Conly J, Aaron SD, et al.  Genomic analysis of the Liverpool epidemic strain of pseudomonas aeruginosa infecting persons with cystic fibrosis reveals likely Canadian origins. J of Cystic Fibrosis 2025, https://doi.org/10.1016/j.jcf.2025.02.009.  
5)    Biswas S, Doiron D, Li P, Aaron SD, et al.  Clinically important deterioration in a mild to moderate COPD population.  ERJ Open Research 2025, 01172-2024, 10.1183/23120541.01172-2024.  
6)    Mikaeeli S, Doiron D, Bourbeau J, Li PZ, Aaron SD, Chapman KR, Hernandez P.  COPD Exacerbations, Air Pollutant Fluctuations, and Individual-Level Factors in the Pandemic Era.  Int J of COPD 2025, Vol. 20: 735—751.  
7)    Kendzerska T, Zhu D, Pugliese M, Manuel D, Sadatsafavi M, Povitz M, Stukel T, To T, Aaron SD, et al.  Healthcare utilization trends in adults with asthma or COPD during the first year of COVID-19 pandemic in comparison to pre-pandemic: A population-based study.  Plos One 2025, Mar 6;20(3):e0316553. doi: 10.1371/journal.pone.0316553.  
8)    The Canadian Lung Outcomes in Users of Vaping Devices (CLOUD) Study: protocol for a prospective, observational cohort study.  Burns P, Eddy RL, Li X, Yang J, Dhillon SS, Couillard S, Stickland MK, Guenette J, Svenningsen S, Tulloch T, Samji H, Meza R, Struik LL, Aaron SD, Ho T, Lam S, Leipsic J, Maclean J, Afshar T, Moraes TJ, Zanette B, Santyr G, Counil FP, Hernandez Cordero AI, Matano S, de Arruda Maluf G, Leung C, Feng C, Bal L, Dhaliwal H, Mumuni A, Lui C, Drew H, Sin DD, Rayment JH, Leung JM.  BMJ Open 2025 Mar 6;15(3):e100568. doi: 10.1136/bmjopen-2025-100568.  
9)    Aaron SD. Early Diagnosis of COPD and Asthma.  Chest 2025, 167(4), 943-944.  10) Kwok C, Thavorn K, Amjadi K, Aaron SD, Kendzerska T.  Mortality after treatment of malignant pleural effusions with indwelling pleural catheters versus chemical pleurodesis: A population-based study.  Respiratory Research 2024 Nov 13;25(1):409. doi: 10.1186/s12931-024-03023-6.  
11) Aaron SD, Vandemheen K, Whitmore GA, et al.  Early Diagnosis and Treatment of COPD and Asthma: A Randomized, Controlled Trial.  The New England Journal of Medicine 2024 Jun 13;390(22):2061-2073.  
12) Mazzola R, Aaron SD, Vandemheen K, et al.  Association between Lung Function and Sleep Disorder Symptoms in a Community-Based Multi-Site Case-Finding Study.  J of Sleep Research 2024;e14356. https://doi.org/10.1111/jsr.14356.  
13) Bierbrier J (undergraduate student), Gerstein E, Whitmore GA, Vandemheen K, Bergeron C, Aaron SD (senior author).  Impact of Dyspnea on Adults with Respiratory Symptoms without a Defined Diagnosis.  Chest 2024; 166(6):1296-1308.  
14)   King PJ, Ramic L, Wilson J, Aaron SD, Stiell IG.  Evaluation of the Quality of ED Management for Patients with COPD.  Clin Exp Emerg Med. 2024; 11(3): 269-275.   15) Mai V, Girardi L, de Wit K, Castellucci L, Aaron S, Couturaud F, Fergusson DA, Le Gal G.  Chronic obstructive pulmonary disease exacerbation purulence status and its association with pulmonary embolism: protocol for a systematic review with meta-analysis.  BMJ Open 2024 Jun 19;14(6):e085328. doi: 10.1136/bmjopen-2024-085328.  
16) Aaron SD, Montes de Oca M, Celli B, et al.  Early Diagnosis and Treatment of COPD: The Costs and Benefits of Case-Finding.  Am J Resp Crit Care Medicine 2024 Apr 15;209(8):928-937. doi: 10.1164/rccm.202311-2120PP.  
17) Kwok C, Kendzerska T, Thavorn K, Aaron SD, Amjadi K.  Resource use and costs of indwelling pleural catheters vs pleurodesis for malignant pleural effusions: A population-based study.  Annals American Thoracic Society 2024 Jun;21(6):940-948.  18) Gerstein E (undergraduate student), Bierbrier J (undergraduate student), Whitmore GA, Vandemheen K, Bergeron C, Aaron SD (senior author).  Impact of undiagnosed COPD and asthma on symptoms, quality of life, healthcare utilization and work productivity.  Am J Resp Crit Care Medicine 2023 Dec 15;208(12):1271-1282.   
20) Shin S (medical resident), Whitmore GA, Boulet LP, Boulay ME, Cote A, Bergeron C, Lougheed D, Vandemheen K, Alvarez G, Mulpuru S, Aaron SD (senior author).  Anticipating undiagnosed asthma in symptomatic adults with normal pre- and post- bronchodilator spirometry: A decision tool for bronchial challenge testing.  BMC Pulm Med 2023, 2023 Dec 9;23(1):496. doi: 10.1186/s12890-023-02806-9.  
21) Kendzerska T, Zhu D, Pugliese M, Manuel D, Sadatsafavi M, Povitz M, Stukel T, To T, Aaron SD, et al.  Trends in Outpatient and Inpatient Visits for Separate Ambulatory-Care-Sensitive Conditions during the First Year of the COVID-19 Pandemic: A Province-Based Study. Frontiers in Public Health 2023,11:1251020. doi: 10.3389/fpubh.2023.1251020.  
22) Magner KM (respirology resident), Cherian M (clinical fellow), Whitmore GA, Vandemheen K, Aaron SD (senior author).  Assessment of Preserved Ratio Impaired Spirometry (PRISm) Using Pre and Post Bronchodilator Spirometry in a Randomly-Sampled Symptomatic Cohort. Am J Resp Crit Care Medicine 2023; 208(10): 1129-1131.  
23) Bourbeau J, Bhutani M, Hernandez P, Aaron SD, Beauchesne MF, Kermelly SB, D'Urzo A, Lal A, Maltais F, Marciniuk JD, Mulpuru S, Penz E, Sin DD, Van Dam A, Wald J, Walker BL, Marciniuk DD.  2023 Canadian Thoracic Society Guideline on Pharmacotherapy in Patients With Stable COPD.  Chest 2023 Nov;164(5):1159-1183. 24) Celli B, Fabbri LM, Aaron SD, Agusti A,et al.  Differential Diagnosis of Suspected COPD Exacerbations in the Acute Care Setting: Best Practice.  Am J Resp Crit Care Medicine 207:1134–44, 2023.   24) Pratt A, Purssell A, Zhang T, Luks V, Bauza X, Mulpuru S, Kirby M, Aaron SD, Cowan J.  Complexity in clinical diagnoses of acute exacerbation of chronic obstructive pulmonary disease.  BMC Pulmonary Medicine 2023 Aug 14;23(1):298. doi: 10.1186/s12890-023-02587-1.  
25) Kendzerska T, Malhotra A, Gershon A, Povitz M, McIsaac D, Aaron SD, Bryson G, Talarico R, Godbout M, Tanuseputro P, Chung F. Association between Opioid Prescription Profiles and Adverse Health Outcomes in Opioid Users Referred for Sleep Disorder Assessment: A Secondary Analysis of Health Administrative Data.   Frontiers in Sleep, Volume 2 – 2023, | https://doi.org/10.3389/frsle.2023.1161857.   26) Ross, B, Bourbeau J, Doiron, D, Li P, Benedetti A, Aaron SD, et al. Short-term air pollution exposure and exacerbation events in mild to moderate COPD: A case-crossover study within the CanCOLD cohort.  Thorax 2023 78(10):974-982.  
27) Krishnan S, Tan W, Farias R, Aaron SD, et al.  Impaired spirometry and chronic obstructive pulmonary disease increase the risk of cardiovascular disease: a Canadian cohort study.  Chest 2023 Sep;164(3):637-649.  
28) Boulet LP, Boulay ME, Cote A, FitzGerald JM, Bergeron C, Lemiere C, Lougheed MD, Vandemheen K, Aaron SD (senior author).  Airway inflammation and hyperresponsiveness in subjects with respiratory symptoms and normal spirometry.  European Resp J 2023 Mar 23;61(3):2201194.  
29) Cherian M (clinical fellow), Magner KM (medical resident), Whitmore GA, Vandemheen K, Aaron SD (senior author).  Patient and physician factors associated with symptomatic undiagnosed asthma or COPD.  European Resp J 2023 Feb 23;61(2):2201721.  
30) Katsuno N,  Li P,  Bourbeau J, Aaron SD, Maltais F, et al.  Factors Associated with Attrition in a Longitudinal Cohort of Older Adults in the Community.  Chronic Obstr Pulm Dis 2023; 10(2): 178-189.  

For more publications use this PubMed ID link.